Ketamine for Treatment-Resistant Depression

Ketamine for Treatment-Resistant Depression PDF Author: Gustavo H. Vazquez
Publisher: Academic Press
ISBN: 0128210346
Category : Medical
Languages : en
Pages : 170

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Book Description
Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. - Provides efficacy research on ketamine as a treatment for depression - Identifies best practices for clinical use, both long-term and acute - Discusses the molecular mechanisms and neurobiology of action

Ketamine for Treatment-Resistant Depression

Ketamine for Treatment-Resistant Depression PDF Author: Gustavo H. Vazquez
Publisher: Academic Press
ISBN: 0128210346
Category : Medical
Languages : en
Pages : 170

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Book Description
Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. - Provides efficacy research on ketamine as a treatment for depression - Identifies best practices for clinical use, both long-term and acute - Discusses the molecular mechanisms and neurobiology of action

Neurobiology of Depression

Neurobiology of Depression PDF Author: Joao Quevedo
Publisher: Academic Press
ISBN: 9780128133330
Category : Medical
Languages : en
Pages : 352

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Book Description
Depression is one of the most common mental-health disorders, caused by a variety of genetic, biological, environmental, and psychological factors combined. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission; however, only approximately one third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness, and certain symptomatic clusters may be promising targets for novel therapeutics, such as drug and psychological treatments for the management of the cognitive impairments that can encompass several domains and contribute to psychosocial function, and that can persist for many patients even in periods of symptomatic remission. Neurobiology of Depression synthesizes the basic neurobiology of major depressive disorder with discussion of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing researchers' perspectives and may revolutionize research into depression. The basic foundational understanding of the neurobiology underlying the disorder, as well as the comprehensive summary of the most recent advances in research, combine to aid advanced students and researchers in their understanding of MDD and change the landscape of the management of depression with the development of novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to antidepressants to novel therapeutics Synthesizes discussion of cellular and molecular mechanisms underlying symptoms with clinical aspects of depression for a thorough understanding of the disorder

Recent Advances and Challenges in the Treatment of Major Depressive Disorder

Recent Advances and Challenges in the Treatment of Major Depressive Disorder PDF Author: Yong-Ku Kim
Publisher: Springer Nature
ISBN: 9819744024
Category :
Languages : en
Pages : 434

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Book Description


Translational Research Methods for Alcohol Use Disorders

Translational Research Methods for Alcohol Use Disorders PDF Author: Melissa A. Cyders
Publisher: Springer Nature
ISBN: 1071632671
Category : Medical
Languages : en
Pages : 205

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Book Description
This volume covers the latest translational research methods used to study Alcohol Use Disorders (AUD). The chapters in this book highlight cross-species complementary approaches and discusses ways that this translational work will further advance scientific progress in this field. In the Neuromethods series style, chapter include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Research Methods for Alcohol Use Disorders is a valuable resource for all students and researchers interested in expanding their knowledge of AUD.

Translational Research Models and Methods for Mother-Infant Interactions and Developmental Studies

Translational Research Models and Methods for Mother-Infant Interactions and Developmental Studies PDF Author: Josephine Johns
Publisher: Frontiers Media SA
ISBN: 2889190455
Category :
Languages : en
Pages : 360

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Book Description
The disruption of mother-infant interactions can have life-long detrimental consequences for offspring and mothers. This topic of Frontiers will focus on maternal-infant interactions including factors that may affect or alter infant or child development and maternal response capability in clinical and preclinical (animal) populations. Articles may highlight topics such as drug abuse, maternal neglect, altered reward systems, stress, biological and neural system development, child and infant behavioral development, genetics/epigenetics and intergenerational studies. Submissions can include research methods papers, reviews, original research articles, techniques and opinion articles that address the topics of interest. This Research Topic will highlight translational research including common measures and results found in both animal and human studies. Please contact one of the Editors for submission proposals or for additional information.

