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Author: Doogab Yi
Publisher: University of Chicago Press
ISBN: 022614383X
Category : Education
Languages : en
Pages : 331
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Book Description
This title examines the history of biotechnology when it was new, especially when synonymous with recombinant DNA technology. It focuses on the academic community in the San Francisco Bay Area where recombinant DNA technology was developed and adopted as the first major commercial technology for genetic engineering at Stanford in the 1970s. The book argues that biotechnology was initially a hybrid creation of academic and commercial institutions held together by the assumption of a positive relationship between private ownership and the public interest.
Author: Doogab Yi
Publisher: University of Chicago Press
ISBN: 022614383X
Category : Education
Languages : en
Pages : 331
Get Book
Book Description
This title examines the history of biotechnology when it was new, especially when synonymous with recombinant DNA technology. It focuses on the academic community in the San Francisco Bay Area where recombinant DNA technology was developed and adopted as the first major commercial technology for genetic engineering at Stanford in the 1970s. The book argues that biotechnology was initially a hybrid creation of academic and commercial institutions held together by the assumption of a positive relationship between private ownership and the public interest.
Author: Doogab Yi
Publisher: University of Chicago Press
ISBN: 022621611X
Category : Science
Languages : en
Pages : 331
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Book Description
The advent of recombinant DNA technology in the 1970s was a key moment in the history of both biotechnology and the commercialization of academic research. Doogab Yi’s The Recombinant University draws us deeply into the academic community in the San Francisco Bay Area, where the technology was developed and adopted as the first major commercial technology for genetic engineering. In doing so, it reveals how research patronage, market forces, and legal developments from the late 1960s through the early 1980s influenced the evolution of the technology and reshaped the moral and scientific life of biomedical researchers. Bay Area scientists, university administrators, and government officials were fascinated by and increasingly engaged in the economic and political opportunities associated with the privatization of academic research. Yi uncovers how the attempts made by Stanford scientists and administrators to demonstrate the relevance of academic research were increasingly mediated by capitalistic conceptions of knowledge, medical innovation, and the public interest. Their interventions resulted in legal shifts and moral realignments that encouraged the privatization of academic research for public benefit. The Recombinant University brings to life the hybrid origin story of biotechnology and the ways the academic culture of science has changed in tandem with the early commercialization of recombinant DNA technology.
Author: James D. Watson
Publisher: Macmillan
ISBN: 9780716722823
Category : Medical
Languages : en
Pages : 644
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Book Description
An overview of recombitant DNA techniques and surveys advances in recombinant molecular genetics, experimental methods and their results.
Author: Keya Chaudhuri
Publisher: The Energy and Resources Institute (TERI)
ISBN: 8179933202
Category : Science
Languages : en
Pages : 300
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Book Description
Recombinant DNA Technology is focussed on the current state of knowledge on the recombinant DNA technology and its applications. The book will provide comprehensive knowledge on the principles and concepts of recombinant DNA technology or genetic engineering, protein expression of cloned genes, PCR amplification of DNA, RFLP, AFLP and DNA fingerprinting and finally the most recent siRNA technology. It can be used by post-graduate students studying and teachers teaching in the area of Molecular Biology, Biotechnology, Genetics, Microbiology, Life Science, Pharmacy, Agriculture and Basic Medical Sciences.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309176689
Category : Medical
Languages : en
Pages : 254
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Book Description
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Author: Bernard R. Glick
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 724
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Book Description
The second edition explains the principles of recombinant DNA technology as well as other important techniques such as DNA sequencing, the polymerase chain reaction, and the production of monclonal antibodies.
Author: Siddra Ijaz
Publisher: Cambridge Scholars Publishing
ISBN: 1527538443
Category : Science
Languages : en
Pages : 156
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Book Description
Genetic engineering is a rapidly growing field in the area of biological sciences. The driving forces behind this are the challenges encountered by health sectors, agriculture, the environment, and industry. As such, accurate and comprehensive knowledge about the philosophy, principles and application of genetic engineering is indispensable for students and researchers to harness maximum opportunities from this field of science. This volume gathers together comprehensive information regarding genetic engineering from recent studies, and presents it in a coherent manner. As such, it will be of interest to undergraduate and postgraduate students and researchers working in the biological sciences.
