The Robustness of the Propensity Score in the Presence of Effect Modification

The Robustness of the Propensity Score in the Presence of Effect Modification PDF Author: Mary Ann O'Riordan
Publisher:
ISBN:
Category :
Languages : en
Pages : 128

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The Robustness of the Propensity Score in the Presence of Effect Modification

The Robustness of the Propensity Score in the Presence of Effect Modification PDF Author: Mary Ann O'Riordan
Publisher:
ISBN:
Category :
Languages : en
Pages : 128

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Book Description


Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide PDF Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
ISBN: 1587634236
Category : Medical
Languages : en
Pages : 236

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Book Description
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

Propensity Score Analysis

Propensity Score Analysis PDF Author: Shenyang Guo
Publisher: SAGE
ISBN: 1452235007
Category : Business & Economics
Languages : en
Pages : 449

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Book Description
Provides readers with a systematic review of the origins, history, and statistical foundations of Propensity Score Analysis (PSA) and illustrates how it can be used for solving evaluation and causal-inference problems.

Secondary Analysis of Electronic Health Records

Secondary Analysis of Electronic Health Records PDF Author: MIT Critical Data
Publisher: Springer
ISBN: 3319437429
Category : Medical
Languages : en
Pages : 435

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Book Description
This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a “data desert” when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients.

Analysis of Observational Health Care Data Using SAS

Analysis of Observational Health Care Data Using SAS PDF Author: Douglas E. Faries
Publisher: SAS Press
ISBN: 9781607642275
Category : Medical care
Languages : en
Pages : 0

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Book Description
This book guides researchers in performing and presenting high-quality analyses of all kinds of non-randomized studies, including analyses of observational studies, claims database analyses, assessment of registry data, survey data, pharmaco-economic data, and many more applications. The text is sufficiently detailed to provide not only general guidance, but to help the researcher through all of the standard issues that arise in such analyses. Just enough theory is included to allow the reader to understand the pros and cons of alternative approaches and when to use each method. The numerous contributors to this book illustrate, via real-world numerical examples and SAS code, appropriate implementations of alternative methods. The end result is that researchers will learn how to present high-quality and transparent analyses that will lead to fair and objective decisions from observational data. This book is part of the SAS Press program.

Robustness Tests for Quantitative Research

Robustness Tests for Quantitative Research PDF Author: Eric Neumayer
Publisher: Cambridge University Press
ISBN: 1108415393
Category : Business & Economics
Languages : en
Pages : 269

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Book Description
This highly accessible book presents robustness testing as the methodology for conducting quantitative analyses in the presence of model uncertainty.

Practical Propensity Score Methods Using R

Practical Propensity Score Methods Using R PDF Author: Walter Leite
Publisher: SAGE Publications
ISBN: 1483313395
Category : Social Science
Languages : en
Pages : 225

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Book Description
Practical Propensity Score Methods Using R by Walter Leite is a practical book that uses a step-by-step analysis of realistic examples to help students understand the theory and code for implementing propensity score analysis with the R statistical language. With a comparison of both well-established and cutting-edge propensity score methods, the text highlights where solid guidelines exist to support best practices and where there is scarcity of research. Readers will find that this scaffolded approach to R and the book’s free online resources help them apply the text’s concepts to the analysis of their own data.

Matched Sampling for Causal Effects

Matched Sampling for Causal Effects PDF Author: Donald B. Rubin
Publisher: Cambridge University Press
ISBN: 1139458507
Category : Mathematics
Languages : en
Pages : 5

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Book Description
Matched sampling is often used to help assess the causal effect of some exposure or intervention, typically when randomized experiments are not available or cannot be conducted. This book presents a selection of Donald B. Rubin's research articles on matched sampling, from the early 1970s, when the author was one of the major researchers involved in establishing the field, to recent contributions to this now extremely active area. The articles include fundamental theoretical studies that have become classics, important extensions, and real applications that range from breast cancer treatments to tobacco litigation to studies of criminal tendencies. They are organized into seven parts, each with an introduction by the author that provides historical and personal context and discusses the relevance of the work today. A concluding essay offers advice to investigators designing observational studies. The book provides an accessible introduction to the study of matched sampling and will be an indispensable reference for students and researchers.

Commercial Motor Vehicle Driver Fatigue, Long-Term Health, and Highway Safety

Commercial Motor Vehicle Driver Fatigue, Long-Term Health, and Highway Safety PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309392527
Category : Transportation
Languages : en
Pages : 273

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Book Description
There are approximately 4,000 fatalities in crashes involving trucks and buses in the United States each year. Though estimates are wide-ranging, possibly 10 to 20 percent of these crashes might have involved fatigued drivers. The stresses associated with their particular jobs (irregular schedules, etc.) and the lifestyle that many truck and bus drivers lead, puts them at substantial risk for insufficient sleep and for developing short- and long-term health problems. Commercial Motor Vehicle Driver Fatigue, Long-Term Health and Highway Safety assesses the state of knowledge about the relationship of such factors as hours of driving, hours on duty, and periods of rest to the fatigue experienced by truck and bus drivers while driving and the implications for the safe operation of their vehicles. This report evaluates the relationship of these factors to drivers' health over the longer term, and identifies improvements in data and research methods that can lead to better understanding in both areas.

Bootstrapping

Bootstrapping PDF Author: Christopher Z. Mooney
Publisher: SAGE
ISBN: 9780803953819
Category : Philosophy
Languages : en
Pages : 84

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Book Description
"This book is. . . clear and well-written. . . anyone with any interest in the basis of quantitative analysis simply must read this book. . . . well-written, with a wealth of explanation. . ." --Dougal Hutchison in Educational Research Using real data examples, this volume shows how to apply bootstrapping when the underlying sampling distribution of a statistic cannot be assumed normal, as well as when the sampling distribution has no analytic solution. In addition, it discusses the advantages and limitations of four bootstrap confidence interval methods--normal approximation, percentile, bias-corrected percentile, and percentile-t. The book concludes with a convenient summary of how to apply this computer-intensive methodology using various available software packages.