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Author: Udo Dunzendorfer
Publisher: Springer Science & Business Media
ISBN: 9783764362553
Category : Architecture
Languages : en
Pages : 216
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Book Description
This drug is a landmark discovery, which consequently has become the definitive therapy for the treatment of erectile dysfunction (ED). Following the major breakthrough in the field of nitric oxide (NO)-physiology and pharmacology leading to sildenafil being marketed, the most current information is presented in this reference book, including ongoing research from several disparate groups about NO as endothelium-derived relaxing factor (EDRF) and also as a neurotransmitter for nerves innervating erectile tissue in mammals. The development of sildenafil as an oral phosphodiesterase-5 (PDE5) inhibitor drug for the treatment of ED resulted in one of the first products, which made its way successfully from basic NO research to routine clinical therapy. This volume addresses all fields of sildenafil application in both men and women. In a highly competitive research environment with a critical medical need for drug improvements the reader will learn more about clinical resistance to sildenafil treatment and the modalities to overcome the failure rates. The individual chapters cover clinical use, pharmacokinetics, pharmacodynamics, biochemistry, and cultural aspects. They are written by leading experts in their respective fields. Therefore, readers a?? whether professionals in the pharmaceutical industry, physicians treating ED, biochemists, chemists or pharmacologists a?? will find a detailed and up-to-date knowledge base about current research activities and an excellent overview for further research on this compound class and its cultural impact.
Author: Udo Dunzendorfer
Publisher: Springer Science & Business Media
ISBN: 9783764362553
Category : Architecture
Languages : en
Pages : 216
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Book Description
This drug is a landmark discovery, which consequently has become the definitive therapy for the treatment of erectile dysfunction (ED). Following the major breakthrough in the field of nitric oxide (NO)-physiology and pharmacology leading to sildenafil being marketed, the most current information is presented in this reference book, including ongoing research from several disparate groups about NO as endothelium-derived relaxing factor (EDRF) and also as a neurotransmitter for nerves innervating erectile tissue in mammals. The development of sildenafil as an oral phosphodiesterase-5 (PDE5) inhibitor drug for the treatment of ED resulted in one of the first products, which made its way successfully from basic NO research to routine clinical therapy. This volume addresses all fields of sildenafil application in both men and women. In a highly competitive research environment with a critical medical need for drug improvements the reader will learn more about clinical resistance to sildenafil treatment and the modalities to overcome the failure rates. The individual chapters cover clinical use, pharmacokinetics, pharmacodynamics, biochemistry, and cultural aspects. They are written by leading experts in their respective fields. Therefore, readers a?? whether professionals in the pharmaceutical industry, physicians treating ED, biochemists, chemists or pharmacologists a?? will find a detailed and up-to-date knowledge base about current research activities and an excellent overview for further research on this compound class and its cultural impact.
Author: Larry Katzenstein
Publisher:
ISBN: 9780966371314
Category : Health & Fitness
Languages : en
Pages : 132
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Book Description
Author: Robert Whitescarver
Publisher:
ISBN: 9781934368459
Category :
Languages : en
Pages : 300
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Book Description
Robert Whitescarver and his wife Jeanne live on a cattle farm in Swoope, Va. in the Shenandoah Valley. Whitescarver's stories and journal entries tell tales of combining good farming and good conservation practices on a life journey that has produced a healthier ecosystem and a cleaner Chesapeake Bay. You will laugh and cry as you travel into a world of wide open spaces, shrikes, calf cookers, riparian buffers, and cow pies.
Author: Ruben Vardanyan
Publisher: Academic Press
ISBN: 0124115241
Category : Medical
Languages : en
Pages : 870
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Book Description
Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation
Author: Charles D. Ciccone
Publisher: F.A. Davis
ISBN: 0803640048
Category : Medical
Languages : en
Pages : 1217
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Book Description
A one-of-a-kind guide specifically for rehabilitation specialists! A leader in pharmacology and rehabilitation, Charles Ciccone, PT, PhD offers a concise, easy-to-access resource that delivers the drug information rehabilitation specialists need to know. Organized alphabetically by generic name, over 800 drug monographs offer the most up-to-date information on drug indications, therapeutic effects, potential adverse reactions, and much more! A list of implications for physical therapy at the end of each monograph helps you provide the best possible care for your patients. It’s the perfect companion to Pharmacology in Rehabilitation, 4th Edition!
Author: P. Needleman
Publisher: Springer Science & Business Media
ISBN: 364266024X
Category : Medical
Languages : en
Pages : 206
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Book Description
Nitroglycerin and other organic nitrates have been used for over a century in the treatment of angina pectoris. Millions of patients, throughout the world, have placed nitroglycerin tablets under the tongue and have experienced rapid and dramatic relief from the chest pain that frequently occurs as a manifestation of disease of the coronary arteries. The empirical observation of the safe use of nitrates for tile alleviation of the symptoms of angina have led to their widespread medical acceptance. The use of organic nitrates preceded any knowledge of their mechanism of action or their ultimate metabolic fate. Thus, more simply stated, although sub lingual nitrates helped the patients, little was known concerning what these drugs do to the body or what the body does to the drugs. A substantial number of investigators have focused on these questions especially during the last two decades. We now have considerably more insight into the pathways of degradation of organic nitrates and the relationship of the metabolic processes to the biological action of these agents. Similarly, considerable effort has been expended in understanding the mechanism of action of these agents directly on vascular smooth muscle and on cardiac work and performance. Finally, there is a more substantive understanding of the physiology of the coronary circulation as well as the" pathophysiologic manifestations of myocardial disease.
Author: Tony Guerra
Publisher: Lulu.com
ISBN: 1329898443
Category : Science
Languages : en
Pages : 242
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Book Description
As a working parent of 4-year-old triplet daughters, I understand time management presents one of the greatest barriers to my pharmacology students' success. Many students feel that cold sense of overwhelm and information overload. This easy-to-read guide organizes pharmacology into manageable, logical steps you can fit in short pockets of time. The proven system helps you memorize medications quickly and form immediate connections. With mnemonics from students and instructors, you'll see how both sides approach learning. After you've finished the 200 Top Drugs in this book, reading pharmacology exam questions will seem like reading plain English. You'll have a new understanding of pharmacology to do better in class, clinical and your board exam. You'll feel the confidence you'd hoped for as a future health professional. For patients and caregivers, this book provides a means to memorize medications to quickly and articulately communicate with your health providers.
Author: Thorsteinn Loftsson
Publisher: Academic Press
ISBN: 0128014911
Category : Medical
Languages : en
Pages : 179
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Book Description
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. - Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products - Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes - Illustrates how to write and evaluate drug registration files
Author: Kshipra Misra
Publisher: Academic Press
ISBN: 0128140003
Category : Science
Languages : en
Pages : 350
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Book Description
Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development. - Provides the recent advances and potential therapeutic agents for ameliorating the high-altitude complications - Includes herbal remedies for the prophylaxis and treatment of the high-altitude maladies - Elucidates the significance of Yogic practices and ergonomics in managing stress at high altitude
Author: Meika Loe
Publisher: NYU Press
ISBN: 0814752004
Category : Business & Economics
Languages : en
Pages : 301
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Book Description
Drawing on interviews with men who take the drug, their wives, doctors and pharmacists as well as scientists and researchers in the field, this fascinating account provides an intimate history of the Viagra's effect on America.
