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Author: Jorge Ernesto Jimenez
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Dynamic contrast enhanced (DCE) MRI is the most sensitive imaging technique for detecting breast cancer. Unfortunately, breast DCE MRI is primarily recommended in patients at high risk for breast cancer. As a result, relatively few women benefit from breast MRI. Shortening MR breast imaging protocols is a key requirement to reduce cost and improve patient access to this powerful imaging tool for the detection of breast cancer. We developed a new technology for bilateral breast imaging that learns and models temporal behaviors through a local low rank (LLR) constraint that differs from previous approaches in breast MR iterative image reconstruction. We present an imaging methodology that delivers simultaneously higher spatial and temporal resolution than any previously published methods and a robust technology whose performance does not depend on lesion size, morphology or heterogeneity. Furthermore, we adopt an early enhancement phase approach which provides similar or more valuable information than the current methodology with a much shorter scan time. We present an ultra-fast (10 s) volumetric bilateral breast MRI exam with 0.8 mm isotropic resolution, surpassing today's standard clinical resolution while providing temporal resolutions six-to-eighteen-fold faster. By simultaneously providing high spatial and temporal information of the brief but important early enhancement phase, we provide clinicians and researchers with the capability to extract all the diagnostic and lesion characterization data possible from early enhancement phase. The goal for this project was to develop and demonstrate the feasibility of a high-performance sequence for abbreviated breast MRI. Though numerous accelerated methods have previously been proposed, very little validation of the information they derive has been generated due to the complexity of testing reconstruction methods and lesion-dependent imaging performance without a reference standard for comparison. We validated the effectiveness of the method to create high temporal fidelity in a digital phantom and demonstrated the feasibility of our proposed approach with 11 clinical subjects.
Author: Jorge Ernesto Jimenez
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Dynamic contrast enhanced (DCE) MRI is the most sensitive imaging technique for detecting breast cancer. Unfortunately, breast DCE MRI is primarily recommended in patients at high risk for breast cancer. As a result, relatively few women benefit from breast MRI. Shortening MR breast imaging protocols is a key requirement to reduce cost and improve patient access to this powerful imaging tool for the detection of breast cancer. We developed a new technology for bilateral breast imaging that learns and models temporal behaviors through a local low rank (LLR) constraint that differs from previous approaches in breast MR iterative image reconstruction. We present an imaging methodology that delivers simultaneously higher spatial and temporal resolution than any previously published methods and a robust technology whose performance does not depend on lesion size, morphology or heterogeneity. Furthermore, we adopt an early enhancement phase approach which provides similar or more valuable information than the current methodology with a much shorter scan time. We present an ultra-fast (10 s) volumetric bilateral breast MRI exam with 0.8 mm isotropic resolution, surpassing today's standard clinical resolution while providing temporal resolutions six-to-eighteen-fold faster. By simultaneously providing high spatial and temporal information of the brief but important early enhancement phase, we provide clinicians and researchers with the capability to extract all the diagnostic and lesion characterization data possible from early enhancement phase. The goal for this project was to develop and demonstrate the feasibility of a high-performance sequence for abbreviated breast MRI. Though numerous accelerated methods have previously been proposed, very little validation of the information they derive has been generated due to the complexity of testing reconstruction methods and lesion-dependent imaging performance without a reference standard for comparison. We validated the effectiveness of the method to create high temporal fidelity in a digital phantom and demonstrated the feasibility of our proposed approach with 11 clinical subjects.
Author: Su Jin Kim Hsieh
Publisher: Springer Nature
ISBN: 303084546X
Category : Medical
Languages : en
Pages : 466
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Book Description
The available information on breast cancer has evolved so rapidly that a textbook understanding is no longer sufficient to make sound therapeutic decisions. Further, the latest findings and data are spread throughout the scientific literature of various medical fields, making it difficult for medical professionals to keep abreast of these advances, and to apply them in their day-to-day work. This book provides updated information on breast cancer, such as the modern molecular classification and staging, and demonstrates how imaging with pathologic correlation can be used in management decisions. In addition, it identifies the most suitable imaging modalities for screening, diagnosis and monitoring for each clinical case. Given its scope, the book offers a valuable resource for all medical professionals (practicing or still in training) whose work involves breast cancer, including radiologists, breast surgeons, pathologists, radiotherapists and nuclear medicine professionals.