Translational Neuroimaging

Translational Neuroimaging PDF Author: Robert A. McArthur
Publisher: Academic Press
ISBN: 0123869455
Category : Medical
Languages : en
Pages : 464

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Book Description
This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders.

Depression and Diabetes

Depression and Diabetes PDF Author: Wayne Katon
Publisher: John Wiley & Sons
ISBN: 1119957478
Category : Medical
Languages : en
Pages : 197

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Book Description
In recent years, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. The WPA is providing an update of currently available evidence on these interrelationships by the publication of three books, dealing with the comorbidity of depression with diabetes, heart disease and cancer. Depression is a frequent and serious comorbid condition in diabetes, which adversely affects quality of life and the long-term prognosis. Co-occurrent depression presents peculiar clinical challenges, making both conditions harder to manage. Depression and Diabetes is the first book devoted to the interaction between these common disorders. World leaders in diabetes, depression and public health synthesize current evidence, including some previously unpublished data, in a concise, easy-to-read format. They provide an overview of the epidemiology, pathogenesis, medical costs, management, and public health and cultural implications of the comorbidity between depression and diabetes. The book describes how the negative consequences of depression in diabetes could be avoided, given that effective depression treatments for diabetic patients are available. Its practical approach makes the book ideal for all those involved in the management of these patients: psychiatrists, psychologists, diabetologists, general practitioners, diabetes specialist nurses and mental health nurses.

Personalized Psychiatry

Personalized Psychiatry PDF Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 594

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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Treatment-Resistant Depression

Treatment-Resistant Depression PDF Author:
Publisher: Elsevier
ISBN: 032395779X
Category : Science
Languages : en
Pages : 190

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Book Description
Progress in Brain Research, Volume 278, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters on Treatment Resistant Depression overview in Adult, Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Headache and Treatment Resistant Depression, Insomnia and Treatment Resistant Depression, Tinnitus and Treatment Resistant Depression, Genetics of Antidepressant Response and Treatment Resistant Depression, Neuroinflammation via Gut-Microbiota-Brain Axis in Treatment Resistant Depression, Molecular Imaging findings for Treatment Resistant Depression, and more. Additional sections cover Functional MRI markers for Treatment Resistant Depression: Insights and Current Challenges, Medication Strategies for Treatment Resistant Depression, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Next Generation Antidepressants with Novel Mechanisms for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, and Psychiatric Rehabilitation for Treatment Resistant Depression. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Progress in Brain Research serials - Updated release includes the latest information on Treatment-Resistant Depression

Depression in Parents, Parenting, and Children

Depression in Parents, Parenting, and Children PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309121787
Category : Medical
Languages : en
Pages : 488

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Book Description
Depression is a widespread condition affecting approximately 7.5 million parents in the U.S. each year and may be putting at least 15 million children at risk for adverse health outcomes. Based on evidentiary studies, major depression in either parent can interfere with parenting quality and increase the risk of children developing mental, behavioral and social problems. Depression in Parents, Parenting, and Children highlights disparities in the prevalence, identification, treatment, and prevention of parental depression among different sociodemographic populations. It also outlines strategies for effective intervention and identifies the need for a more interdisciplinary approach that takes biological, psychological, behavioral, interpersonal, and social contexts into consideration. A major challenge to the effective management of parental depression is developing a treatment and prevention strategy that can be introduced within a two-generation framework, conducive for parents and their children. Thus far, both the federal and state response to the problem has been fragmented, poorly funded, and lacking proper oversight. This study examines options for widespread implementation of best practices as well as strategies that can be effective in diverse service settings for diverse populations of children and their families. The delivery of adequate screening and successful detection and treatment of a depressive illness and prevention of its effects on parenting and the health of children is a formidable challenge to modern health care systems. This study offers seven solid recommendations designed to increase awareness about and remove barriers to care for both the depressed adult and prevention of effects in the child. The report will be of particular interest to federal health officers, mental and behavioral health providers in diverse parts of health care delivery systems, health policy staff, state legislators, and the general public.