Volume 2: Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values: Workshop Summary

Volume 2: Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values: Workshop Summary PDF Author: U. S. Department of Health and Human Services
Publisher: Createspace Independent Pub
ISBN: 9781490324401
Category : Medical
Languages : en
Pages : 42

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Book Description
The Office of Dietary Supplements requested the Tufts Medical Center Evidence-based Practice Center (EPC) to conduct an exercise to identify the issues and challenges of including evidence-based methods as a component of the process used to develop nutrient reference values (such as the Dietary Reference Intakes [DRI]) issued by the Institute of Medicine (IOM). This work was performed under a task order issued by the Agency for Healthcare Research and Quality EPC program. The Tufts EPC assembled a group of nutrition experts from academic institutions and relevant federal government agencies, led participants in teleconferences and meetings, conducted exercises in formulating questions that would be amenable to systematic reviews of the scientific literature, and identified the challenges and limitations of applying this method to processes previously used to establish nutrient reference values. This report summarizes the impetus behind this project, approach taken, and the lessons learned. Nutrient reference values have significant public health and policy implications. This type of dietary guidance is needed for planning diets, assessing the adequacy of diets in individuals and populations, developing nutrition education and guidance, and for setting reference values for nutrition labeling. The IOM Food and Nutrition Board has issued reports on the DRIs for a wide range of nutrients. Six reports have been published and are organized around groups of nutrients. Contents of the reports include a summary of what is known about the nutrient function in the human body, selection of indicators of adequacy of nutrient intakes or nutrient levels, factors that may affect how the nutrients are utilized and that affect requirements, and how nutrients may be related to the prevention of chronic disease across age groups. Various study committees were convened to evaluate a body of available scientific evidence for specific nutrients. Primarily human studies were reviewed and selected animal studies were used when human data are absent or conflicting. Available evidence was weighted according to quality, peer review status, biological plausibility, and whether similar estimates would be derived from different indicators. However, the process of establishing DRIs has been variable and has evolved as experience accrued from study committees. Concern has been expressed that in some cases the methods used to determine DRIs have suffered from a lack of transparency and consistency. Moreover, differences in the reference values derived by various groups of nutrition experts worldwide have been noted for the same nutrient when all presumably have used the same body of available evidence. Given the importance of defining reliable nutrient reference values, there is a need for an explicit, objective, and transparent process to set these values. Evaluating evidence is a major component of informing the process. Because new studies are constantly being published, it would also be desirable to have a framework that allows efficient updating when new information becomes available. Although the mandate to different committees around the world has previously been different, with the globalization of the food supply and health risks it should be expected that evaluating similar evidence will result in similar recommendations. Over the past 15 years, the concept of evidence-based medicine building upon the foundation of systematic reviews, meta-analyses and related methods as important tools for evidence-based practice, has gained widespread acceptance in the evaluation of medical evidence for healthcare decision-making. The application of this approach to evaluating the nutrition literature could provide for the transparent, comprehensive and objective evaluation of scientific evidence and could provide support for a framework for a consistent approach to establishing nutrient reference values for all dietary components.

Volume 2: Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values: Workshop Summary

Volume 2: Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values: Workshop Summary PDF Author: U. S. Department of Health and Human Services
Publisher: Createspace Independent Pub
ISBN: 9781490324401
Category : Medical
Languages : en
Pages : 42

