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Author: J. Aschoff
Publisher: Springer Science & Business Media
ISBN: 3642686516
Category : Science
Languages : en
Pages : 376
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Book Description
Author: J. Aschoff
Publisher: Springer Science & Business Media
ISBN: 3642686516
Category : Science
Languages : en
Pages : 376
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Book Description
Author: Deutsche Forschungsgemeinschaft
Publisher:
ISBN:
Category :
Languages : en
Pages : 363
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Book Description
Author: Vinod Kumar
Publisher: Springer Science & Business Media
ISBN: 366206085X
Category : Science
Languages : en
Pages : 268
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Book Description
(Chapters 11 to 14) summarise important features of the biological clock at the level of whole animal covering all vertebrate classes (fish to mammal). Chapters 15 and 16 are on long term (seasonal) rhythms in plants and higher vertebrates. Short term rhythms (ultradian rhythms), the significance of having a clock system in animals living in extreme (arctic) environments, and the diversity of circadian responses to melatonin, the key endocrine element involved in regulation of biological rhythms, have been discussed in Chapters 17 to 19. Finally, a chapter on sensitivity to light of the photoperiodic clock is added which, using vertebrate examples, illustrates the importance of wavelength and intensity of light on circadian and non-circadian functions. A well-known expert writes each chapter. When presenting information, the text provides consistent thematic coverage and feeling for the methods of investigation. Reference citation within the body of the text adequately reflects the literature as subject is developed. A chapter begins with an abstract that enables a reader to know at the first glance the important points covered in that chapter. The chapter concludes with a full citation of references included in the text, which could be useful for further reading. The book ends with a comprehensive subject index that may be useful for quick searches.
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470090820
Category : Science
Languages : en
Pages : 306
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Book Description
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary feature of these biological clocks is their ability to entrain to environmental stimuli. The dominant stimulus comes from environmental light cues, which requires the existence of photopigments sensitive to light. The exact identity of the molecules involved in circadian photoreception has remained elusive. The classical view of the circadian system is of diverse physiological rhythms regulated by a centralized clock structure. This book presents evidence that challenges this view. Experiments in both vertebrate and invertebrate systems demonstrate that the circadian timing system is dispersed throughout the animal and suggest that possibly every cell contains an autonomous clock mechanism. A variety of tissues and cells contain have been shown to maintain an oscillation when placed in vitro and removed from any external cues or signals that originate from the classical clock structures and/or the environment. This book draws together contributions from an international and interdisciplinary group of experts whose work is focused on all aspects of the topic. Coverage includes the mechanisms of light signalling to the vertebrate clock, the connections between central and peripheral clocks, circadian gene expression patterns and output pathways of clock mechanisms.
Author: Raúl Aguilar-Roblero
Publisher: Springer
ISBN: 3319089455
Category : Medical
Languages : en
Pages : 396
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Book Description
Well known experts in the field of Chronobiology from around the world, provide an integrative view of the state of the art of circadian biology. At present, genetic and epigenetic interaction of regulatory pathways among circadian oscillators, metabolic networks, cellular differentiation and neuronal communication are subject of intense scrutiny. The book is organized in three sections: The first includes selected examples of the circadian systems of crustaceans, insects, fish, birds and mammals. The second is a detailed view of the physiological mechanisms underlying the circadian clocks in mammals. Finally, in the third section some examples of the relevance of circadian biology and circadian misalignment to health and disease are provided including nutrition and metabolism, obesity, cancer, cardiovascular and pulmonary diseases, Huntington and affective diseases. This section concludes with a brief review on gene therapy and its potential use as a therapeutic tool to correct “clock genes” pathologies. This book is aimed at all those interested in contemporary aspects of physiology, biochemistry and molecular biology applied to the study and characterization of timing systems.. It could be used as an initial approach to this field, but it also provides updated information for those already familiar with the fascinating field of Chronobiology.
