The Role of Mechanics in the Study of Lipid Bilayers

The Role of Mechanics in the Study of Lipid Bilayers PDF Author: David J. Steigmann
Publisher: Springer
ISBN: 3319563483
Category : Science
Languages : en
Pages : 338

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Book Description
This book is the first collection of lipid-membrane research conducted by leading mechanicians and experts in continuum mechanics. It brings the overall intellectual framework afforded by modern continuum mechanics to bear on a host of challenging problems in lipid membrane physics. These include unique and authoritative treatments of differential geometry, shape elasticity, surface flow and diffusion, interleaf membrane friction, phase transitions, electroelasticity and flexoelectricity, and computational modelling.

The Role of Mechanics in the Study of Lipid Bilayers

The Role of Mechanics in the Study of Lipid Bilayers PDF Author: David J. Steigmann
Publisher: Springer
ISBN: 3319563483
Category : Science
Languages : en
Pages : 338

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Book Description
This book is the first collection of lipid-membrane research conducted by leading mechanicians and experts in continuum mechanics. It brings the overall intellectual framework afforded by modern continuum mechanics to bear on a host of challenging problems in lipid membrane physics. These include unique and authoritative treatments of differential geometry, shape elasticity, surface flow and diffusion, interleaf membrane friction, phase transitions, electroelasticity and flexoelectricity, and computational modelling.

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Lipid Bilayers

Lipid Bilayers PDF Author: J. Katsaras
Publisher: Springer Science & Business Media
ISBN: 366204496X
Category : Science
Languages : en
Pages : 304

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Book Description
Provides the reader with an up to date insight of the current state of the art in the field of lipid bilayer research and the important insights derived for the understanding of the complex and varied behaviour of biological membranes and its function.

Statistical Mechanics of Lipid Bilayers

Statistical Mechanics of Lipid Bilayers PDF Author: Mark Menniti Stecker
Publisher:
ISBN:
Category :
Languages : en
Pages : 574

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Book Description


Permeability and Stability of Lipid Bilayers

Permeability and Stability of Lipid Bilayers PDF Author: E. Anibal Disalvo
Publisher: CRC Press
ISBN: 1351425382
Category : Science
Languages : en
Pages : 298

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Book Description
This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

An Experimental and Computational Multiscale Study of Model Cellular Lipid Bilayer Membranes

An Experimental and Computational Multiscale Study of Model Cellular Lipid Bilayer Membranes PDF Author: Matthew Ian Hoopes
Publisher:
ISBN: 9781124665825
Category :
Languages : en
Pages :

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Book Description
Lipid molecules self-assemble into fluid membranes only two molecules thick to form a dual leaflet structure with fascinating properties. These dynamic assemblies not only provide for compartmentalization and transportation in the three dimensional world of biological cells, but also play a part in the organization of a two dimensional community of molecules in the membrane itself. This system of lipids, proteins, sugars, and other biological molecules are governed by the laws of soft matter physics. Understanding the relationships between geometry, energy, and time scale in these biological systems is necessary for insight into how dynamic processes, such as sorting, signaling, and transport function in the cell. Results from computational and experimental studies of membranes are presented with emphasis on the mechanics and thermodynamics of the membrane across multiple scales. Atomistic studies of skin lipids in the stratum corneum layer are presented along with system perturbations resulting from small amounts of an additive. A coarse-grained lipid model illustrates the effects of membrane adsorption in supported lipid bilayers including changes to area per lipid, density, and pressure profiles. Finally, macroscopic experimental systems of multilamellar supported lipid bilayers are used to demonstrate the interactions between phase separated domains of lipids, membrane bending mechanics, and domain line tension.

Advances in Planar Lipid Bilayers and Liposomes

Advances in Planar Lipid Bilayers and Liposomes PDF Author:
Publisher: Academic Press
ISBN: 0128022019
Category : Science
Languages : en
Pages : 206

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Book Description
The Elsevier book-series "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes. Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers. The APLBL book series gives a survey on recent theoretical as well as experimental results on lipid micro and nanostructures. In addition, the potential use of the basic knowledge in applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products is presented. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

Phase Transitions and Statistical Mechanics of Lipid Bilayers Systems

Phase Transitions and Statistical Mechanics of Lipid Bilayers Systems PDF Author: John Day
Publisher:
ISBN:
Category : Lipids
Languages : en
Pages : 376

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Book Description


Computer Simulation of Biomolecular Systems

Computer Simulation of Biomolecular Systems PDF Author: W.F. van Gunsteren
Publisher: Springer Science & Business Media
ISBN: 9789072199256
Category : Science
Languages : en
Pages : 664

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Book Description
This book is the third volume in this highly successful series. Since the first volume in 1989 and the second in 1993, many exciting developments have occurred in the development of simulation techniques and their application to key biological problems such as protein folding, protein structure prediction and structure-based design, and in how, by combining experimental and theoretical approaches, very large biological systems can be studied at the molecular level. This series attempts to capture that progress. Volume 3 includes contributions that highlight developments in methodology which enable longer and more realistic simulations (e.g. multiple time steps and variable reduction techniques), a study of force fields for proteins and new force field development, a novel approach to the description of molecular shape and the use of molecular shape descriptors, the study of condensed phase chemical reactions, the use of electrostatic techniques in the study of protonation, equilibria and flexible docking studies, structure refinement using experimental data (X-ray, NMR, neutron, infrared) and theoretical methods (solvation models, normal mode analysis, MD simulations, MC lattice dynamics, and knowledge-based potentials). There are several chapters that show progress in the development of methodologies for the study of folding processes, binding affinities, and the prediction of ligand-protein complexes. The chapters, contributed by experienced researchers, many of whom are leaders in their field of study, are organised to cover developments in: simulation methodology the treatment of electrostatics protein structure refinement the combined experimental and theoretical approaches to the study of very large biological systems applications and methodology involved in the study of protein folding applications and methodology associated with structure-based design.

Liposomes, Lipid Bilayers and Model Membranes

Liposomes, Lipid Bilayers and Model Membranes PDF Author: Georg Pabst
Publisher: CRC Press
ISBN: 146650711X
Category : Medical
Languages : en
Pages : 470

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Book Description
As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evo