Author: Dieter K. Lüdecke
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 344

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Book Description

Author: Edward R. Laws Jr
Publisher: Academic Press
ISBN: 0128043903
Category : Medical
Languages : en
Pages : 240

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Book Description
Cushing's Disease: An Often Misdiagnosed and Not So Rare Disorder reviews the epidemiology of Cushing's, including statistics on the incidence and prevalence of this disease. There are discussions of the signs and symptoms and the most common co-morbidities, such as diabetes mellitus, hypertension, osteoporosis, amenorrhea, and infertility. Surgical, medical, and radiotherapeutic treatments, including indications, results, risks, and complications, are reviewed. Also featured is a chapter on the patient's perspective, coping with Cushing's, quality of life, and psychosomatic issues. This book is essential reading for the wide range of physicians who treat patients with Cushing's disease symptoms, as well as biomedical researchers who investigate the etiology and mechanisms of rare genetic diseases, in particular rare endocrine disorders. - Reviews the basics of Cushing's disease and its interrelation with hormones, the brain, and bodily functions - Includes chapters on diagnosis, surgical, medical, and radiotherapeutic treatments, and variations in presentation, including cyclical disease - Presents the cognitive and emotional aspects of Cushing's and the long-term sequelae - Offers an important resource for physicians who are accustomed to treating individual symptoms rather than a disease complex - Reviews multidisciplinary management, and post-treatment management of Cushing's, including recommendations for Cushing's Centers of Excellence

Author: Marcello D. Bronstein
Publisher: Springer Science & Business Media
ISBN: 1603274499
Category : Medical
Languages : en
Pages : 304

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Book Description
Cushing ́s syndrome is a relatively rare clinical disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function and growth impairment in children, all of which severely reduce quality of life and life expectancy. Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment reviews the difficulties in distinguishing Cushing’s syndrome from these and other common conditions, such as central obesity, menstrual irregularity and depression. It also provides state-of-the-art information on various strategies to establish the diagnosis of Cushing’s syndrome and the differential diagnosis among its diverse etiologies, as well as therapeutic approaches. Additionally, a range of conditions that represent challenges for the diagnosis and treatment--such as renal failure, pediatric age, cyclic hypercortisolism, and pregnancy--are covered in detail. A valuable resource not only for endocrinologists but also internal medicine physicians, gynecologists, pediatricians, , pituitary surgeons and urologists, Cushing’s Syndrome: Pathophysiology, Diagnosis and Treatment provides insights by experts that will help all physicians dealing with Cushing ́s syndrome to expand their knowledge about the condition and provide targeted, comprehensive care.

Author: Leo Plouffe, Jr
Publisher: Cambridge University Press
ISBN: 1316298876
Category : Medical
Languages : en
Pages : 261

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Book Description
A practical approach to the field of androgen excess or deprivation in women's health. The content includes multiple viewpoints on the most common disorders in this class, such as polycystic ovary disease, hirsutism and menopausal issues. Each chapter provides a combination of long-lasting clinical principles in the diagnosis and management of these patients along with a state-of-the-art review. This text takes an innovative approach to uncommon conditions (such as congenital adrenal hyperplasia, transgender conditions). In addition to presenting clinical insights, and a review of the basic science underpinning these conditions, it focuses on key concepts that can be derived from these rare conditions to the entire field. This book is an essential addition to the library for any busy clinician who is looking for a practical reference guide but also for the sub-specialist who is looking for new and thought-provoking insights in this complex scientific area.

Author: Andrew N. Margioris
Publisher: Springer Science & Business Media
ISBN: 1592591019
Category : Medical
Languages : en
Pages : 420

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Book Description
In Adrenal Disorders, a panel of distinguished physicians and researchers select the most relevant new findings and integrate them into the existing body of clinical knowledge on adrenal pathologies. The book includes important reviews of disturbances in cortisol homeostasis, and new concepts regarding adrenal tumors and hereditary adrenal diseases. Also discussed are mineralocorticoids and the syndromes of mineralocortoid excess and aldosterone synthase deficiency. Authoritative and insightful, Adrenal Disorders provides physicians and scientists with a comprehensive, state-of-the-art practical guide to the devastating diseases of the adrenals that are so often difficult to diagnose and treat.

