Author: Bert Bammens
Publisher: Leuven University Press
ISBN: 9789058674821
Category : Medical
Languages : en
Pages : 276

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Book Description

Author: Severin Ringoir
Publisher: Springer Science & Business Media
ISBN: 1468454455
Category : Science
Languages : en
Pages : 292

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Book Description
The present book contains the Proceedings of a two day Symposium on Uremic Toxins organized at the University of Ghent in Belgium. A series of guest lectures, free communications and posters have been presented. An international audience of 163 scientists from 16 nationalities listened to and discussed extensively a spectrum of topics brought forward by colleagues and researchers who worked for many years in the field of Uremic Toxins. There is a striking contrast between all the new dialysis strategies available in the work to "clean" the uremic patients and the almost non-progression of our knowledge on uremic toxins in the past decade. In this sense the symposium was felt by all participants as a new start for the research in the biochemical field of the definition of uremia. If the present volume would stimulate new work in this field in order to define uremia, or identify the uremic toxins, the purpose of the organizers would be maximally fulfilled.

Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805579381
Category : Medical
Languages : en
Pages : 377

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Book Description
Hemodialysis therapy has become a well-established form of renal replacement, and due to continuous improvements in technology, a series of new biomaterials and techniques for the clinical routine have been developed. Nevertheless, cardiovascular disorders in hemodialysis and uremia represent one of the most important aspects of modern nephrological care. This publication is therefore dedicated to cardiovascular risk factors, the role of the endothelium, problems related to mineral disorders and finally to the possible impact of new technologies on the final outcome in hemodialysis. Being a state-of-the-art appraisal of today's technology and current issues in hemodialysis with special regard to cardiovascular disorders and risk factors, this book is a synthesis between an educational effort aimed at the newer generations of physicians and nurses in the field of hemodialysis and a state-of-the-art description of the most advanced technologies in this field. At the same time, the lessons learned from large international trials, either already completed or to be completed in the years to come, are presented.

Author: Alan S. L. Yu
Publisher: Elsevier Health Sciences
ISBN: 0323550851
Category : Medical
Languages : en
Pages : 3753

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Book Description
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Author: Edgar Lerma
Publisher: Lippincott Williams & Wilkins
ISBN: 1496348494
Category : Medical
Languages : en
Pages : 1793

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Book Description
Improve your patients’ quality of life with evidence-based, practical guidance on every aspect of today’s dialysis. For more than 20 years, Henrich’s Principles and Practice of Dialysis has been the go-to resource for comprehensive, accessible information on the challenges of managing the wide variety of patients who receive dialysis. This Fifth Edition brings you fully up to date with new chapters, a new eBook edition, two new editors and new contributors who offer practical experience and a fresh perspective. Clearly written and unique in scope, it helps you meet the growing demand for this procedure by providing a solid foundation in both basic science and clinical application.

Author: Hideyuki Saito
Publisher: Springer Nature
ISBN: 9811577935
Category : Medical
Languages : en
Pages : 180

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Book Description
This book describes the latest research on the gut-kidney axis of ureic solutes; the toxico-pathological mechanisms of uremic toxin-induced organ failure, including kidney and cardiovascular tissue; and the preventive therapeutic strategies for uremia and related organ failure associated with kidney injuries and diseases. Retained uremic toxins cause a variety of symptoms, such as hypertension, fatigue, renal anemia, osteoporosis and neurologic impairment, which are apparent in chronic kidney disease (CKD) patients. The human gastrointestinal tract contains trillions of microorganisms, referred to as gut microbiota, which support the host metabolism by producing nutrients, such as vitamins and short-chain fatty acids. However, they also produce various harmful uremic toxins that show renal and cardiovascular toxicity, and correlate with an increased mortality in CKD patients. The composition and balance of gut microbiota are associated with the accumulation of uremic toxins and the pathophysiology of CKD, and as such are being considered for a novel therapeutic strategy.

