Framework for the use of systematic review in chemical risk assessment PDF Download
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Author:
Publisher: World Health Organization
ISBN: 924003448X
Category : Medical
Languages : en
Pages : 77
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Book Description
Author: National Academies Of Sciences Engineeri
Publisher: National Academies Press
ISBN: 9780309683869
Category : Nature
Languages : en
Pages :
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Book Description
Systematic review - a scientific investigation that focuses on a specific question and uses explicit, prespecified scientific methods to identify, select, assess, and summarize the findings of similar but separate studies - has become the foundation for assessing evidence to be used for decision making in a variety of health contexts, including health care and public health. At the request of the Environmental Protection Agency (EPA), this publication reviews EPA's 2018 guidance document Application of Systematic Review in TSCA (Toxic Substances and Control Act) Risk Evaluations and associated materials to determine whether the process is comprehensive, workable, objective, and transparent.
Author:
Publisher: World Health Organization
ISBN: 924003448X
Category : Medical
Languages : en
Pages : 77
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 030904894X
Category : Science
Languages : en
Pages : 668
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Book Description
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
Author: Dennis J. Paustenbach
Publisher: John Wiley & Sons
ISBN: 111974296X
Category : Technology & Engineering
Languages : en
Pages : 1319
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Book Description
Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.
Author: United States. General Accounting Office
Publisher:
ISBN:
Category : Chemicals
Languages : en
Pages : 72
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Book Description
Author: DIANE Publishing Company
Publisher: DIANE Publishing
ISBN: 9780788115141
Category : Medical
Languages : en
Pages : 70
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Book Description
Author: Kelly A. Tzoumis
Publisher: Bloomsbury Publishing USA
ISBN:
Category : Medical
Languages : en
Pages : 747
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Book Description
This one-stop resource is ideal for understanding the extent to which toxic chemicals are used in U.S. industry and agriculture—impacting public health and the environment through everything from industrial solvents to children's toys. Every year, about 4 billion pounds of toxic chemicals are generated and released by U.S. industries. Do these chemicals pose a potential health threat to American families, including vulnerable groups like children and the elderly? Is their manufacture and use adequately regulated to protect both human and environmental health? Is the Chemical Safety for the 21st Century Act, signed in June 2016 by President Barack Obama with bipartisan support, truly the first major overhaul of toxic chemical regulation in 40 years to put human health first, as its supporters asserted? Or is it a fatally flawed bill that does the bidding of industry by undermining strong state environmental and public health laws, as some detractors claim? This two-volume set addresses all of those questions. Moreover, it presents and examines arguments marshaled by business interests, community leaders, scientists, activists, and lawmakers alike. It thus provides users with the information they need to accurately assess the impacts—pro and con—that industrial chemicals are having in shaping the world in which we work, eat, drink, breathe, and play.
Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1000875776
Category : Medical
Languages : en
Pages : 2143
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Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.
Author: C.J. van Leeuwen
Publisher: Springer Science & Business Media
ISBN: 1402061013
Category : Science
Languages : en
Pages : 706
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Book Description
At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. The coverage describes the basic principles and methods of risk assessment within their legislative frameworks (EU, USA, Japan and Canada).
Author: United States. Congress. Senate. Committee on Environment and Public Works. Subcommittee on Toxic Substances and Environmental Oversight
Publisher:
ISBN:
Category : Chemicals
Languages : en
Pages : 148
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Book Description
