Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030915233X
Category : Nature
Languages : en
Pages : 465

Get Book Here

Book Description
This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030915233X
Category : Nature
Languages : en
Pages : 465

Get Book Here

Book Description
This book is the eighth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and reviews AEGLs for acrolein, carbon monoxide, 1,2-dichloroethene, ethylenimine, fluorine, hydrazine, peracetic acid, propylenimine, and sulfur dioxide for scientific accuracy, completeness, and consistency with the NRC guideline reports.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030917774X
Category : Science
Languages : en
Pages : 320

Get Book Here

Book Description
This book is the sixth volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals, and includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others. At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309182700
Category : Political Science
Languages : en
Pages : 292

Get Book Here

Book Description
This book reviews toxicity documents on five chemicals that can be released in the air from accidents at chemical plants, storage sites, or during transportation. The documents were prepared by the National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances and were evaluated for their scientific validity, comprehensives, internal consistency, and conformance to the 1993 guidelines report.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309283086
Category : Nature
Languages : en
Pages : 291

Get Book Here

Book Description
Extremely hazardous substances (EHSs) can be released accidentally as a result of result of chemical spills, industrial explosions, fires, or accidents involving railroad cars and trucks transporting EHSs. Workers and residents in communities surrounding industrial facilities where EHSs are manufactured, used, or stored and in communities along the nation's railways and highways are potentially at risk of being exposed to airborne EHSs during accidental releases or intentional releases by terrorists. Pursuant to the Superfund Amendments and Reauthorization Act of 1986, the U.S. Environmental Protection Agency (EPA) has identified approximately 400 EHSs on the basis of acute lethality data in rodents. As part of its efforts to develop acute exposure guideline levels for EHSs, EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) in 1991 requested that the National Research Council (NRC) develop guidelines for establishing such levels. In response to that request, the NRC published Guidelines for Developing Community Emergency Exposure Levels for Hazardous Substances in 1993. Subsequently, Standard Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Substances was published in 2001, providing updated procedures, methodologies, and other guidelines used by the National Advisory Committee (NAC) on Acute Exposure Guideline Levels for Hazardous Substances and the Committee on Acute Exposure Guideline Levels (AEGLs) in developing the AEGL values. Using the 1993 and 2001 NRC guidelines reports, the NAC-consisting of members from EPA, the Department of Defense (DOD), the Department of Energy (DOE), the Department of Transportation (DOT), other federal and state governments, the chemical industry, academia, and other organizations from the private sector-has developed AEGLs for more than 270 EHSs. In 1998, EPA and DOD requested that the NRC independently review the AEGLs developed by NAC. In response to that request, the NRC organized within its Committee on Toxicology (COT) the Committee on Acute Exposure Guideline Levels, which prepared this report. This report is the fourteenth volume in that series. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 14 summarizes the committee's conclusions and recommendations.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309290252
Category : Science
Languages : en
Pages : 293

Get Book Here

Book Description
At the request of the Department of Defense and the Environmental Protection Agency, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for several chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies, such as accidental or intentional chemical releases in community, workplace, transportation, and military settings, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 13 includes AEGLs for boron trifluoride, bromoacetone, chloroacetone, hexafluoroacetone, perchloryl fluoride, piperidine, propargyl alcohol, trimethoxysilane and tetramethoxysilane, and trimethylbenzenes.

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309170869
Category : Political Science
Languages : en
Pages : 224

Get Book Here

Book Description
Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routesâ€"both oral and dermalâ€"as well as risk assessors in the government, academe, and private industry.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309178908
Category : Science
Languages : en
Pages : 292

Get Book Here

Book Description
In 1993, the National Research Council's Committee on Toxicology developed criteria and methods for EPA and the Agency for Toxic Substances and Disease Registry (ATSDR) to develop community emergency exposure levels for extremely hazardous substances for the general population. A few years later, the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC)â€"composed of members of EPA, DOD, other federal and state agencies, industry, academia, and other organizationsâ€"was established to identify, review, and interpret toxicologic and other scientific data to develop acute exposure guidelines (AEGLs) for high-priority, acutely toxic chemicals. Three levelsâ€"AEGL-1, AEGL-2, and AEGL-3 are developed for each of five exposure periods (10 min, 30 min, 1 hr, 4 hr, and 8 hr) and are distinguished by varying degrees of severity of toxic effects. This current report reviews the NAC reports for their scientific validity, completeness, and consistency with the NRC guideline reports developed in 1993 and 2001. This report is the fifth volume in the series and covers AEGLs for chlorine dioxide, chlorine trifluoride, cyclohexylamine, ethylenediamine, hydrofluoroether-7100, and tetranitromethane. It concludes that the AEGLs developed by NAC are scientifically valid and consistent with the NRC guideline reports. AEGLs are needed for a wide range of planning, response, and prevention applications. These values provide data critical to evacuation decisions and discussions between community leaders and industries as they seek ways to minimize the health impact should the chemical release occur. Some of the finalized AEGLs have been officially adopted by the Department of the Army, FEMA, and the Department of Transportation as the official levels for use by those agencies.

Acute Exposure Guideline Levels for Selected Airborne Chemicals

Acute Exposure Guideline Levels for Selected Airborne Chemicals PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309254817
Category : Nature
Languages : en
Pages : 356

Get Book Here

Book Description
At the request of the Department of Defense and the Environmental Protection Agency, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for several chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies, such as accidental or intentional chemical releases in community, workplace, transportation, and military settings, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. This volume in the series includes AEGLs for bis-chloromethyl ether, chloromethyl methyl ether, chlorosilanes, nitrogen oxides, and vinyl chloride.

Toxicological Profile for Hexachlorobutadiene

Toxicological Profile for Hexachlorobutadiene PDF Author:
Publisher:
ISBN:
Category : Butadiene
Languages : en
Pages : 168

Get Book Here

Book Description


Toxicological Profile for Isophorone

Toxicological Profile for Isophorone PDF Author:
Publisher:
ISBN:
Category : Halocarbons
Languages : en
Pages : 120

Get Book Here

Book Description