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Author: Errol C Friedberg
Publisher: World Scientific
ISBN: 9814569062
Category : Biography & Autobiography
Languages : en
Pages : 443
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Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002)This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work.In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest.The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present.This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience.While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Author: Errol C Friedberg
Publisher: World Scientific
ISBN: 9814569062
Category : Biography & Autobiography
Languages : en
Pages : 443
Get Book Here
Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002)This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work.In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest.The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present.This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience.While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Author: Errol C. Friedberg
Publisher: World Scientific Publishing Company
ISBN: 9789814569040
Category : Biochemists
Languages : en
Pages : 0
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Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work. In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest. The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present. This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience. While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Author: George G. Brownlee
Publisher: Cambridge University Press
ISBN: 1316124053
Category : Science
Languages : en
Pages : 315
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Book Description
Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.
Author: Paul Berg
Publisher: CSHL Press
ISBN: 9780879696887
Category : Biography & Autobiography
Languages : en
Pages : 416
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Book Description
George Beadle was a towering scientific figure whose work from the 1930s to 1960 marked the transition from classical genetics to the molecular era. Among other distinctions, he made the pivotal, Nobel Prize–winning discovery with Edward Tatum that the role of genes is to specify proteins. From 1946 to 1960 he led the Caltech Biology Division, rebuilding it to a powerhouse in molecular biology, and afterwards became a successful President of the University of Chicago. This is the first biography of a giant of genetics, written by two of the field's most distinguished contributors, Paul Berg and Maxine Singer.
Author: Joe S. Jeffers
Publisher: Springer
ISBN: 3319547097
Category : Science
Languages : en
Pages : 94
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Book Description
In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
Author: Nicholas Dawidoff
Publisher: Vintage
ISBN: 0307807096
Category : Biography & Autobiography
Languages : en
Pages : 482
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Book Description
NATIONAL BESTSELLER Now a major motion picture starring Paul Rudd “A delightful book that recounts one of the strangest episodes in the history of espionage. . . . . Relentlessly entertaining.”—The New York Times Book Review Moe Berg is the only major-league baseball player whose baseball card is on display at the headquarters of the CIA. For Berg was much more than a third-string catcher who played on several major league teams between 1923 and 1939. Educated at Princeton and the Sorbonne, he as reputed to speak a dozen languages (although it was also said he couldn't hit in any of them) and went on to become an OSS spy in Europe during World War II. As Nicholas Dawidoff follows Berg from his claustrophobic childhood through his glamorous (though equivocal) careers in sports and espionage and into the long, nomadic years during which he lived on the hospitality of such scattered acquaintances as Joe DiMaggio and Albert Einstein, he succeeds not only in establishing where Berg went, but who he was beneath his layers of carefully constructed cover. As engrossing as a novel by John le Carré, The Catcher Was a Spy is a triumphant work of historical and psychological detection.
Author: A. Scott Berg
Publisher: Penguin
ISBN: 1101636416
Category : Biography & Autobiography
Languages : en
Pages : 678
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Book Description
From the #1 New York Times bestselling author, "a brilliant biography"* of the 28th president of the United States. *Doris Kearns Goodwin One hundred years after his inauguration, Woodrow Wilson still stands as one of the most influential figures of the twentieth century, and one of the most enigmatic. And now, after more than a decade of research and writing, Pulitzer Prize–winning author A. Scott Berg has completed Wilson—the most personal and penetrating biography ever written about the twenty-eighth President. In addition to the hundreds of thousands of documents in the Wilson Archives, Berg was the first biographer to gain access to two recently discovered caches of papers belonging to those close to Wilson. From this material, Berg was able to add countless details—even several unknown events—that fill in missing pieces of Wilson’s character, and cast new light on his entire life. From the visionary Princeton professor who constructed a model for higher education in America to the architect of the ill-fated League of Nations, from the devout Commander in Chief who ushered the country through its first great World War to the widower of intense passion and turbulence who wooed a second wife with hundreds of astonishing love letters, from the idealist determined to make the world “safe for democracy” to the stroke-crippled leader whose incapacity—and the subterfuges around it—were among the century’s greatest secrets, from the trailblazer whose ideas paved the way for the New Deal and the Progressive administrations that followed to the politician whose partisan battles with his opponents left him a broken man, and ultimately, a tragic figure—this is a book at once magisterial and deeply emotional about the whole of Wilson’s life, accomplishments, and failings. This is not just Wilson the icon—but Wilson the man. INCLUDES PHOTOGRAPHS
Author: Matthew Cobb
Publisher: Profile Books
ISBN: 1782838031
Category : Medical
Languages : en
Pages : 403
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Book Description
A TIMES ENVIRONMENT AND SCIENCE BOOK OF THE YEAR 2022 'The ideal guide to what is not just a fiendishly complex area of science but also an ethical minefield' Mail on Sunday A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.
Author: Henry T. Greely
Publisher: MIT Press
ISBN: 0262362732
Category : Science
Languages : en
Pages : 396
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Book Description
A leading authority on the scientific, ethical, and legal aspects of genetic biotechnologies asks: What does the birth of gene-edited babies mean—for science and for all of us? “An accessible, clearly written, fact-filled analysis of a new biological frontier.” —The Washington Post In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the cloning of Dolly the sheep was in 1996. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes the experiment and its public rollout (aided by a public relations adviser) but also considers the lessons we can draw from CRISPR'd babies and from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He Jiankui’s experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.
Author: Peter S. Harper
Publisher: Oxford University Press
ISBN: 0190208392
Category : Medical
Languages : en
Pages : 576
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Book Description
An eminent geneticist, veteran author, OMMG Series Editor, and noted archivist, Peter Harper presents a lively account of how our ideas and knowledge about human genetics have developed over the past century from the perspective of someone inside the field with a deep interest in its historical aspects. Dr. Harper has researched the history of genetics and has had personal contact with a host of key figures whose memories and experiences extend back 50 years, and he has interviewed and recorded conversations with many of these important geneticists. Thus, rather than being a conventional history, this book transmits the essence of the ideas and the people involved and how they interacted in advancing- and sometimes retarding- the field. From the origins of human genetics; through the contributions of Darwin, Mendel, and other giants; the identification of the first human chromosome abnormalities; and up through the completion of the Human Genome project, this Short History is written in the author's characteristic clear and personal style, which appeals to geneticists and to all those interested in the story of human genetics.
