Trends in Eicosanoid Biology

Trends in Eicosanoid Biology PDF Author: Bengt Samuelsson
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 296

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Trends in Eicosanoid Biology

Trends in Eicosanoid Biology PDF Author: Bengt Samuelsson
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 296

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Book Description


Advances in Prostaglandin and Thromboxane Research: Trends in eicosanoid biology

Advances in Prostaglandin and Thromboxane Research: Trends in eicosanoid biology PDF Author: Bengt Samuelsson
Publisher:
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 294

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Prostaglandins, Leukotrienes and Other Eicosanoids

Prostaglandins, Leukotrienes and Other Eicosanoids PDF Author: Friedrich Marks
Publisher: John Wiley & Sons
ISBN: 3527613633
Category : Science
Languages : en
Pages : 408

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Book Description
Polyunsaturated fatty acids are essential for human cell metabolism. As precursors of a very large and extremely versatile family of signaling compounds they play a key role in intracellular communication. Eicosanoids constitute one of the most abundant and prominent subfamilies of these fatty acid derivatives which are formed primarily along oxidative pathways. Prostaglandins, leukotrienes, and related eicosanoids have a modulatory function in mammalian cells and are responsible for tissue responses such as inflammation or wound repair. Increasing activity in eicosanoid research sheds new light on today's most common diseases including atherosclerosis, cancer, Alzheimer's, allergies, and rheumatic diseases. The recent advances already have far-reaching implications in medicine. This detailed account, written by leading experts, covers the ground-breaking developments in recent eicosanoid research. The topics span eicosanoid biogenesis, new aspects of their pathophysiology, for example their influence on the cardiovascular system, as well as the clinical application of synthetic eicosanoids and their antagonists. Researchers and students working in biochemistry or in pharmaceutical, physiological, medicinal and neurochemistry will value this informative introduction to one of the most rapidly developing fields in cell biology.

Advances in Eicosanoid Research

Advances in Eicosanoid Research PDF Author: C.N. Serhan
Publisher: Springer Science & Business Media
ISBN: 3662040476
Category : Science
Languages : en
Pages : 286

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Book Description
Over the last few years, we have witnessed tremendous progress in the field of eicosanoids and their therapeutic applications. Receptor an tagonists for leukotrienes have been tested as anti-inflammatories and are on the market as a treatment for asthma. Receptor agonists for pro stacyclin are being tested for the treatment of peripheral vascular dis ease, and selective inhibitors of cyclooxygenase type II were just ap proved for the treatment of rheumatoid arthritis. All these developments are the culmination of many years and man-hours of careful research. The field has now entered an upswing that will result in novel thera peutic applications within the next 10 years. New molecules and me diators have been identified, new enzymes and pathways elucidated and new therapeutic approaches have emerged. The concept of ei cosanoids as "pro-inflammatory" molecules is being challenged, and their role as regulators is increasingly recognized. In fact, some of these molecules may be important endogenous anti-inflammatory agents.

Prostaglandins and Related Compounds

Prostaglandins and Related Compounds PDF Author: Bengt Samuelsson
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781702386
Category : Medical
Languages : en
Pages : 616

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Eicosanoid Protocols

Eicosanoid Protocols PDF Author: Elias A Lianos
Publisher: Springer Science & Business Media
ISBN: 1592592635
Category : Science
Languages : en
Pages : 298

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Book Description
In Eicosanoid Protocols, Elias A. Lianos and a panel of hands-on experts present cutting-edge methods for the study of eicosanoids, including prostaglandins, thromboxanes, and leukotrienes. The readily reproducible methods described hereconcentrate on studying the regulation of expression and function of enzymes, particularly cyclooxygenase (and its two isoforms), phospholipase A2, and lipoxygenases involved in the synthesis of established eicosanoids. Additional chapters are devoted to the characterization and distribution of the thromboxane A2 receptor in tissues and the biological roles of novel eicosanoids. Timely and authoritative, the methods in this book will help their users in exploring the pathobiology of inflammation. Eicosanoid Protocols offers new and established researchers powerful, state-of-the-art tools to probe the regulation and function of eicosanoids.

Eicosanoids, Lipid Peroxidation and Cancer

Eicosanoids, Lipid Peroxidation and Cancer PDF Author: Santosh K. Nigam
Publisher: Springer Science & Business Media
ISBN: 3642734243
Category : Medical
Languages : en
Pages : 358

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Book Description
This volume offers you up-to-date, expert reviews of this fast-moving field.The main topics are based on the interrelationships between arachidonate metabolism, platelet-activating factor, lipid peroxidation and cancer. The reviews provide vital information for the specialist and will also be of value to a wide audience interested in developments in cell biology, pharmacology, pathology, biochemistry and cancer.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 PDF Author: Kenneth V. Honn
Publisher: Springer
ISBN: 9780306453601
Category : Science
Languages : en
Pages : 555

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Book Description
Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction. One of the most exciting developments explored within this collection of articles is the expression of the novel isoform of cyclooxygenase (cox-2), which may play a large role in the development of anti-inflammatory drugs.

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2

Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Radiation Injury 2 PDF Author: Kenneth V Honn
Publisher:
ISBN: 9781461553267
Category :
Languages : en
Pages : 584

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Leukotrienes as Mediators of Asthma and Inflammation

Leukotrienes as Mediators of Asthma and Inflammation PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 357

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Book Description