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Author:
Publisher:
ISBN: 9789461824905
Category :
Languages : en
Pages : 139
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Book Description
"Non-invasive evaluation of the cerebral blood flow (CBF) by means of arterial spin labeling (ASL) MRI offers an interesting alternative to currently used clinical perfusion measurement techniques. Where the current perfusion imaging techniques require the injection of an exogenous contrast-agent, ASL employs the blood that travels to the brain tissue as an endogenous tracer, for a non-invasive evaluation. However, due to the limited image quality and reliability of ASL measurements, the application of ASL was predominantly limited to highly specialized MRI centers. Recent technical developments in ASL research have elevated the quality and reliability of the technique to a level where it is ready for widespread ASL usage in clinical and research applications. However, with the focus mainly on technical improvements, several clinically relevant aspects such as patient comfort and quantitative performance have not been fully investigated to date. The main aim of this thesis was therefore to investigate such clinically relevant aspects. The chapters in this thesis address a few of the important steps necessary into making ASL a clinically accepted technique for use in daily clinical practice. Where chapters 2 and 3 focus on improving patient comfort, chapters 4 to 6 address the performance of different ASL techniques with respect to the gold-standard perfusion measurement."--Samenvatting auteur.
Author:
Publisher:
ISBN: 9789461824905
Category :
Languages : en
Pages : 139
Get Book Here
Book Description
"Non-invasive evaluation of the cerebral blood flow (CBF) by means of arterial spin labeling (ASL) MRI offers an interesting alternative to currently used clinical perfusion measurement techniques. Where the current perfusion imaging techniques require the injection of an exogenous contrast-agent, ASL employs the blood that travels to the brain tissue as an endogenous tracer, for a non-invasive evaluation. However, due to the limited image quality and reliability of ASL measurements, the application of ASL was predominantly limited to highly specialized MRI centers. Recent technical developments in ASL research have elevated the quality and reliability of the technique to a level where it is ready for widespread ASL usage in clinical and research applications. However, with the focus mainly on technical improvements, several clinically relevant aspects such as patient comfort and quantitative performance have not been fully investigated to date. The main aim of this thesis was therefore to investigate such clinically relevant aspects. The chapters in this thesis address a few of the important steps necessary into making ASL a clinically accepted technique for use in daily clinical practice. Where chapters 2 and 3 focus on improving patient comfort, chapters 4 to 6 address the performance of different ASL techniques with respect to the gold-standard perfusion measurement."--Samenvatting auteur.
Author: Richard B. Buxton
Publisher: Cambridge University Press
ISBN: 1139481304
Category : Medical
Languages : en
Pages : 479
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Book Description
Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.
Author: J. P. Schadé
Publisher:
ISBN: 9780444409522
Category : Brain
Languages : en
Pages : 438
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Book Description
Author: Peter B. Barker
Publisher: Cambridge University Press
ISBN: 1107013399
Category : Medical
Languages : en
Pages : 373
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Book Description
This concise and comprehensive review uniquely contains all the information required to perform and interpret clinical MR perfusion imaging.
Author: Alison M. Campbell
Publisher:
ISBN:
Category : Blood flow
Languages : en
Pages : 202
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Book Description
Author: Michael Chappell
Publisher: Oxford University Press
ISBN: 0198793812
Category : Medical
Languages : en
Pages : 157
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Book Description
ASL is an increasingly popular tool to study the brain. The aim of this primer is to equip someone new to the field with the knowledge to make informed choices about ASL acquisition and analysis. While providing a stand-alone introduction to this subject, the text can be read with others in the series for a comprehensive overview of neuroimaging.
Author:
Publisher:
ISBN: 9789461825421
Category :
Languages : en
Pages : 235
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Book Description
Author: Sebastien Ourselin
Publisher: Springer
ISBN: 3319467263
Category : Computers
Languages : en
Pages : 666
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Book Description
The three-volume set LNCS 9900, 9901, and 9902 constitutes the refereed proceedings of the 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016, held in Athens, Greece, in October 2016. Based on rigorous peer reviews, the program committee carefully selected 228 revised regular papers from 756 submissions for presentation in three volumes. The papers have been organized in the following topical sections: Part I: brain analysis, brain analysis - connectivity; brain analysis - cortical morphology; Alzheimer disease; surgical guidance and tracking; computer aided interventions; ultrasound image analysis; cancer image analysis; Part II: machine learning and feature selection; deep learning in medical imaging; applications of machine learning; segmentation; cell image analysis; Part III: registration and deformation estimation; shape modeling; cardiac and vascular image analysis; image reconstruction; and MR image analysis.
Author: Michael Chappell
Publisher: Oxford University Press
ISBN: 0192512579
Category : Science
Languages : en
Pages : 157
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Book Description
Arterial Spin Labeling (ASL) is an increasingly popular tool to study the brain. What sets it apart from other neuroimaging methods is the combination of quantitative measurements of a physiologically well-defined process, namely perfusion, and a completely non-invasive acquisition methodology. Cerebral perfusion is a critical component to brain health, as it is the primary means to deliver nutrients to support brain function as well as clearing waste products. Hence it is a useful quantity to study in disease where changes in perfusion can indicate regions of the brain that are pathological. Likewise changes in perfusion can be indicative of greater demand for nutrients, such as might be required in response to an increase in neuronal activity. With the advent of a consensus by the ASL community on good practice and a recommendation on robust methods for ASL data collection, more and more researchers are now able to access and use ASL. Despite the technological advances, ASL remains a technique with a low signal to noise ratio. This makes the wise choice of the appropriate analysis methods more important. The aim of this primer is to equip someone new to the field of perfusion imaging and ASL with the knowledge not only to make good choices about ASL acquisition and analysis, but also to understand what choices they are making and why. Examples of analysis applied to real data are given throughout the text and instructions on how to reproduce the analyses are illustrated on the primer website. Written to provide a stand-alone introduction to perfusion qualification using ASL, this primer also works with other texts in the Oxford Neuroimaging Primers series to provide a comprehensive overview of the increasingly influential field of neuroimaging.
Author: Nicole Seiberlich
Publisher: Academic Press
ISBN: 0128170581
Category : Computers
Languages : en
Pages : 1094
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Book Description
Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