Author: Hans-Ulrich Kauczor
Publisher: Springer Science & Business Media
ISBN: 354034618X
Category : Medical
Languages : en
Pages : 315
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Book Description
During the past decade significant developments have been achieved in the field of magnetic resonance imaging (MRI), enabling MRI to enter the clinical arena of chest imaging. Standard protocols can now be implemented on up-to-date scanners, allowing MRI to be used as a first-line imaging modality for various lung diseases, including cystic fibrosis, pulmonary hypertension and even lung cancer. The diagnostic benefits stem from the ability of MRI to visualize changes in lung structure while simultaneously imaging different aspects of lung function, such as perfusion, respiratory motion, ventilation and gas exchange. On this basis, novel quantitative surrogates for lung function can be obtained. This book provides a comprehensive overview of how to use MRI for imaging of lung disease. Special emphasis is placed on benign diseases requiring regular monitoring, given that it is patients with these diseases who derive the greatest benefit from the avoidance of ionizing radiation.
Author: E. Edmund Kim
Publisher: Springer Science & Business Media
ISBN: 9780387950280
Category : Medical
Languages : en
Pages : 322
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Book Description
Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.
Author: Michael Fuchsjäger
Publisher: Springer
ISBN: 9783030949204
Category : Medical
Languages : en
Pages : 0
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Book Description
This superbly illustrated book provides a thorough, up-to-date overview of diagnostic breast imaging and therapy. Drs. Elizabeth Morris, Michael Fuchsjäger, and Thomas Helbich, three experts in the field, have collaborated with colleagues from their institutions and selected medical centers to share their expertise. The coverage ranges from basic information on imaging technologies and interventional equipment and how to use them optimally to the application of advanced high-end techniques for screening and assessment in any given professional environment. Readers will find clear instruction on the various breast interventional procedures guided by stereotaxis, ultrasound, and magnetic resonance imaging in wide clinical use. The management of patients with ductal carcinoma in situ and high-risk breast cancer is considered separately. Furthermore, the role of minimally invasive therapy is examined, and advice is provided on post-therapy evaluation, including breast implants. A comprehensive diagnostic atlas with hundreds of images completes this volume and addresses the spectrum of various clinical situations.
Author: Tobias Knopp
Publisher: Springer Science & Business Media
ISBN: 364204199X
Category : Medical
Languages : en
Pages : 211
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Book Description
This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.
Author: Sanjiv Sam Gambhir
Publisher: Cambridge University Press
ISBN: 1139489526
Category : Science
Languages : en
Pages :
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Book Description
Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilise. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered.
Author: S. Saini
Publisher: Springer Science & Business Media
ISBN: 8847004136
Category : Medical
Languages : en
Pages : 213
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Book Description
This book describes current examination techniques and advanced clinical applications of state-of-the-art multidetector computed tomography (MDCT) scanners. There are contributions from several distinguished radiologists and clinicians. Each chapter is written from a practical perspective, so that radiologists, residents, medical physicists, and radiology technologists can obtain relevant information about MDCT applications.
Author: Olaf Minet
Publisher: SPIE-International Society for Optical Engineering
ISBN:
Category : Medical
Languages : en
Pages : 746
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Book Description
SPIE Milestones are collections of seminal papers from the world literature covering important discoveries and developments in optics and photonics.
Author: Pilar Garcia-Peña
Publisher: Springer
ISBN: 3642373372
Category : Medical
Languages : en
Pages : 542
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Book Description
Since the second edition of Pediatric Chest Imaging was published in 2007, there have been further significant advances in our understanding of chest diseases and continued development of new imaging technology and techniques. The third, revised edition of this highly respected reference publication has been thoroughly updated to reflect this progress. Due attention is paid to the increased role of hybrid imaging, and entirely new chapters cover topics such as interventional radiology, lung MRI, functional MRI, diffuse/interstitial lung disease, and cystic fibrosis. As in previous editions, the focus is on technical aspects of modern imaging modalities, their indications in pediatric chest disease, and the diagnostic information that they supply. Pediatric Chest Imaging will be an essential asset for pediatricians, neonatologists, cardiologists, radiologists, and pediatric radiologists everywhere.
