Emerging Therapeutic Approaches for Cystic Fibrosis

Emerging Therapeutic Approaches for Cystic Fibrosis PDF Author: Miquéias Lopes-Pacheco
Publisher: Frontiers Media SA
ISBN: 2889633675
Category :
Languages : en
Pages : 281

Get Book Here

Book Description

Emerging Therapeutic Approaches for Cystic Fibrosis

Emerging Therapeutic Approaches for Cystic Fibrosis PDF Author: Miquéias Lopes-Pacheco
Publisher: Frontiers Media SA
ISBN: 2889633675
Category :
Languages : en
Pages : 281

Get Book Here

Book Description


Frontiers in Clinical Drug Research – Dementia: Volume 2

Frontiers in Clinical Drug Research – Dementia: Volume 2 PDF Author: José Juan Antonio Ibarra Arias
Publisher: Bentham Science Publishers
ISBN: 9815039482
Category : Science
Languages : en
Pages : 277

Get Book Here

Book Description
Among neurodegenerative diseases, those that lead to a state of dementia are the aim of several investigations. Dementia is a chronic disease the prevalence of which is increasing worldwide. The number of dementia patients in the world is approximately 50 million, and it is estimated that the number of patients will reach 131.5 million by 2050. This increase will be accompanied by a significant increase in medical expenditures and other expenses, especially for elderly patients. Therefore, the maintenance cost of dementia in the future is expected to be quite high. For this reason, several investigations aim, firstly, to describe the key mechanisms involved in the origin of dementia and, secondly, to establish preventive and therapeutic strategies in order to understand and mitigate this debilitating pathology. This volume of Frontiers in Clinical Drug Research - Dementia explores the current comorbidities that cause cognitive impairment and the current management alternatives for clinical cases of dementia. The reviews contributed in these volume will provide readers with a current perspective on the subject. The topics covered in this volume include: - Comorbidities inducing mild cognitive impairment - an evaluation of the risk caused by some pathological conditions - Tau-targeted therapy in Alzheimer's disease - history and current state - Emerging nanotherapeutic strategies in Alzheimer's disease - Implication of dehydroepiandrosterone on dementia related to oxidative stress - Polyphenol compounds as potential therapeutic agents in Alzheimer’s disease The volume is a timely update on dementia treatment for clinical physicians, neurologists, gerontologists, pharmaceutical and medicinal chemistry researchers, and physiologists.

The DNA Replication Machinery as Therapeutic Targets

The DNA Replication Machinery as Therapeutic Targets PDF Author: Andrew F. Gardner
Publisher: Frontiers Media SA
ISBN: 2889459276
Category :
Languages : en
Pages : 144

Get Book Here

Book Description
In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins as well as future outlooks and needs.

Metaphors of Family Systems Theory

Metaphors of Family Systems Theory PDF Author: Paul C. Rosenblatt
Publisher: Guilford Press
ISBN:
Category : Psychology
Languages : en
Pages : 256

Get Book Here

Book Description
If family therapy is like a camera through which clients are able to view their lives, then the treatment method used by clinicians could be considered the lens, offering different ways of seeing. In Metaphors of Family Systems Theory, Paul C. Rosenblatt explores the metaphors of family systems theory that form the conceptual foundation - the lens - of a great deal of therapy, research, theory, education, and policy making in the family field. He demonstrates the value of testing out theoretical or alternative metaphors - other lenses - to provide new perspectives and a fresh means of gaining clarity. The literature that informs family therapy is rich with striking accounts of how therapeutic metaphors have helped to move families into healthier, energizing, freeing, and more satisfying relationships, yet little attention has been devoted to the development of alternative theoretical metaphors. This innovative new work investigates the uses and limitations of the standard metaphors of family systems theory. Perhaps more important, it also provides the means to generate alternative theoretical metaphors to stimulate new thinking about family systems. Rosenblatt asserts that the capacity to recognize metaphors will enable clinicians and clients to identify biases, hidden implications, and reification, as well as what may have been overlooked. He shows the way this ability also helps us to organize and remember information, and to better appreciate the multilayeredness of "reality". Initial chapters define metaphor and discuss family systems theory, as well as the uses and limitations of standard therapeutic metaphors. The chapters examine the notion of the family as an entity, themetaphor of "system", and the major systemic metaphors. Rosenblatt extends his analysis to the idea of family boundary and to the closely related metaphors of family subsystem, family boundary permeability, and family boundary ambiguity. He also analyzes the metaphors of family structure, systems control, family rules, and negative and positive feedback. Later chapters apply these ideas to the metaphors of communication, therapeutic goals, the therapist in the system, and family response to intervention. Rosenblatt Illustrates new insights with a variety of experience-based metaphors and presents strategies for the evaluation and development of new theoretical metaphors for family systems. Unique and innovative, this book offers a fresh perspective for anyone working with metaphors of family systems theory. Of special interest to family therapists, family researchers, social workers, and other mental health professionals working in the family field, it is especially useful as a text for courses in family systems theory, theories of family therapy, and theory construction.

