Theoretical and Mathematical Foundations of Human Health Risk Analysis PDF Download
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Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461561434
Category : Technology & Engineering
Languages : en
Pages : 228
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Book Description
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.
Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461561434
Category : Technology & Engineering
Languages : en
Pages : 228
Get Book Here
Book Description
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.
Author: Douglas J. Crawford-Brown
Publisher: Springer
ISBN: 9781461378150
Category : Technology & Engineering
Languages : en
Pages : 208
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Book Description
Scientists and regulators have struggled to define the role of theory, experiments, models and common sense in risk analysis. This situation has been made worse by the isolation of theory from modeling, of experimentation from theory, and of practical action from basic science. This book arises from efforts at regulatory agencies and industries to bring more science into health risk analysis so that society may better use limited resources to improve public health. This book covers: the characterization of exposure to pollutants and other sources of risk; the movement of pollutants into the body via inhalation; ingestion, dermal absorption, and exposures to radiation; the movement of a pollutant as it cascades through the tissues and organs of the body; and the development of principles and models for dose-response modeling. The book shows how an understanding of the biological, chemical, and physical properties of the environment and of the human body can guide the selection of mathematical models, and how these models can aid in estimating risks. Included in the book are models covering the full range of topics in human health risk analysis: exposure assessment, rates of intake, deposition and uptake by organs, absorption across membranes, biokinetics, dosimetry, and dose-response. The reader will gain from the book a better understanding of how environmental health science, as applied in risk analysis, can be used to create a more rational basis for the improvement of public health.
Author:
Publisher: DIANE Publishing
ISBN: 1428902295
Category :
Languages : en
Pages : 209
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Book Description
Author: P.J. Bert Hakkinen
Publisher: Elsevier
ISBN: 008053466X
Category : Medical
Languages : en
Pages : 953
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Book Description
Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added.This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. - Serves as an all-in-one resource for toxicology information - New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports - Updated to include the latest internet and electronic sources, e-mail addresses, etc. - Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects
Author: Eric G. Reichard
Publisher:
ISBN: 9781901502114
Category : Drinking water
Languages : en
Pages : 196
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Book Description
Author: Christian N. Madu
Publisher: Springer Nature
ISBN: 3030758346
Category : Business & Economics
Languages : en
Pages : 264
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Book Description
Manufacturers, under pressure from their major stakeholders, integrate environmental issues in the design and management of their products. These stakeholders include customers, regulators, employees, communities, and interest groups who have a common stake in protecting the earth from pollution and in limiting the exploitation of earth's limited natural resources. Manufacturers recognize that being environmentally responsible also offers competitive advantage to the firm. The Handbook of Environmentally Conscious Manufacturing is written as a state-of-the-art reference to guide environmentally conscious manufacturing (ECM). All the contributors have done extensive research and/or practice work in the field of ECM. The Handbook covers all the major topics in Environmentally Conscious Manufacturing. There are specific chapters to deal with sustainable manufacturing, recycling, eco-labelling, life cycle assessment, and ISO 14000 series of standards, as well as decision-making aspects of Environmentally Conscious Manufacturing. Decision-oriented topics on supply chain, decision models, quality initiative, environmental costing and decision support systems are also covered. The influence of ECM on marketing imperative is also covered.
Author: David A. Dornfeld
Publisher: Springer Science & Business Media
ISBN: 1441960163
Category : Technology & Engineering
Languages : en
Pages : 291
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Book Description
Green Manufacturing: Fundamentals and Applications introduces the basic definitions and issues surrounding green manufacturing at the process,machine and system (including supply chain) levels. It also shows, by way of several examples from different industry sectors, the potential for substantial improvement and the paths to achieve the improvement. Additionally, this book discusses regulatory and government motivations for green manufacturing and outlines the path for making manufacturing more green as well as making production more sustainable. This book also: Discusses new engineering approaches for manufacturing and provides a path from traditional manufacturing to green manufacturing Addresses regulatory and economic issues surrounding green manufacturing Details new supply chains that need to be in place before going green Includes state-of-the-art case studies in the areas of automotive, semiconductor and medical areas as well as in the supply chain and packaging areas
Author: Douglas J. Crawford-Brown
Publisher: Springer Science & Business Media
ISBN: 1461552273
Category : Technology & Engineering
Languages : en
Pages : 228
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Book Description
Risk-Based Environmental Decision: Methods and Culture presents the principles of human health risk analysis as they are applied in environmental decisions. It balances the discussion of scientific theory and methods, philosophical analysis, and applications in regulatory decisions. The material is directed towards risk analysts who must apply their skills in a policy setting, and towards policy analysts who must use risk estimates. The presentation is suited ideally as an introductory text on the methods of risk analysis and on the cultural issues that underlie these methodologies. An important feature of Risk-Based Environmental Decision: Methods and Culture is that it is designed around a series of detailed case studies of environmental risk analysis which walk the reader from the historical nature of the problem, to the formulation as a risk-based problem, to the conduct of risk analysis, and on to the application, debate, and defense of the risk analysis.
Author: Robert S. Raucher
Publisher: American Water Works Association
ISBN: 1583211926
Category : Cost effectiveness
Languages : en
Pages : 386
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Book Description
To assist the implementation of benefit-cost analysis, this research report describes issues and techniques related to estimating the human health risk reduction benefits provided by actions that reduce contaminant concentrations in drinking water, and discusses how these benefits should be compared to costs. Material is relevant for evaluating the benefits and costs of federal and state regulatory actions such as setting a Maximum Contaminant Level, instituting treatment requirements, and implementing a guideline or advisory. The report will be of interest to water utility professionals, benefit- cost practitioners, and public policy decision makers. No subject index. Annotation copyrighted by Book News Inc., Portland, OR.
Author: George Christakos
Publisher: Springer Science & Business Media
ISBN: 1475728115
Category : Medical
Languages : en
Pages : 411
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Book Description
Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus provides a holistic, conceptual and quantitative framework for Environmental Health Modelling in space-time. The holistic framework integrates two aspects of Environmental Health Science that have been previously treated separately: the environmental aspect, which involves the natural processes that bring about human exposure to harmful substances; and the health aspect, which focuses on the interactions of these substances with the human body. Some of the fundamental issues addressed in this work include variability, scale, uncertainty, and space-time connectivity. These topics are important in the characterization of natural systems and health processes. Spatiotemporal Environmental Health Modelling: A Tractatus Stochasticus explains why modern stochastics is the appropriate mechanical vehicle for addressing such issues in a rigorous way. In particular, modern stochastics incorporates concepts and methods from probability, classical statistics, geostatistics, statistical mechanics and field theory. The authors present a synthetic view of environmental health that embraces all of the various components and focuses on their mutual interactions. Spatiotemporal Environmental Health Modeling: A Tractatus Stochasticus includes new material on Bayesian maximum entropy estimation techniques and space-time random field estimation methods. The authors show why these methods have clear advantages over the classical geostatistical estimation procedures and how they can be used to provide accurate space-time maps of environmental health processes. Also included are expositions of diagrammatic perturbation and renormalization group analysis, which have not been previously discussed within the context of Environmental Health. Finally, the authors present stochastic indicators that can be used for large-scale characterization of contamination and investigations of health effects at the microscopic level. This book will be a useful reference to both researchers and practitioners of Environmental Health Sciences. It will appeal specifically to environmental engineers, geographers, geostatisticians, earth scientists, toxicologists, epidemiologists, pharmacologists, applied mathematicians, physicists and biologists.