Author: Brooke Swearingen
Publisher: Springer Science & Business Media
ISBN: 1461400112
Category : Medical
Languages : en
Pages : 267

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Book Description
In Cushing’s Disease, leading authorities in the field offer a thorough review of the pathogenesis, diagnostic algorithm and treatment options for this complex disease. Beginning with a fascinating history of Cushing's disease that outlines its historical significance to both endocrinology and neurosurgery, the book goes onto to cover the full range of important issues, including the molecular pathogenesis of Cushing’s, anatomic pathology, the diagnosis of Cushing's syndrome, the differential of pseudo-Cushing's syndromes, hypercortisolemia, surgical removal of the corticotroph adenoma, post-operative management and assessment of remission, radiotherapeutic options, and the exciting developments in medical therapy. In addition, the book also addresses Cushing's disease in the pediatric population, given that its clinical manifestations and impact on growth can be severe; silent corticotroph adenomas as a distinct clinical entity; diagnosis and management of Cushing's disease during pregnancy, bilateral adrenalectomy, and, finally, the long-term psychological manifestations of hypercortisolemia. Comprehensive and an invaluable addition the literature, Cushing’s Disease is an essential reference for enhancing diagnosis and treatment of this debilitating disorder.

Author: Andrea Dunaif
Publisher: Springer Science & Business Media
ISBN: 1597451088
Category : Medical
Languages : en
Pages : 361

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Book Description
This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Author: Salvatore Docimo Jr.
Publisher: Springer
ISBN: 3319984977
Category : Medical
Languages : en
Pages : 786

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Book Description
As the field of general surgery continues to expand, the diagnostic and therapeutic pathways are becoming more complex. The diagnostic modalities available to the clinician can be both very helpful but also overwhelming considering the findings can often determine the scope of treatment for a patient. This text will take the major pathologies of the systems commonly studied in general surgery and present them in a unique format based upon algorithms. The algorithms will begin with the clinical presentation of the patient, work its way through the various diagnostic modalities available to the surgeon, and finally allow the physician to make a decision regarding treatment options based upon various patterns in the algorithms. This text will become a very useful resources for surgeons as it allows complex clinical pathways to be conveniently organized in logical algorithms. It will become a concise yet comprehensive manual to assist in clinical decision making. All algorithms will be reviewed by experts in their field and include the most up-to-date clinical and evidence-based information. Clinical Algorithms in General Surgery provides a useful resource for surgeons in clinical practice as well as surgical residents, and surgical attendings who are preparing for board examinations. See sample algorithm in Attachments.

Author: Patrick Kimuyu
Publisher: GRIN Verlag
ISBN: 3668630658
Category : Medical
Languages : en
Pages : 13

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Book Description
Document from the year 2018 in the subject Medicine - Pathology, grade: 1, Egerton University, language: English, abstract: Hormones play integral biological roles in the body, primarily the regulation of body functions. Scientific research indicates that hormones regulate a range of body functions such as reproduction, metabolism, electrolyte balance, as well as, growth and development. As such, the endocrine system is considered supreme in the regulation of biological processes of the body. Biologically, the endocrine system maintains effective communication among various body organs. This communication ensures homeostasis processes are maintained at constant levels, as well as, enabling the body to respond to changes in the external environment. From anatomical perspective, the endocrine system comprises of glands that are located at different regions of the body, which release hormones. The main components of the endocrine system are the hypothalamus, pituitary gland, thyroid gland, parathyroid gland, adrenal glands, pancreas, and the gonads. These glands release hormones through various regulatory hormonal cascades including the hypothalamic-pituitary-gonadal (HPG) axis, the hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-thyroidal (HPT) axis. As such, any disturbances in the regulatory hormonal cascades results into devastating medical conditions. For instance, disturbances in the HPA axis, primarily excessive release of adrenocorticotropic hormone (ACTH) results into Cushing’s syndrome. Cushing’s syndrome, also known as hypercortisolism is a disorder of the endocrine system that is characterized by excess release of cortisol. Cortisol plays various regulatory functions in all organs and tissues in the body; thus, Cushing’s syndrome affects the entire body. Epidemiological data shows that Cushing’s syndrome affects 10-15 per million people, annually. Therefore, this research paper will provide a comprehensive overview of Cushing’s syndrome. It will discuss the underlying pathology, symptoms, pathophysiology, diagnosis, and treatment of the disorder.

Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004

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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates