Author: Donald S. Fredrickson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 420
Book Description
"Relying on vast archives of hearings records, correspondence, and extensive personal records and diaries, Dr. Fredrickson recalls the numerous personalities from microbiology, molecular biology, and other scientific disciplines, as well as the leaders among Congress, the administration, and government agencies, environmentalists, and many others, who had a role during this challenging period."--BOOK JACKET.
The Recombinant DNA Controversy
Author: Donald S. Fredrickson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 420
Book Description
"Relying on vast archives of hearings records, correspondence, and extensive personal records and diaries, Dr. Fredrickson recalls the numerous personalities from microbiology, molecular biology, and other scientific disciplines, as well as the leaders among Congress, the administration, and government agencies, environmentalists, and many others, who had a role during this challenging period."--BOOK JACKET.
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 420
Book Description
"Relying on vast archives of hearings records, correspondence, and extensive personal records and diaries, Dr. Fredrickson recalls the numerous personalities from microbiology, molecular biology, and other scientific disciplines, as well as the leaders among Congress, the administration, and government agencies, environmentalists, and many others, who had a role during this challenging period."--BOOK JACKET.
Genetic Alchemy
Author: Sheldon Krimsky
Publisher: Mit Press
ISBN: 9780262610384
Category : Philosophy
Languages : en
Pages : 445
Book Description
Genetic Alchemy summarizes and clarifies the background of policy and ethical issues, the debates engendered by uncertain risks to researchers and the population at large, and the roles played by scientists involved in one of the most prominent and controversial new technologies, gene splicing. The author, Assistant Professor of Urban and Environmental Policy at Tufts University, brings to the topic his experience on the Cambridge Review Board as it considered the siting of a recombinant DNA research facility, and on the NIH's Recombinant DNA Advisory Committee.
Publisher: Mit Press
ISBN: 9780262610384
Category : Philosophy
Languages : en
Pages : 445
Book Description
Genetic Alchemy summarizes and clarifies the background of policy and ethical issues, the debates engendered by uncertain risks to researchers and the population at large, and the roles played by scientists involved in one of the most prominent and controversial new technologies, gene splicing. The author, Assistant Professor of Urban and Environmental Policy at Tufts University, brings to the topic his experience on the Cambridge Review Board as it considered the siting of a recombinant DNA research facility, and on the NIH's Recombinant DNA Advisory Committee.
Oversight and Review of Clinical Gene Transfer Protocols
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030929665X
Category : Medical
Languages : en
Pages : 78
Book Description
Gene transfer research is a rapidly advancing field that involves the introduction of a genetic sequence into a human subject for research or diagnostic purposes. Clinical gene transfer trials are subject to regulation by the U.S. Food and Drug Administration (FDA) at the federal level and to oversight by institutional review boards (IRBs) and institutional biosafety committees (IBCs) at the local level before human subjects can be enrolled. In addition, at present all researchers and institutions funded by the National Institutes of Health (NIH) are required by NIH guidelines to submit human gene transfer protocols for advisory review by the NIH Recombinant DNA Advisory Committee (RAC). Some protocols are then selected for individual review and public discussion. Oversight and Review of Clinical Gene Transfer Protocols provides an assessment of the state of existing gene transfer science and the current regulatory and policy context under which research is investigated. This report assesses whether the current oversight of individual gene transfer protocols by the RAC continues to be necessary and offers recommendations concerning the criteria the NIH should employ to determine whether individual protocols should receive public review. The focus of this report is on the standards the RAC and NIH should use in exercising its oversight function. Oversight and Review of Clinical Gene Transfer Protocols will assist not only the RAC, but also research institutions and the general public with respect to utilizing and improving existing oversight processes.
Publisher: National Academies Press
ISBN: 030929665X
Category : Medical
Languages : en
Pages : 78
Book Description
Gene transfer research is a rapidly advancing field that involves the introduction of a genetic sequence into a human subject for research or diagnostic purposes. Clinical gene transfer trials are subject to regulation by the U.S. Food and Drug Administration (FDA) at the federal level and to oversight by institutional review boards (IRBs) and institutional biosafety committees (IBCs) at the local level before human subjects can be enrolled. In addition, at present all researchers and institutions funded by the National Institutes of Health (NIH) are required by NIH guidelines to submit human gene transfer protocols for advisory review by the NIH Recombinant DNA Advisory Committee (RAC). Some protocols are then selected for individual review and public discussion. Oversight and Review of Clinical Gene Transfer Protocols provides an assessment of the state of existing gene transfer science and the current regulatory and policy context under which research is investigated. This report assesses whether the current oversight of individual gene transfer protocols by the RAC continues to be necessary and offers recommendations concerning the criteria the NIH should employ to determine whether individual protocols should receive public review. The focus of this report is on the standards the RAC and NIH should use in exercising its oversight function. Oversight and Review of Clinical Gene Transfer Protocols will assist not only the RAC, but also research institutions and the general public with respect to utilizing and improving existing oversight processes.
Sources of Medical Technology
Author: Committee on Technological Innovation in Medicine
Publisher: National Academies Press
ISBN: 0309587611
Category : Medical
Languages : en
Pages : 255
Book Description
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Publisher: National Academies Press
ISBN: 0309587611
Category : Medical
Languages : en
Pages : 255
Book Description
Evidence suggests that medical innovation is becoming increasingly dependent on interdisciplinary research and on the crossing of institutional boundaries. This volume focuses on the conditions governing the supply of new medical technologies and suggest that the boundaries between disciplines, institutions, and the private and public sectors have been redrawn and reshaped. Individual essays explore the nature, organization, and management of interdisciplinary R&D in medicine; the introduction into clinical practice of the laser, endoscopic innovations, cochlear implantation, cardiovascular imaging technologies, and synthetic insulin; the division of innovating labor in biotechnology; the government- industry-university interface; perspectives on industrial R&D management; and the growing intertwining of the public and proprietary in medical technology.
Molecular Politics
Author: Susan Wright
Publisher: University of Chicago Press
ISBN: 0226910660
Category : Health & Fitness
Languages : en
Pages : 615
Book Description
The promise of genetic engineering in the early 1970s to profoundly reshape the living world activated a variety of social interests in its future promotion and control. With public safety, gene patents, and the future of genetic research at stake, a wide range of interest groups competed for control over this powerful new technology. In this comparative study of the development of regulatory policy for genetic engineering in the United States and the United Kingdom, Susan Wright analyzes government responses to the struggles among corporations, scientists, universities, trade unions, and public interest groups over regulating this new field. Drawing on archival materials, government records, and interviews with industry executives, politicians, scientists, trade unionists, and others on both sides of the Atlantic, Molecular Politics provides a comprehensive account of a crucial set of policy decisions and explores their implications for the political economy of science. By combining methods from political science and the history of science, Wright advances a provocative interpretation of the evolution of genetic engineering policy and makes a major contribution to science and public policy studies.
Publisher: University of Chicago Press
ISBN: 0226910660
Category : Health & Fitness
Languages : en
Pages : 615
Book Description
The promise of genetic engineering in the early 1970s to profoundly reshape the living world activated a variety of social interests in its future promotion and control. With public safety, gene patents, and the future of genetic research at stake, a wide range of interest groups competed for control over this powerful new technology. In this comparative study of the development of regulatory policy for genetic engineering in the United States and the United Kingdom, Susan Wright analyzes government responses to the struggles among corporations, scientists, universities, trade unions, and public interest groups over regulating this new field. Drawing on archival materials, government records, and interviews with industry executives, politicians, scientists, trade unionists, and others on both sides of the Atlantic, Molecular Politics provides a comprehensive account of a crucial set of policy decisions and explores their implications for the political economy of science. By combining methods from political science and the history of science, Wright advances a provocative interpretation of the evolution of genetic engineering policy and makes a major contribution to science and public policy studies.
