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Author: James C. Taylor
Publisher: Nova Science Publishers
ISBN: 9781617287732
Category : Chemistry
Languages : en
Pages : 0
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Book Description
This book presents original research results on the leading edge of chemistry research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. Some of the topics included in this compilation are the physico-chemical properties and biological activities of copper; the possible applications of layered-perovskite-like oxides; mechanisms of covalent bond heterolysis and the runaway reaction of methyl ethyl ketone peroxide.
Author: James C. Taylor
Publisher: Nova Science Publishers
ISBN: 9781617287732
Category : Chemistry
Languages : en
Pages : 0
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Book Description
This book presents original research results on the leading edge of chemistry research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum. Some of the topics included in this compilation are the physico-chemical properties and biological activities of copper; the possible applications of layered-perovskite-like oxides; mechanisms of covalent bond heterolysis and the runaway reaction of methyl ethyl ketone peroxide.
Author: James C. Taylor
Publisher:
ISBN: 9781536150636
Category :
Languages : en
Pages : 0
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Book Description
In this compilation, the authors begin by highlighting the recent developments in asymmetric 1,4- and 1,2- additions to α, β-unsaturated carbonyl compounds. The recent finding of Cu (I)-catalyzed asymmetric 1,2-addition of Grignard reagents to α, β-unsaturated carbonyl compounds, as well as aromatic ketones, has categorically revolutionized catalytic asymmetric reactions.This compilation also aims to use the well-known coordination preference of zinc in phthalocyanine and porphyrin ligands in correlation with supramolecular systems. The light-absorption process in dye-sensitized solar cells is studied using the time-dependent density functional theory.In recent years, a series of investigations on detonation wave formation in acetylene have been published. In these studies, it was shown that the formation of detonation proceeds entirely due to the energy released during the condensation of carbon nanoparticles during the growth of poly-aromatic hydrocarbons. The results of these studies are summarized and practical applications are discussed.The authors discuss aromatic amines, derivatives of aromatic hydrocarbons containing an amino group/an amine group/nitrogen atom in their structures. These compounds represent one of the most important classes of industrial and environmental chemicals. Three groups have been studied: monocyclic, polycyclic, and heterocyclic aromatic amines, which are used as intermediates in azo dye manufacturing, pigments, drugs, antibiotics, antidepressants, pesticides, and other industrial products.In the closing study, the GC-MS/MS method has been developed for the determination and quantification of 35 multiclass pesticide residues in chili samples. Pesticides were selected from different families including organochlorines, organophosphorus, carbamates, pyrethroids, triazines, triazoles, and pyrazoles. The QuEChERS-dSPE method was used for the extraction of pesticide residue.
Author: B.E. Maryanoff
Publisher: Elsevier
ISBN: 0080526373
Category : Science
Languages : en
Pages : 338
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Book Description
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
Author: James C. Taylor
Publisher:
ISBN: 9781536179217
Category :
Languages : en
Pages : 284
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Book Description
Advances in Chemistry Research. Volume 62 first provides information related to the synthesis, morphology, crystal structure, and porosity of bentonite and bentonite/magnetite powders. Following this, the authors discuss carbon tetrachloride, a clear, colourless, volatile and very stable chlorinated hydrocarbon with a non-polar nature, making it an excellent solvent.Recent research on the applications of hydrogen peroxide as oxidizing and reducing agent is presented, as well as its application in biocatalysis, as signaling molecule, and in nanochemistry.The mode of action hydrogen peroxide induces in yeast apoptosis is also addressed, including overexpression of apoptosis inducing factor homologue proteins.Additionally, this compilation describes the recent advances concerning the use of hydrogen peroxide in heteropolyacid-catalyzed oxidation reactions of terpenic alcohols, which are renewable origin compounds whose oxidation provides aldehydes and epoxides.Diamines, organic compounds with two amino groups, are described. In one study, different diamines are synthesized with complex formulas used in the preparation of different thermally stable polymers.A few diamines used in developing thin-film polyamide composite membranes are reviewed.The concluding study is focused on gas hydrates, mixtures of light gases such as methane, ethane or carbon dioxide, and water molecules under a special temperature and pressure condition, forming a liquid-like material.
Author: James C. Taylor
Publisher:
ISBN: 9781685071837
Category :
Languages : en
Pages : 0
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Book Description
This edited volume comprises five chapters, each detailing recent updates in chemistry research. Chapter One describes different types of polymer electrolytes and their preparation methods as well as ion transport mechanisms, methods of improving properties, and techniques for evaluating their structure and properties. Chapter Two analyzes the scopes and limitations of chromatography, NMR spectroscopy, and UV spectroscopy for assigning fullerene C60 regioisomeric multiadducts. Chapter Three focuses on electrochemical techniques used for developing insulin sensors of high specificity and sensitivity. Chapter Four presents selected contemporary achievements of different computational methods in modeling of natural and newly synthesized compounds with determined antibacterial, antifungal and antiviral activities. Lastly, Chapter Five reviews some metal porphyrins of manganese, cobalt, vanadium, and chromium and their catalytic applications.