Author: Joel D. Kopple
Publisher: Academic Press
ISBN: 0128185414
Category : Medical
Languages : en
Pages : 1041

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Book Description
Nutritional Management of Renal Disease, Fourth Edition, offers in-depth reviews of the metabolic and nutritional disorders prevalent in patients with renal disease and serves as an in-depth reference source concerning nutrition and kidney disease. This classic translational reference provides correct diagnosis - and therefore correct treatment - of renal, metabolic, and nutritional disorders. Nephrologists, diebetologists, endocrinologists, dieticians, and nutritionists depend on a strong understanding of the molecular basis for the disease. This fourth edition includes thorough new case reports, offering expert advice on how to use the latest research and clinical findings in counseling patients about dietary and lifestyle options. Readers gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient. - Includes the latest comprehensive KDOQI clinical practice guidelines for the nutritional management of kidney disease from the National Kidney Foundation and the Academy of Nutrition and Dietetics, covering recommendations for each essential nutrient, as well as for some nonessential nutrients - Presents a comprehensive, translational look at all aspects of metabolic and nutritional disorders in one reference - Provides a common language for nephrologists, nutritionists, endocrinologists, and other interested physicians to assimilate information and discuss the underlying research and translation of best practices for the nutritional management and prevention of renal disease - Saves clinicians and researchers time in quickly accessing the very latest details on nutritional practice as opposed to searching through thousands of journal articles

Author: Paolo Arosio
Publisher: MDPI
ISBN: 3039280821
Category : Science
Languages : en
Pages : 472

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Book Description
Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.

Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805585667
Category : Medical
Languages : en
Pages : 289

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Book Description
Ronco and Cruz (both Dept. of Nephrology, San Bortolo Hospital, Vicenza, Italy) present a collection of 36 articles focusing on the physiological aspects of hemodialysis treatments as well as practical questions in the dialysis unit. Originally created as a supplement to the lectures presented at the 17th Annual International Course on Hemodialysis, a three-day event held in Vicenza, Italy, the text provides a valuable reference for the clinician interested in keeping up on developments in the field of hemodialysis. Thirty-six contributions by some 80 international academics, researchers, and practitioners are organized into ten sections covering dialysis technology, vascular access, epidemiology and practice, inflammation, fluid management, uremic toxicity, treatment efficacy, advanced techniques, calcium/phosphate homeostasis, and correction of anemia.

Author: David Goldsmith
Publisher: Springer
ISBN: 331909162X
Category : Medical
Languages : en
Pages : 237

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Book Description
​​​​​​​​In modern medicine, the aging population is prone to many simultaneous cardiovascular (CV) risk factors which often produce co-incident pathology. Nowhere is this more obvious than in the interaction between Chronic Kidney Disease (CKD), Diabetes and diverse CV diseases (CVD). This is a complex and challenging area, as the presence of CKD/diabetes promotes CVD while also complicating its treatment. The emergence of CKD as a public health priority is one of the most challenging problems of modern medicine. It is now solidly established that renal dysfunction portends a high risk for cardiovascular disease. Cardiovascular diseases remains the main cause of death in western societies and the amplification of the death risk conveyed by coexisting CKD, even though still poorly understood, appears considerable. The bidirectional link that associates renal and cardiovascular diseases, the high risk of the death signalled by their coexistence and the considerable epidemiological burden imposed by this link is at the basis of the emergence of a new discipline aiming at making the borders between nephrology and cardiovascular medicine even more permeable than before. The term Cardio-Renal Syndrome was coined around 5 years ago to try to formalize this link, and act as a stimulus to interaction between clinical teams, researchers and others to achieve better management and outcomes for all. This book takes clinical presentations and clinical problems as its base, and then discuss the evidence for best management of common clinical problems as well as the reasons for the complex interplay between the cardiac and renal systems. Moreover, it addresses the issue of organizing healthcare to maximize the opportunities for prevention and best healthcare economic returns, building on cutting edge initiatives at the Karolinska, Stockholm. The book will be of immediate value and interest to all cardiologists and renal physicians.