The Ultimate Experiment
Author: Nicholas Wade
Publisher:
ISBN: 9780802771490
Category : Genetic engineering
Languages : en
Pages : 185
Book Description
Publisher:
ISBN: 9780802771490
Category : Genetic engineering
Languages : en
Pages : 185
Book Description
Human Genome Editing
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452880
Category : Medical
Languages : en
Pages : 329
Book Description
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Publisher: National Academies Press
ISBN: 0309452880
Category : Medical
Languages : en
Pages : 329
Book Description
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Biography Of Paul Berg, A: The Recombinant Dna Controversy Revisited
Author: Errol C Friedberg
Publisher: World Scientific
ISBN: 9814569062
Category : Biography & Autobiography
Languages : en
Pages : 443
Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002)This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work.In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest.The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present.This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience.While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Publisher: World Scientific
ISBN: 9814569062
Category : Biography & Autobiography
Languages : en
Pages : 443
Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002)This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work.In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest.The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present.This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience.While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
A Biography of Paul Berg
Author: Errol C. Friedberg
Publisher: World Scientific Publishing Company
ISBN: 9789814569040
Category : Biochemists
Languages : en
Pages : 0
Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work. In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest. The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present. This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience. While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Publisher: World Scientific Publishing Company
ISBN: 9789814569040
Category : Biochemists
Languages : en
Pages : 0
Book Description
With a Foreword by Sydney Brenner (Nobel laureate in Physiology or Medicine, 2002) This biography details the life of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's life from birth, in 1926, to the present, with special emphasis on his enormous scientific contributions, including being the first to develop technology that led to gene cloning science. In 1980, Berg received a Nobel Prize in chemistry for this work. In addition to his contributions in the research laboratory, Berg orchestrated and oversaw a historic meeting at Asilomar, California that centered on a threatening controversy surrounding the perception by some of the harmful potential of recombinant DNA technology. This meeting did much to forestall this controversy and to put in place the regulation of recombinant DNA work, thus putting fears to rest. The recombinant DNA controversy was a historic outcome of the discovery of gene cloning. Notably, it represented a paramount example of scientific foresight and due diligence by the scientific community, rather than by regulatory entities in the United States and many other countries. The ultimate acceptance of gene/DNA cloning led to a new era of modern biology that thrives to the present. This book is aimed primarily at scientists and those in training. The book strives to simply provide information for the general reader, but is not specifically tailored for a general reading audience. While many books cover the recombinant DNA controversy, none have satisfactorily addressed this historic period and are often contradictory about the many who's, where's, and why's involved. Additionally, the great majority of these were written by non-scientists. This biography of Paul Berg provides access to numerous archived letters and documents at Stanford University not previously addressed, and to the chronology of events as recalled and documented by him, as well as other key personalities, many of whom were interviewed.
Science for the People
Author: Sigrid Schmalzer
Publisher:
ISBN: 9781625343178
Category : Science
Languages : en
Pages : 0
Book Description
For the first time, this book compiles original documents from Science for the People, the most important radical science movement in U.S. history. Between 1969 and 1989, Science for the People mobilized American scientists, teachers, and students to practice a socially and economically just science, rather than one that served militarism and corporate profits. Through research, writing, protest, and organizing, members sought to demystify scientific knowledge and embolden "the people" to take science and technology into their own hands. The movement's numerous publications were crucial to the formation of science and technology studies, challenging mainstream understandings of science as "neutral" and instead showing it as inherently political. Its members, some at prominent universities, became models for politically engaged science and scholarship by using their knowledge to challenge, rather than uphold, the social, political, and economic status quo. Highlighting Science for the People's activism and intellectual interventions in a range of areas -- including militarism, race, gender, medicine, agriculture, energy, and global affairs -- this volume offers vital contributions to today's debates on science, justice, democracy, sustainability, and political power.
Publisher:
ISBN: 9781625343178
Category : Science
Languages : en
Pages : 0
Book Description
For the first time, this book compiles original documents from Science for the People, the most important radical science movement in U.S. history. Between 1969 and 1989, Science for the People mobilized American scientists, teachers, and students to practice a socially and economically just science, rather than one that served militarism and corporate profits. Through research, writing, protest, and organizing, members sought to demystify scientific knowledge and embolden "the people" to take science and technology into their own hands. The movement's numerous publications were crucial to the formation of science and technology studies, challenging mainstream understandings of science as "neutral" and instead showing it as inherently political. Its members, some at prominent universities, became models for politically engaged science and scholarship by using their knowledge to challenge, rather than uphold, the social, political, and economic status quo. Highlighting Science for the People's activism and intellectual interventions in a range of areas -- including militarism, race, gender, medicine, agriculture, energy, and global affairs -- this volume offers vital contributions to today's debates on science, justice, democracy, sustainability, and political power.