A Historical Perspective on Evidence-Based Immunology

A Historical Perspective on Evidence-Based Immunology PDF Author: Edward J. Moticka
Publisher: Newnes
ISBN: 0123983754
Category : Medical
Languages : en
Pages : 396

Get Book Here

Book Description
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. - Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles - Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology - Presents concepts such as the division of lymphocytes into functionally different populations in their historical context - Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

A Historical Perspective on Evidence-Based Immunology

A Historical Perspective on Evidence-Based Immunology PDF Author: Edward J. Moticka
Publisher: Newnes
ISBN: 0123983754
Category : Medical
Languages : en
Pages : 396

Get Book Here

Book Description
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. - Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles - Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology - Presents concepts such as the division of lymphocytes into functionally different populations in their historical context - Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

Systems and Synthetic Immunology

Systems and Synthetic Immunology PDF Author: Shailza Singh
Publisher: Springer Nature
ISBN: 9811533504
Category : Medical
Languages : en
Pages : 273

Get Book Here

Book Description
Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.

From Hippocrates to COVID-19

From Hippocrates to COVID-19 PDF Author: Dale A. Stirling
Publisher: CRC Press
ISBN: 1000574830
Category : Medical
Languages : en
Pages : 589

Get Book Here

Book Description
The COVID-19 pandemic provides stark evidence of the importance of medicine on a global scale. However, revisiting the influenza pandemic of 1918 provided a perspective as we searched for a viable vaccine and instituted public health measures. This shows that medical knowledge is an accumulative process extending to the past and it is in the spirit of that legacy that this bibliography has been compiled. The book is a one-stop resource that cites literature related to the historical aspects of medicine. It also acknowledges medicine’s global reach and devotes significant effort in that respect. Although the online world seems to dominate on both a social and educational level, there is still a need for thoughtfully curated and focused reference works and this bibliography accomplishes that goal. The book has 9,000+ citations. It utilizes the WHO's International classification of Diseases for the section on diseases and disorders and the U.S. Food & Drug Administration's Product Code Classification Database for the section on medical devices, equipment, and instruments. It includes detailed subject, geographuc, and people indexes for an easy reference.

Immunology and Evolution of Infectious Disease

Immunology and Evolution of Infectious Disease PDF Author: Steven A. Frank
Publisher: Princeton University Press
ISBN: 9780691095950
Category : Medical
Languages : en
Pages : 364

Get Book Here

Book Description
Publisher Description

A Silent Fire: The Story of Inflammation, Diet, and Disease

A Silent Fire: The Story of Inflammation, Diet, and Disease PDF Author: Shilpa Ravella
Publisher: W. W. Norton & Company
ISBN: 0393541916
Category : Medical
Languages : en
Pages : 215

Get Book Here

Book Description
“Fascinating.…[Ravella’s writing] breathes life into biological functions.” —Grace Wade, New Scientist A riveting investigation of inflammation—the hidden force at the heart of modern disease—and how we can prevent, treat, or even reverse it. Inflammation is the body’s ancestral response to its greatest threats, the first line of defense it deploys against injury and foreign pathogens. But as the threats we face have evolved, new science is uncovering how inflammation may also turn against us, simmering underneath the surface of leading killers from heart disease and cancer to depression, aging, and mysterious autoimmune conditions. In A Silent Fire, gastroenterologist Shilpa Ravella investigates hidden inflammation’s emerging role as a common root of modern disease—and how we can control it. We meet the visionary nineteenth-century pathologist who laid the foundation for our modern understanding of inflammation, the eccentric Russian zoologist who discovered one of the cells central to our immune system, and the dedicated researchers advancing the frontiers of medical and nutritional science today. With fascinating case studies, Ravella reveals how we can reform our relationships with food and our microbiomes to benefit our own health and the planet’s. Synthesizing medical history, cutting-edge research, and innovative clinical practice, Ravella unveils inflammation as one potential basis for a unifying theory of disease. A paradigm-shifting understanding of one of the most mysterious, buzzed-about topics in medicine and nutrition, A Silent Fire shows us how to live not only long but well.

Mucosal Vaccines

Mucosal Vaccines PDF Author: Hiroshi Kiyono
Publisher: Elsevier
ISBN: 0080537057
Category : Medical
Languages : en
Pages : 501

Get Book Here

Book Description
This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. - Provides the latest views on mucosal vaccines - Applies basic principles to the development of new vaccines - Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases - Unique and user-friendly organization

Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases PDF Author: Hans D. Ochs
Publisher:
ISBN: 019514774X
Category : Medical
Languages : en
Pages : 745

Get Book Here

Book Description
The second edition of Primary Immunodeficiency Diseases presents discussions of gene identification, mutation detection, and clinical and research applications for over 100 genetic immune disorders--disorders featuring an increased susceptibility to infections and, in certain conditions, an icreased rate of malignancies and autoimmune disorders. Since the publication of the first edition, a flurry of new disease entities has been defined and new treatment regimens have been introduced, the most spectacular being successful treatment by gene therapy for two genotypes of combined immunodeficiency. The first edition marked a historic turning point in the field of immunodeficiencies, demonstrating that many of the disorders of the immune systam could be understood at a molecular level. This new edition can proudly document the tremendous pace of progress in dissecting the complex immunologic networks responsible for protecting individuals from these disorders.

Paul's Fundamental Immunology

Paul's Fundamental Immunology PDF Author: Martin Flajnik
Publisher: Lippincott Williams & Wilkins
ISBN: 1975142527
Category : Medical
Languages : en
Pages : 3597

Get Book Here

Book Description
Selected as a Doody's Core Title for 2022! Defining the field of immunology for 40 years, Paul’s Fundamental Immunology continues to provide detailed, authoritative, up-to-date information that uniquely bridges the gap between basic immunology and the disease process. The fully revised 8th edition maintains the excellence established by Dr. William E. Paul, who passed away in 2015, and is now under new editorial leadership of Drs. Martin F. Flajnik, Nevil J. Singh, and Steven M. Holland. It’s an ideal reference and gold standard text for graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role.

The Theory of Endobiogeny

The Theory of Endobiogeny PDF Author: Kamyar M. Hedayat
Publisher: Academic Press
ISBN: 0128173270
Category : Science
Languages : en
Pages : 238

Get Book Here

Book Description
The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia. - Extends the concepts of global systems integrative physiology to practical applications in the clinic - Detailed explanations of historical, exam and biological modeling indexes related to the ANS, corticotropic axis, hepatobiliary and exocrine pancreatic function - Root cause, mechanisms, symptoms and treatments for disorders of immunity, dysbiosis, infectious diseases and spasmophilia, as well as hepatobiliary and pancreatic insufficiency and congestion - Materia medica of 22 key medicinal plants with summary of action and indication of usage according to the theory of Endobigoeny - Special monodiets and dietary suggestions for disorder discussed

Bionanotechnology

Bionanotechnology PDF Author: Anil Kumar Anal
Publisher: CRC Press
ISBN: 1351643630
Category : Medical
Languages : en
Pages : 144

Get Book Here

Book Description
This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.