Author: Kumi Yoshida
Publisher: John Wiley & Sons
ISBN: 1118883268
Category : Science
Languages : en
Pages : 396
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Book Description
Plant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins), are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents. Sponsored by the scholarly society Groupe Polyphénols, this publication, which is the fifth volume in this highly regarded Recent Advances in Polyphenol Research series, is edited by Kumi Yoshida, Véronique Cheynier and Stéphane Quideau. They have once again, like their predecessors, put together an impressive collection of cutting-edge chapters written by expert scientists, internationally respected in their respective field of polyphenol sciences. This Volume 5 highlights some of the latest information and opinion on the following major research topics about polyphenols: • Chemistry, physicochemistry & materials science • Biosynthesis, genetic & metabolic engineering • Plant & ecosystem, lignocellulosic biomass • Food, nutrition & health • Natural medicine & Kampo • Tannins & their functions Chemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists will all find this book an invaluable resource. Libraries in all universities and research institutions where these disciplines are studied and taught should have copies on their bookshelves.
Author: Atta-ur- Rahman
Publisher: Elsevier
ISBN: 0444595155
Category : Science
Languages : en
Pages : 421
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Book Description
Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry. Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry
Author: Douglas Henderson
Publisher: Academic Press
ISBN: 9780126819069
Category : Chemistry, Physical and theoretical
Languages : en
Pages : 328
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Book Description
Author: Edeildo Ferreira Da Silva, Jr.
Publisher:
ISBN: 9781536163681
Category :
Languages : en
Pages : 366
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Book Description
Advances in Medicinal Chemistry Research is a book addressed to undergraduate and postgraduate students, where recent advances in the discovery and development of effective agents against the most remarkable wide-reaching diseases are presented, divided into seven chapters. This first edition of Advances in Medicinal Chemistry Research offers insights into medicinal chemistry that arguably have the most significant impact on our lives than any other. It draws together research on therapeutic agents from natural, synthetic, and virtual screening sources as starting points for the design of drugs against obesity, multidrug-resistant bacteria, neglected tropical diseases, Alzheimer, and cancer. From the prediction of promising hits and identification of active compounds to the extraction of more complex molecules, this book explores a range of essential topics to support the development of novel, economical, and efficacious therapeutics for these diseases, which currently affect a billion people worldwide. Beginning with an overview of obesity, showing the current research landscape, the books shows the importance of natural and synthetic products as promising anti-obesity agents. Subsequently, the medicinal chemistry of modulation of bacterial resistance is presented, focusing on the MFS, RND, ABC, and MATE superfamilies. The book goes on to discuss such topics as antituberculosis, antileishmanial, and anti-hepatitis thiophene-containing compounds, under the medicinal chemistry point of view. Also, potent human glutaminyl cyclase inhibitors are deeply discussed and displayed as hopeful anti-Alzheimer's agents. The last three chapters are focused on the development of researches involving new anticancer agents, initializing with LBDD, SBDD, QSAR, and QM/MM methods applied to the identification of novel promising anticancer compounds. Moreover, IDO1 inhibitors are exhaustively explored and analyzed as a new promise for the immunotherapy of cancer. Finally, a great update on Eg5 kinesin inhibitors is provided, exploring different chemical classes of synthetic and natural compounds, including miscellanea as a new approach for Eg5 inhibition. Combining the expertise of researchers from around the world, this volume aims to support and encourage researches for the development of novel, safe, and active agents against lipase enzyme, bacteria, neglected tropical diseases, Alzheimer, and cancer. The clear narrative truly engages the reader, holding their attention right from the opening of a chapter, and maintaining interest and understanding as a chapter leads into more complex material. Advances in Medicinal Chemistry Research is a book that reviews ongoing developments and recent cutting-edge advances in medicinal chemistry of the most relevant diseases found nowadays, underlining how medicinal chemistry research continues to make significant contributions to the discovery and development of new therapeutic entities. Key Features â¢Chapters written by active specialists and leading experts deeply engaged in the research field of most deadly and limiting diseases for drug discovery. â¢Draws together cutting-edge research advances in medicinal chemistry focused at the obesity, multidrug-resistant microorganisms, Alzheimer, and cancer in a single volume. â¢Highlights the future potential of researches for the medicinal chemistry of most impactful diseases today. â¢Contents addressed to medicinal chemistry, biochemistry, biology, and pharmacy students, professors, and researchers.
Author: BUSH
Publisher: Elsevier
ISBN: 0080551572
Category : Science
Languages : en
Pages : 289
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Book Description
Advances in Biophysical Chemistry, Volume 5, provides reviews of important topics in physical and structural biochemistry. The volume begins with a review of the chemical reactivity of DNA and its relationship to the dynamic nature of DNA conformation and its dependence on base sequence. The underlying chemistry has become extremely important to many researchers who use a host of chemical "footprinting" techniques to study biologically relevant complexes of DNA. This is followed by separate chapters that cover an innovative application of fluorescence energy transfer to investigate the dynamics of complex glycopeptides; the NMR of cations which bind to DNA, providing a picture of DNA conformation and dynamics which is complementary to that provided by 1H NMR spectroscopy; the use of NMR to study electron transfer reactions between cytochrome c peroxidase and cytochrome c; methods for analysis of data on O2 binding by hemoglobin; and experimental methods for obtaining data on protein association.