Author: Helen Kreuzer
Publisher:
ISBN:
Category : Biotechnology
Languages : en
Pages : 349
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Book Description
Author: Errol C Friedberg
Publisher: World Scientific
ISBN: 9814569062
Category : Science
Languages : en
Pages : 444
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Book Description
With a Foreword writer Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work. In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest. The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present. This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience. While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed. Contents:Part I:Growing Up in BrooklynThe Essential Paul BergCollege — and World War IIWestern Reserve UniversityCopenhagenPart II:Washington University, St. LouisDiscovering Transfer RNAStanford University — and Its Refurbished Department of BiochemistryTranscription and Translation: New DirectionsPart III:Making Recombinant DNA — The First Faltering StepsMaking Recombinant DNA — A Major BreakthroughEcoRI Restriction Endonuclease — A Major Breakthrough“Coincidence is the Word We Use When We Can't See the Levers and Pulleys”Yet Another Stanford ContributionPart IV:An Historic Meeting in HawaiiThe Recombinant DNA ControversyA Momentous Gordon Research ConferenceMaking Recombinant Molecules with Frog DNAThe Controversy Heats UpAsilomar IIThe Dissenters: A Different Point of ViewThe AftermathLegislative and Revisionist Challenges to Recombinant DNAAsilomar II — Lessons LearnedPart V:The Nobel Prize in ChemistryCommercializing the TechnologyLife Goes onThe “Retirement” YearsPublic Policy Issues — and Other InterestsPersonal Challenges Readership: Researchers, graduate students, undergraduates in life sciences, medicine and chemistry and interested lay public. Keywords:Recombinant DNA;Paul Berg;Stanford University;Errol Friedberg;DNA;tRNA;Asilomar Meeting Western Reserve University;Stanley Cohen Gene Cloning;Nobel PrizeReviews: “This is a great and very readable story of a renowned biochemist moving outside his comfort zone to provide needed leadership at a time of national turmoil. Friedberg takes us from Berg's beginnings in Brooklyn in an immigrant Yiddish-speaking family to his receipt of the Nobel Prize. He also describes Berg's guidance of a process of public acceptance of a revolutionary scientific advance — Recombinant DNA technology — that appeared to be hazardous because it was so innovative. The book reads easily, with enough technical discussion to be informative without being too demanding. It also includes an insightful investigation of the mystery of who actually deserves credit for making the technology a reality, which will fascinate other scientists and anyone who cares about the history of science and technology.” David Baltimore Nobel Laureate “Friedberg's book is a valuable addition to the literature on the scientific development of recombinant DNA technology, particularly the interactions among the numerous scientists involved who jockeyed for priority. It also details the life and times of one of the most outstanding biochemists this country has ever produced. ” DNA Repair
Author: Sue Carson
Publisher: Elsevier
ISBN: 0080456545
Category : Science
Languages : en
Pages : 172
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Book Description
This manual is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology, or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students gain hands-on experience from start to finish in subcloning a gene into an expression vector, through purification of the recombinant protein.The second edition has been completely re-written, with new laboratory exercises and all new illustrations and text, designed for a typical 15-week semester, rather than a 4-week intensive course. The “project approach to experiments was maintained: students still follow a cloning project through to completion, culminating in the purification of recombinant protein. It takes advantage of the enhanced green fluorescent protein—students can actually visualize positive clones following IPTG induction. *Cover basic concepts and techniques used in molecular biology research labs*Student-tested labs proven successful in a real classroom laboratories*Exercises simulate a cloning project that would be performed in a real research lab*"Project" approach to experiments gives students an overview of the entire process*Prep-list appendix contains necessary recipes and catalog numbers, providing staff with detailed instructions