Author: Milton H. Stetson
Publisher: Springer Science & Business Media
ISBN: 1461237408
Category : Science
Languages : en
Pages : 265
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Book Description
In just one concise and lucidly written volume a multitude of topics is covered introducing the results of extensive research on the processing of environmental information in vertebrates. Practical examples are provided to illustrate points made in the text. Many factors, both from the external environment and from within the animals own cells or tissue makeup can directly serve as a pressure to elicit physiological and/or behavioral responses in the organisms studied. Light intensity, photoperiod, circadian rhythms, seasonal variation and daylenght, just to name a few, are among the environmental factors that are correlated in these studies to behavioral or hormonal changes, organ function, and reproduction. This work will serve as a guidebook and easy reference source for students and research professionals in physiology, endocrinology, comparative zoology, and veterinary science.
Author: Maria Luisa Fanjul-Moles
Publisher:
ISBN: 9788178953298
Category :
Languages : en
Pages : 203
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Book Description
Chronobiology is the study of adaptations evolved at all levels of organization by living organisms to cope with regular geophysical cycles in the environment. The Earth s rotation originates alternation of light and darkness with a 24-h period; this signal allowed primordial organisms to keep track of time, adjust their internal temporal order, and anticipate external time. This capability fostered the development in living matter of endogenous temporal organization of cellular process over an approximately 24-h period. The cellular machinery that generates this ability is known as the biological clock, and its outputs as circadian rhythms. Such clocks can be found in nearly all organisms, from simple bacteria to insects, mammals, and of course, humans. The selective advantage conferred to all organisms by the biological clock comprises coordination of molecular, physiological, and behavioral processes, so as to ensure its occurrence during the daily cycle s optimal time. When organisms are maintained in an environment with strong time signals (zeitgebers) such as the light-dark cycle, each of their circadian rhythms establishes a stable relationship with each other and with the external cycle, and becomes an entrained system. Different species and different individuals within each species are coupled with their own typical phases to the natural 24-h cycle. Thus, time is embedded in our genes, and circadian clocks have emerged several times during evolution as a result of convergence to meet a common need. And although key proteins are not conserved, all clocks known to date in eukaryotes involve transcriptional-translational feedback loops. Over the last decades, chronobiology has expanded enormously, is emerging independently in many fields, and it is one of the most interdisciplinary fields in biology. While it has not been easy to understand how a biological clock works in an organism, research with different models from single-cell organisms to complex multicellular plants and animals have provided us insight concerning the ticking of the clock. Identification of circadian rhythms in biochemical and behavioral parameters in different unicellular organisms, localization of different oscillators in combination with behavioral outputs markers by neurobiological techniques in insects and mammals, as well as molecular genetics that has led to identification and cloning of clock genes in several species including humans have rendered chronobiology a diverse and dynamic discipline, with not only biological relevance but also important social and medical implications. Our goal in editing this book was to provide a comparative view of our current knowledge regarding circadian rhythms and clocks at different phylogenetic levels. The authors contributing to this volume review both circadian molecules and mechanisms in representative groups ranging from simple organisms as unicells to complex ones such as invertebrates and non-mammal and mammal vertebrates. The book reflects and is a token of different approaches to the field, such as regulation molecules and their biochemical pathways involved in either circadian or exogenous aspects of the rhythmic process and its regulation in photoautotrophic unicells and the neurobiological and molecular bases of circadian oscillators in some invertebrates and vertebrates. A number of works are focused in the importance of environmental, social, and nutrient temporal signals as synchronizing agents in insects and in different vertebrate models. These reviews are not only centered on the adult organism at the integrative level, but also provide an ontogenetic view at behavioral, physiological, and molecular levels. Furthermore, they supply evidence on several organs as potential sources of circadian signaling for different vertebrate groups, which indicates multioscillatory circadian systems similar to those proposed for some invertebrates. In Chapter 1, Rüdiger Hardeland revises the importance of tryptophan metabolic pathways in two unicells, Euglena gracilis, and the dinoflagellate, Lingulodinium polyedrum. Barbara-Ann Battelle, in Chapter 2, reviews and describes current knowledge