The Retina and Circadian Rhythms

The Retina and Circadian Rhythms PDF Author: Gianluca Tosini
Publisher: Springer Science & Business Media
ISBN: 1461496136
Category : Medical
Languages : en
Pages : 245

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Book Description
Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.

The Retina and Circadian Rhythms

The Retina and Circadian Rhythms PDF Author: Gianluca Tosini
Publisher: Springer Science & Business Media
ISBN: 1461496136
Category : Medical
Languages : en
Pages : 245

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Book Description
Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.

Extraretinal Photoreception

Extraretinal Photoreception PDF Author: Michael Menaker
Publisher: Elsevier
ISBN: 1483138917
Category : Social Science
Languages : en
Pages : 97

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Book Description
Extraretinal Photoreception

Circadian and Visual Neuroscience

Circadian and Visual Neuroscience PDF Author:
Publisher: Elsevier
ISBN: 0323859445
Category : Science
Languages : en
Pages : 380

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Book Description
Circadian and Visual Neuroscience, Volume 273 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics including Optical set-ups, Psychophysics of Luminance and Color Vision, Psychophysics of non-visual photoreception PRC/IRC/DRC/Spectral Sensitivity, Circadian and visual photometry, Modelling (retina), Modelling (circadian), Techniques for examining vision at the cellular level, Advanced techniques for characterizing the world hyperspectrally, Circadian physiology in mice: Melanopsin, Circadian physiology in mice: Color and cones, Translational aspects of animal studies, Retinal clocks, Primate non-visual physiology, Light and mood in animal models, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research series Updated release includes the latest information on Circadian and Visual Neuroscience

Dopamine Rhythms in the Mammalian Retina

Dopamine Rhythms in the Mammalian Retina PDF Author: Susan Elizabeth Doyle
Publisher:
ISBN:
Category :
Languages : en
Pages : 216

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Book Description


Chronobiology

Chronobiology PDF Author: Pavol Svorc
Publisher: BoD – Books on Demand
ISBN: 1789849004
Category : Medical
Languages : en
Pages : 109

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Book Description
The regular alternation of light and dark affects not only human biological systems, but also the social organization of behavior. The effect of such light modes is manifested in periodic changes in physiological functions and biological rhythms exhibited at every level of life. The book discusses some of the specificities of the circadian rhythms in living organisms and mentions aspects of the control of circadian rhythms as well as experimental and clinical cases that are closely related to circadian disruption. This book can evoke interest in many researchers who want to use this information for the advancement of their research towards a better understanding of the biological time structure.

Circadian Rhythms and Metabolism

Circadian Rhythms and Metabolism PDF Author: Etienne Challet
Publisher: Frontiers Media SA
ISBN: 2889452824
Category : Electronic book
Languages : en
Pages : 190

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Book Description
One of the major breakthroughs of the last decade in the understanding of energy homeostasis is the identification of a reciprocal control between circadian rhythmicity and cellular metabolism. Circadian rhythmicity is a fundamental endogenous process of almost every organism living on Earth. For instance, the alternation of hunger and satiety is not continuous over 24 h, but is instead structured in time along the light/dark cycle. In mammals, the temporal organization of metabolism, physiology and behavior around 24 h is controlled by a network of multiple cellular clocks, synchronized via neuronal and hormonal signals by a master clock located in the suprachiasmatic nuclei of the hypothalamus. This central circadian conductor in the brain is mainly reset by ambient light perceived by the retina, while secondary circadian clocks in other brain areas and peripheral organs can be reset by meal timing. Chronic disruption of circadian rhythms, as seen in human shift-workers (up to 20% of the active population), has been associated with the development of a number of adverse mental and metabolic conditions. Understanding of the functional links between circadian desynchronization and overall health in animal models and humans, however, is still scarce. Interactions between circadian clocks and metabolism can occur at different levels: the molecular clockwork, internal synchronization via neuro-hormonal signals, or external synchronization via photic or feeding cues. This Research Topic comprises a number of reviews as well as research and methods articles that feature recent advancements in the mechanisms linking circadian clocks with energy metabolism, and the pathophysiological implications of these interactions for metabolic health.

The Circadian Clock

The Circadian Clock PDF Author: Urs Albrecht
Publisher: Springer Science & Business Media
ISBN: 1441912622
Category : Science
Languages : en
Pages : 306

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Book Description
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.

Neuronal Input Pathways to the Brain's Biological Clock and their Functional Significance

Neuronal Input Pathways to the Brain's Biological Clock and their Functional Significance PDF Author: Jens Hannibal
Publisher: Springer Science & Business Media
ISBN: 3540277897
Category : Medical
Languages : en
Pages : 84

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Book Description
Rhythmic changes in physiology and behaviour within a 24 h period occur in living organisms on earth to meet the challenges associated with the daily changes in the external environment. The circadian pacemaker responsible for the temporal internal organisation and the generation of endogenous rhythms of approximately 24 h is located in the hypothalamic suprachiasmatic nucleus (SCN) in mammals. The endogenous period generated by the pacemaker is close to, but generally not equal to 24 h and the biological clock therefore needs to be daily adjusted (entrained) by external cues. The daily alteration of light and darkness due to the rotation of our planet on its own axis in relation to the sun is the most prominent "zeitgeber" which adjusts the phase of the circadian rhythms to the astronomical day length, a process known as photoentrainment. In mammals, light is perceived only through photoreceptors located in the retina. Light information is mediated to the SCN via the retinohypothalamic tract (RHT) by activation of the classical photoreceptor system of rods and cones and a more recently identified system of intrinsic photosensitive retinal ganglion cells (ipRGCs) using melanopsin as a photopigment.

Disorders of Circadian Rhythms

Disorders of Circadian Rhythms PDF Author: Arturo Ortega
Publisher: Frontiers Media SA
ISBN: 2889661318
Category : Science
Languages : en
Pages : 105

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Phenomenon of Light

Phenomenon of Light PDF Author: Girish Bhardwaj
Publisher: Notion Press
ISBN: 1685234682
Category : Science
Languages : en
Pages : 130

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Book Description
We all must be aware of the physiology of human beings and plants with respect to the impacts of artificial and natural light. As we are spending maximum of our times staying in indoors, thus it is an essential way of approach, to succeed in our mission of wellbeing and healthy living through the time cue- LIGHT. “GIVE WAY TO THE NATURAL LIGHT”: Deciding on a lighting scheme does not mean deciding only for artificial lighting. Natural lighting is a boon. Even if it is required, make changes according to how the natural sunlight lights up your room. There are several other techniques to aim the incident rays of natural light to a different plane by reflecting those rays. This phrase “close to the sunlight” can be used as a comparisons for the visual acuity along with some parameters like heat, infrared, ultraviolet waves, and intensity of the spectral power distribution. The question is how, what and why? “LIGHT IS THE GOVERNOR OF THE UNIVERSE, AND OUR BODY IS A TYPE OF LITTLE UNIVERSE BY ITSELF.”