Get Book Here

Book Description
The Office of Dietary Supplements requested the Tufts Medical Center Evidence-based Practice Center (EPC) to conduct an exercise to identify the issues and challenges of including evidence-based methods as a component of the process used to develop nutrient reference values (such as the Dietary Reference Intakes [DRI]) issued by the Institute of Medicine (IOM). This work was performed under a task order issued by the Agency for Healthcare Research and Quality EPC program. The Tufts EPC assembled a group of nutrition experts from academic institutions and relevant federal government agencies, led participants in teleconferences and meetings, conducted exercises in formulating questions that would be amenable to systematic reviews of the scientific literature, and identified the challenges and limitations of applying this method to processes previously used to establish nutrient reference values. This report summarizes the impetus behind this project, approach taken, and the lessons learned. Nutrient reference values have significant public health and policy implications. This type of dietary guidance is needed for planning diets, assessing the adequacy of diets in individuals and populations, developing nutrition education and guidance, and for setting reference values for nutrition labeling. The IOM Food and Nutrition Board has issued reports on the DRIs for a wide range of nutrients. Six reports have been published and are organized around groups of nutrients. Contents of the reports include a summary of what is known about the nutrient function in the human body, selection of indicators of adequacy of nutrient intakes or nutrient levels, factors that may affect how the nutrients are utilized and that affect requirements, and how nutrients may be related to the prevention of chronic disease across age groups. Various study committees were convened to evaluate a body of available scientific evidence for specific nutrients. Primarily human studies were reviewed and selected animal studies were used when human data are absent or conflicting. Available evidence was weighted according to quality, peer review status, biological plausibility, and whether similar estimates would be derived from different indicators. However, the process of establishing DRIs has been variable and has evolved as experience accrued from study committees. Concern has been expressed that in some cases the methods used to determine DRIs have suffered from a lack of transparency and consistency. Moreover, differences in the reference values derived by various groups of nutrition experts worldwide have been noted for the same nutrient when all presumably have used the same body of available evidence. Given the importance of defining reliable nutrient reference values, there is a need for an explicit, objective, and transparent process to set these values. Evaluating evidence is a major component of informing the process. Because new studies are constantly being published, it would also be desirable to have a framework that allows efficient updating when new information becomes available. Although the mandate to different committees around the world has previously been different, with the globalization of the food supply and health risks it should be expected that evaluating similar evidence will result in similar recommendations. Over the past 15 years, the concept of evidence-based medicine building upon the foundation of systematic reviews, meta-analyses and related methods as important tools for evidence-based practice, has gained widespread acceptance in the evaluation of medical evidence for healthcare decision-making. The application of this approach to evaluating the nutrition literature could provide for the transparent, comprehensive and objective evaluation of scientific evidence and could provide support for a framework for a consistent approach to establishing nutrient reference values for all dietary components.

Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values

Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values

Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values PDF Author: Robert Mitchell Russell
Publisher: Department of Health and Human Services Agency Earch and Quality
ISBN: 9781587633805
Category : Food
Languages : en
Pages : 33

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Book Description


Today’s Nutrition and Tomorrow’s Public Health: Challenges and Opportunities

Today’s Nutrition and Tomorrow’s Public Health: Challenges and Opportunities PDF Author: Irene Lenoir-Wijnkoop
Publisher: Frontiers Media SA
ISBN: 2889198189
Category : Science (General)
Languages : en
Pages : 85

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Book Description
At the dawn of the third millennium, we are confronted with a disturbing phenomenon: although global life expectancy still increases, this is not the case for healthy life expectancy! The explanation of this seemingly contradiction is mainly due to the rising prevalence of the new pandemia of chronic non-communicable diseases (NCDs). Even in low and middle income countries, the improvement in healthcare status and life expectancy is paralled by the increase of NCDs, as in all countries worldwide. Since the United Nations General Assembly held in New York in 2011, many publications have emphasized the close link between NCDs and nutrition. The NCDs epidemic forces us to reconsider the public health perspectives. Many governments, non-governmental organizations and other institutions are actively involved in educational nutrition programs and campaigns; however their efforts seldom obtain the results hoped for. It is extremely difficult to induce changes in lifestyle and behavior that have built up over a long period of time. However, it becomes urgent to adapt to our changing life-environment where traditional wisdom and intuitive choices are giving way to individual thinking and search for (often uncontrolled) information. This engenders a number of unprecedented challenges and it calls for a re-appraisal of the existing paradigms to achieve an adequate management of the upstream determinants of health instead of a (pre)dominant medical and hospital-centric approach. In the era of personalized healthcare, it is time to empower policy makers, professionals and citizens for achieving an evidence-based change in the health-disease interface and decision-making process for public health interventions. The scientific and professional society Health Technology Assessment International (HTAi) has recognized nutrition as a health technology (preventative) by creating a Interest Group (IG) dedicated to research on methodologies and assessments of nutrition-related public health, while taking into account contextual factors (ethical, legal, social, organizational, economic, …) in order to generate meaningful outcomes for establishing evidence-based health policies. This Research Topic aims to elaborate on some of the potential hurdles or guarantees which have to be overcome for the sake of sustainable healthcare provisions anywhere in the world, such as shortcomings in methodological approaches, regulatory frameworks, gaps between evidence, its hierarchy and final recommendations for public health management.

Nutrition in Lifestyle Medicine

Nutrition in Lifestyle Medicine PDF Author: James M. Rippe
Publisher: Humana Press
ISBN: 3319430270
Category : Medical
Languages : en
Pages : 444

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Book Description
This newest addition to the Nutrition and Health series focuses on nutrition’s key role in lifestyle interventions to prevent and manage diseases. The book pays particular attention to nutritional considerations related to obesity, diabetes, and cardiovascular disease. Edited by cardiologist, Dr. James Rippe, a well-known expert in the nascent specialty of Lifestyle Medicine, Nutrition in Lifestyle Medicine will also focus on a variety of specialized areas such as nutrition for athletes and physically active individuals, hydration, and nutrition throughout the life cycle (spanning from children to individuals over the age of 60). In addition, chapters will be included on controversies in nutrition, such as health effects of added sugars and saturated fatty acids in the diet. Finally, specialized chapters will be included in such areas as nutrition for women, nutrition for men, nutrition for latinos, the use of supplements, communication about nutrition, public policy issues, and the interface between nutrition and physical activity. Lifestyle Medicine, supported by the American Journal of Lifestyle Medicine, Dr. Rippe’s textbook Lifestyle Medicine (CRC Press, 2013) and American College of Lifestyle Medicine (ACLM), is a new national medicine specialty that stresses the use of lifestyle interventions in the treatment and management of disease. Its practitioners effectively manage medical treatments alongside the lifestyle interventions, for example lowering insulin treatment for patients with diabetes, reducing the dose of anti-hypertension medications for people with hypertension, and prescribing certain medical interventions that aid in smoking cessation.

Assessing the Evidence in Indigenous Education Research

Assessing the Evidence in Indigenous Education Research PDF Author: Nikki Moodie
Publisher: Springer Nature
ISBN: 303114306X
Category : Education
Languages : en
Pages : 303

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Book Description
This book explores the current state of research on Indigenous education in Australia. In particular, these chapters focus on exploring deep and enduring questions about the failures of schooling to address the needs of Aboriginal communities. This book provides a systematic analysis of existing research to explain how connection to culture - and the recognition of Indigenous sovereignties and knowledges - are the keys to Aboriginal excellence in schooling.

Experimental IR Meets Multilinguality, Multimodality, and Interaction

Experimental IR Meets Multilinguality, Multimodality, and Interaction PDF Author: K. Selçuk Candan
Publisher: Springer Nature
ISBN: 3030852512
Category : Computers
Languages : en
Pages : 487

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Book Description
This book constitutes the refereed proceedings of the 12th International Conference of the CLEF Association, CLEF 2021, held virtually in September 2021. The conference has a clear focus on experimental information retrieval with special attention to the challenges of multimodality, multilinguality, and interactive search ranging from unstructured to semi structures and structured data. The 11 full papers presented in this volume were carefully reviewed and selected from 21 submissions. This year, the contributions addressed the following challenges: application of neural methods for entity recognition as well as misinformation detection in the health area, skills extraction in job-match databases, stock market prediction using financial news, and extraction of audio features for podcast retrieval. In addition to this, the volume presents 5 “best of the labs” papers which were reviewed as full paper submissions with the same review criteria. 12 lab overview papers were accepted and represent scientific challenges based on new data sets and real world problems in multimodal and multilingual information access.

P2-12-03 - Systematic Reviews as Part of the Evidence-based Framework in Nutrition and Dietetics: Implementation, Challenges, and Future Directions

P2-12-03 - Systematic Reviews as Part of the Evidence-based Framework in Nutrition and Dietetics: Implementation, Challenges, and Future Directions PDF Author: Elizabeth Neale
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description
Policy and practice in nutrition and dietetics is based on current available scientific evidence. However, the discipline faces an increasing volume of misinformation and pseudo-science relating to nutrition. This presents a challenge to the nutrition research community and practitioners alike, as well as consumers. It highlights the need to critically examine the current evidence-based framework in nutrition, and identify strategies for future improvements. We describe the use of systematic reviews as part of the current evidence-based framework in the nutrition field, and discuss challenges and opportunities relating to policy and guideline development. Undertaking systematic reviews is part of the methodology underpinning the evidence-based framework. These reviews form the basis for implementation documents in public health such as dietary guidelines and nutrient reference values. Assuring the quality of systematic reviews is an important priority. Recommendations for practitioners and consumers emerge following these reviews on consumption of nutrients, foods, and whole diets; however an ongoing challenge is ensuring these resources are updated regularly to remain timely and accurate. Another application of systematic reviews is for substantiation of health claims made on food packaging and other forms of nutrition related messaging. These may support the marketing of food products, so it is important to evaluate the strength and quality of the evidence that supports these claims. In this case, a lack of external oversight of self-substantiation of claims may increase the risk that claims are misused or are inaccurate. Collecting, synthesizing, and translating the evidence base in nutrition remains an imperative task for those working in the food and nutrition domain. This is particularly seen in light of the increasing volume of misinformation encountered by consumers and the growing problem of lifestyle related disease associated with poor diet. Nutrition researchers, policy makers and practitioners need to work together effectively to ensure timely, efficient, and relevant collection, synthesis, and implementation of the evidence base. To ensure informed and robust nutrition policy, research, and practice into the future, consistent and rigorous approaches to systematic review, regular updates and effective oversight is required.Conflict of interest:There is no conflict of interest.

Harmonizing the Process for Establishing Nutrient Reference Values

Harmonizing the Process for Establishing Nutrient Reference Values PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309685052
Category : Medical
Languages : en
Pages : 49

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Book Description
Harmonized approaches to setting recommendations for safe and appropriate dietary intakes and nutritional interventions are critical to support the resolution of differences across countries in setting national and international nutrition standards; promote consistency in public and clinical health objectives; provide a mechanism for designing national and international food and nutrition policies; and enhance the transparency of national standards for trade and other regulatory actions that have economic, health, and safety implications. Consistent dietary intake recommendations cannot be made without first establishing a consistent approach to derive reference values for population-level nutrient intakes. This tool kit is designed to help global stakeholders, including those in low- and middle-income countries, participate more easily in the process of implementing, disseminating, and evaluating a consistent and homogeneous methodological approach to the nutrient reference value process.

Harmonization of Approaches to Nutrient Reference Values

Harmonization of Approaches to Nutrient Reference Values PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309477727
Category : Medical
Languages : en
Pages : 175

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Book Description
Recommended intake levels for nutrients and other dietary components were designed initially to prevent nutrient deficiency diseases in a given population, and the original methodological approach used to derive intake values did not include consideration for other applications. However, with the increasing globalization of information and the identification of a variety of factors specific to different population subgroups (e.g., young children and women of reproductive age) that influence their nutritional needs, there has been increasing recognition of the need to consider methodological approaches to deriving nutrient reference values (NRVs) that are applicable across countries and that take into account the varying needs of different population subgroups. There is a need for guidance and recommendations about methodological approaches, as well as their potential for application to an international process for the development of NRVs, and particularly for young children and women of reproductive age. Harmonization of Approaches to Nutrient Reference Values: Applications to Young Children and Women of Reproductive Age examines these issues and makes recommendations for a unified approach to developing NRVs that would be acceptable globally.