of the circadian system of a Chelicerata, Limulus polyphemus, visual inputs into the central clock, and efferent pathways of the clock to the eyes, in addition to the molecular mechanisms underlying these processes. In Chapter 3, María Elena Durán-Lizárraga et al. review the role of different crustacean neuropeptides in the regulation of several physiological processes, such as those proposed as controlled by the circadian system of decapoda, particularly in crayfish. Claudio R. Lazzari and Teresita C. Insausti examine, in Chapter 4, the importance of circadian rhythms from insect s populations, closely associated with the history of chronobiology and the Pittendrigh pioneering work. Continuing on insects, the concept of the superorganism and the interaction of rhythms at different frequencies in different cohorts of individuals forming a colony is presented in Chapter 5 by Mirian David-Marques and Cintia Etsuko-Yamashita. In dealing with vertebrates, Raquel Carvalho and Luiz Menna-Barreto in Chapter 6 address fish from the phenomenology of circadian rhythms to the description of the underlying multioscillatory system, finally reviewing its ecological and evolutionary relevance of these species as a model. The following chapter (7) by Carolina Escobar et al. offers an integrative view of the so-called food-entrained oscillator in rodents. Then, in Chapter 8 Ivette Caldelas and colleagues provide us with an ontogenetic approach to non-visual entrainment of the circadian system, an alternative view of the food-entrained oscillator, using as a natural model the newborn rabbit. Still in the area of restricted food availability as an entraining signal, in Chapter 9 Adrián Báez-Ruíz et al. provide yet another perspective of this phenomenon, which stresses the role of liver physiology and biochemistry in the regulation of food ingestion and hepatic circadian rhythmicity. Finally, in Chapter 10 Raúl Aguilar-Roblero and colleagues review the role of the rodent suprachiasmatic nuclei as a biological clock for the mammalian circadian system, with emphasis on molecular and cellular aspects involved in the first steps of coding biological time into a signal readable by its neuronal targets. We have attempted to provide a panoramic perspective of the multiple approaches for addressing the study of the circadian system in different organisms. Selection of contributions included certain aspects of circadian rhythms not easily found in other reviews. We are indebted to the enthusiastic response of the entire group of contributors, all distinguished professors from universities from different countries, in achieving publication of this volume. We hope readers will find the text useful and that it will perhaps further promote their interest in this area of biology.
Author: Pavol Svorc
Publisher: BoD – Books on Demand
ISBN: 1789849004
Category : Medical
Languages : en
Pages : 109
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Book Description
The regular alternation of light and dark affects not only human biological systems, but also the social organization of behavior. The effect of such light modes is manifested in periodic changes in physiological functions and biological rhythms exhibited at every level of life. The book discusses some of the specificities of the circadian rhythms in living organisms and mentions aspects of the control of circadian rhythms as well as experimental and clinical cases that are closely related to circadian disruption. This book can evoke interest in many researchers who want to use this information for the advancement of their research towards a better understanding of the biological time structure.
Author: Joseph S. Takahashi
Publisher: Springer Science & Business Media
ISBN: 9780306465048
Category : Medical
Languages : en
Pages : 820
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Book Description
The nature of the circadian clocks is described at the molecular, cellular, tissue, and system levels of organization in diverse organisms. The central role of the circadian clock in the regulation of the sleep-wake cycle as well as seasonal rhythms and other cyclical processes is also discussed. The importance of the circadian clock system for human health, safety, performance, and productivity is also reviewed in this volume."--BOOK JACKET.
Author: D.L. Denlinger
Publisher: Gulf Professional Publishing
ISBN: 044450608X
Category : Science
Languages : en
Pages : 245
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Book Description
Now that many of the clock genes have been identified it is possible to track daily patterns of clock-related mRNAs and proteins to link the entraining light cycles with molecular oscillations within the cell. Insect experiments have led the way in demonstrating that the concept of a "master clock" can no longer be used to explain the temporal organization within an animal. Insects have a multitude of cellular clocks that can function independently and retain their function under organ culture conditions, and they thus offer a premier system for studying how the hierarchical organization of clocks results in the overall temporal organization of the animal. Photoperiodism, and its most obvious manifestation, diapause, does not yet have the molecular underpinning that has been established for circadian rhythms, but recent studies are beginning to identify genes that appear to be involved in the regulation of diapause.