Acute Molecular Effects of Resistance Exercise with Superimposed Whole Body Vibration and Vascular Occulsion on Human Skeletal Muscle Gene Expression and Protein Phosphorylation

Acute Molecular Effects of Resistance Exercise with Superimposed Whole Body Vibration and Vascular Occulsion on Human Skeletal Muscle Gene Expression and Protein Phosphorylation PDF Author: Sandra Thöny
Publisher:
ISBN:
Category :
Languages : en
Pages : 44

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Effects of Acute Exercise and Training on Gene Expression and Regulatory Proteins in Human Skeletal Muscle

Effects of Acute Exercise and Training on Gene Expression and Regulatory Proteins in Human Skeletal Muscle PDF Author:
Publisher:
ISBN: 9789178314812
Category :
Languages : en
Pages :

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The Effects of Acute Aerobic and Resistance Exercise on MTOR Signaling and Autophagy in Human Skeletal Muscle

The Effects of Acute Aerobic and Resistance Exercise on MTOR Signaling and Autophagy in Human Skeletal Muscle PDF Author: Corey Mazo
Publisher:
ISBN:
Category : Exercise
Languages : en
Pages : 75

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Book Description
Exercise serves as a powerful stimulus to induce skeletal muscle adaptation. For instance, it is well understood that aerobic exercise (AE) elicits an adaptive response ultimately leading to increased fatigue resistance and capillarization, whereas resistance exercise (RE) is known to elicit an adaptive response leading to increased muscle strength and size. However, the precise molecular mechanisms mediating these unique adaptations to different forms of exercise remain to be completely resolved. The purpose of this study was to investigate the adaptive cellular response of skeletal muscle following acute AE and RE. Specifically, this study focused on two molecular processes: 1) mammalian/mechanistic target of rapamycin (mTOR) signaling pathway, a regulator of muscle protein synthesis, and 2) autophagy, a process through which proteins and organelles are broken down in the muscle fiber. In a counterbalanced, crossover design, six healthy, recreationally active young men (27±3 yr) completed acute AE (40 min of cycling ~70% maximal HR) and acute RE [8 sets, 10 reps, ~65% 1-repetition maximum (1RM)] separated by ~1wk. Muscle biopsies (vastus lateralis) were obtained before, at 1 and 4h post exercise and western blot analyses were used to examine the phosphorylation of mTOR signaling proteins and various markers of autophagy. Phosphorylation of mTORSer2448 increased only following RE at 4h (P

Maj. J. Andre. Miscellaneous

Maj. J. Andre. Miscellaneous PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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The Endocrine System in Sports and Exercise

The Endocrine System in Sports and Exercise PDF Author: William J. Kraemer
Publisher: John Wiley & Sons
ISBN: 0470757809
Category : Medical
Languages : en
Pages : 648

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Book Description
This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.

Craniofacial Muscles

Craniofacial Muscles PDF Author: Linda K. McLoon
Publisher: Springer Science & Business Media
ISBN: 1461444659
Category : Medical
Languages : en
Pages : 339

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Book Description
Of the approximately 640 muscles in the human body, over 10% of them are found in the craniofacial region. The craniofacial muscles are involved in a number of crucial non-locomotor activities, and are critical to the most basic functions of life, including vision, taste, chewing and food manipulation, swallowing, respiration, speech, as well as regulating facial expression and controlling facial aperture patency. Despite their importance, the biology of these small skeletal muscles is relatively unexplored. Only recently have we begun to understand their unique embryonic development and the genes that control it and characteristic features that separate them from the skeletal muscle stereotype. This book is the most comprehensive reference to date on craniofacial muscle development, structure, function, and disease. It details the state-of-the-art basic science of the craniofacial muscles, and describes their unique response to major neuromuscular conditions. Most importantly, the text highlights how the craniofacial muscles are different from most skeletal muscles, and why they have been viewed as a distinct allotype. In addition, the text points to major gaps in our knowledge about these very important skeletal muscles and identified key gaps in our knowledge and areas primed for further study and discovery.

Neuromuscular Performance during Lifespan: Assessment Methods and Exercise Interventions

Neuromuscular Performance during Lifespan: Assessment Methods and Exercise Interventions PDF Author: Oliver Faude
Publisher: Frontiers Media SA
ISBN: 2889632776
Category :
Languages : en
Pages : 196

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Manual of Vibration Exercise and Vibration Therapy

Manual of Vibration Exercise and Vibration Therapy PDF Author: Jörn Rittweger
Publisher: Springer Nature
ISBN: 3030439852
Category : Medical
Languages : en
Pages : 389

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Book Description
This book addresses the practical aspects of vibration exercise and vibration therapy. In addition, it describes the technical and physiological background, providing applied scientists and doctors with a deeper understanding of the therapeutic potential that vibration exercise holds. Having first emerged two decades ago, vibration exercise has since established itself as a widespread form of physical exercise, used in all rehabilitation areas. The goal of this book is to close the gap between scientific knowledge and practice. Given that occupational exposure to vibration leads to well-known unfavorable effects, the book is also dedicated to potential risks, hazards and contra-indications and of course, the application of vibration therapy in a number of specific conditions is presented in a clinically usable fashion. Given its breadth of coverage, this book will be of interest to physiotherapists and exercise scientists, but also to a wider range of physicians working in the field of rehabilitation.

Mechanosensitivity and Mechanotransduction

Mechanosensitivity and Mechanotransduction PDF Author: Irina Kiseleva
Publisher: Springer Science & Business Media
ISBN: 904819881X
Category : Science
Languages : en
Pages : 384

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Book Description
This book presents the latest findings in the field of research of mechanosensitivity and mechanotransduction in different cells and tissues. Mechanosensitivity and mechanotransduction of the heart and vascular cells, in the lung, in bone and joint tissues, in sensor systems and in blood cells are described in detail. This Volume focuses on molecular mechanisms of mechanosensitivity and mechanotransduction via cytoskeleton. Integrin-mediated mechanotransduction, the role of actin cytoskeleton and the role of other cytoskeletal elements are discussed. It contains a detailed description of several stretch-induced signaling cascades with multiple levels of crosstalk between different pathways. It contains a description of the role of nitric oxide in regulation of cardiac activity and in regulation of mechanically gated channels in the heart. In the heart mechanical signals are propagated into the intracellular space primarily via integrin-linked complexes, and are subsequently transmitted from cell to cell via paracrine signaling. Biochemical signals derived from mechanical stimuli activate both acute phosphorylation of signaling cascades, such as in the PI3K, FAK, and ILK pathways, and long-term morphological modii cations via intracellular cytoskeletal reorganization and extracellular matrix remodelling. Cellular and molecular effects of mechanical stretch on vascular cells are also discussed. This Volume highlights the role of mechanotransduction in the lung, in bone and joint tissues. For the first time mechanosensitivity and mechanotransduction in blood cells are discussed. It contains new insights into mechanosensitive K+ channels functioning in mouse B lymphocytes. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. Currently, investigations of the molecular mechanisms of mechanosensitivity and mechanotransduction are focused on several issues. The majority of studies investigate intracellular signaling pathways. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different organs and tissues and allows to predict changes, which arise due to alterations of their environment. Possibly such knowledge will allow the development of new methods of artificial intervention and therapies. This book brings up the problem closer to the experts in related medical and biological sciences as well as practicing doctors besides just presenting the latest achievements in the field.

Progressive Brain Disorders in Childhood

Progressive Brain Disorders in Childhood PDF Author: Juan M. Pascual
Publisher: Cambridge University Press
ISBN: 1107042054
Category : Medical
Languages : en
Pages : 507

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Book Description
A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.