New Frontiers in Offender Treatment

New Frontiers in Offender Treatment PDF Author: Elizabeth L. Jeglic
Publisher: Springer
ISBN: 3030010309
Category : Social Science
Languages : en
Pages : 322

Get Book Here

Book Description
This book reviews how new and promising evidence-based interventions are being used with those involved in the criminal justice system. While there has been an increased emphasis on evidence-based practice within forensic treatment, there remains a disjoint between what we know works and adapting these interventions to those involved in the criminal justice system. This book seeks to bridge that gap by providing an overview of what we know works and how that information has been translated into offender treatment. In addition, it highlights avenues where additional research is needed. This book is comprised of three parts: In the first part, current models of correctional treatment including the Risk, Needs, Responsivity Model, The Good Lives Model and Cognitive Behavioral Models are presented. In the second part, the chapters address clinical issues such as the therapeutic alliance, clinician factors, and diversity related issues that impact treatment outcome. In the third and final part of the book, adaptions of innovative and cutting-edge evidence-based treatments such as Dialectical Behavior Therapy, Trauma Informed Care, Mindfulness, Motivational Interviewing, Assertive Community Treatment, Multisystemic Treatment, New frontiers in Intimate Partner Violence treatment, and the current research on the treatment of those with psychopathy are presented. Research supporting these treatment approaches targeting areas such as self-management, psychological well-being, treatment engagement and retention and their relationship to recidivism will be reviewed, while their adaptation for use with forensic populations is discussed. The book concludes with the editors’ summary of the findings and a discussion of the future of evidence-based interventions within the field of forensic psychology.

Gene Therapy in the CNS – Progress and Prospects for Novel Therapies

Gene Therapy in the CNS – Progress and Prospects for Novel Therapies PDF Author: Casper René Gøtzsche
Publisher: Frontiers Media SA
ISBN: 2889718522
Category : Science
Languages : en
Pages : 188

Get Book Here

Book Description


STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets

STATs and IRFs in Innate Immunity: From Transcriptional Regulators to Therapeutic Targets PDF Author: Chien-Kuo Lee
Publisher: Frontiers Media SA
ISBN: 2889631257
Category :
Languages : en
Pages : 221

Get Book Here

Book Description


The State of the Art in Creative Arts Therapies

The State of the Art in Creative Arts Therapies PDF Author: Tal Shafir
Publisher: Frontiers Media SA
ISBN: 2889635619
Category :
Languages : en
Pages : 451

Get Book Here

Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 8

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 8 PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681089327
Category : Science
Languages : en
Pages : 322

Get Book Here

Book Description
Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The eighth volume of the book features reviews on these topics: - Key data management elements in clinical trials for oncological therapeutics - Prospects for therapeutic targeting of microRNAs in brain tumors - Breast cancer vaccines: current status and future approach - Desmocollin-3 and cancer - MDM2-p53 antagonists under clinical evaluation: a promising cancer targeted therapy for cancer patients harbouring wild-type tp53 - Towards targeted therapy: anticancer agents targeting cell organelle mitochondria - Anticancer therapeutic strategies in gliomas: chemotherapy, immunotherapy, and molecularly targeted therapy in adults.

Person-Centred Therapy Today

Person-Centred Therapy Today PDF Author: Dave Mearns
Publisher: SAGE
ISBN: 9780761965619
Category : Psychology
Languages : en
Pages : 260

Get Book Here

Book Description
`At the risk of being directive, I would say you should buy this book. It contains some of the most stimulating and refreshing ideas to have emerged in the person-centred literature since On Becoming a Person '- Person Centred Practice Person-Centred Therapy Today makes a timely and significant contribution to the development of one of the most popular and widely-used therapeutic approaches. `This is a book that is rooted in the origins of person-centred therapy but stands at the cutting edge of new ideas developing in this tradition. It will reinvigorate those of us already immersed in this tradition. It should convince newcomers of the vitality and potential of this approach to thera