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Author: Epie Boven
Publisher: CRC Press
ISBN: 1351085662
Category : Medical
Languages : en
Pages : 350
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Book Description
The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Author: Epie Boven
Publisher: CRC Press
ISBN: 1351085662
Category : Medical
Languages : en
Pages : 350
Get Book
Book Description
The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Author: Epie Boven
Publisher: CRC Press
ISBN: 9780849365317
Category : Medical
Languages : en
Pages : 352
Get Book
Book Description
The nude, athymic mouse (nu/nu) has become generally accepted as a valuable tool to study the biology and therapy of human cancers. This volume presents a critical review of the scientific merits of the animal as a recipient of human tumor tissue transplants. Important information is provided regarding biology, immunology, and measures for genetic and microbiological control of the nude mouse. The discussion of transplantation sites and transplantability of human tumor tissue to the animals includes both the description of host factors and the tumor type involved. The characterization and monitoring of xenografts is followed by a review on their possible application for studies in tumor biology, such as hormones, growth factors, drug resistance, tumor markers, and heterogeneity. Experimental therapy is dedicated to cytostatic agents, hormones, monoclonal antibodies, cytokines, differentiation inducers and radiotherapy. The book also provides critical remarks regarding the limitation of the nude-mouse tumor models. The Nude Mouse in Oncology Research will provide essential reference information for oncology researchers, researchers who work with the nude mouse on a regular basis, and pharmaceutical companies.
Author: Jorgen Fogh
Publisher: Elsevier
ISBN: 0323147348
Category : Science
Languages : en
Pages : 519
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Book Description
The Nude Mouse in Experimental and Clinical Research presents the state of knowledge regarding the nude mouse and its applications to different branches of scientific research. The research studies featured in this book emphasize the academic status of a broad range of subjects and techniques of nude mouse research. The text consists of 21 chapters, each discussing an important aspect of nude mouse research. Some chapters discuss the biological aspect such as physiology, genes, and breeding and mass production of the mouse. A number of the chapters also discuss the general observations of the mouse like histopathological observations and their background. The applications of the nude mouse to human tumor and cancer cell research are likewise given emphasis. This book will be of valuable importance to both students and researchers in the fields of medicine, biology, and pathology.
Author: Jørgen Fogh
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 616
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Book Description
Author: David P. Houchens
Publisher: Fischer Gustav Verlag GmbH & Company KG
ISBN:
Category : Medical
Languages : en
Pages : 326
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Book Description
Author: H. H. Fiebig
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 608
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Book Description
Author: S. Sparrow
Publisher: Springer
ISBN: 1349050148
Category : Medical
Languages : en
Pages : 245
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Book Description
Author: Wolfgang Arnold
Publisher: S. Karger AG (Switzerland)
ISBN:
Category : Medical
Languages : en
Pages : 252
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Book Description
The classic immunodeficient mutants nude, scid and rnu have an important function in experimental cancer research: they allow unique methods of investigation and provide data of clinical relevance. This volume presents the state of the art of research work based on the use of these immunodeficient animal models. One section is dedicated to the biological aspects and immunological properties of immunodeficient mutants. Another part includes articles on xenogenous transplantation of human tumors, focusing on the establishment of transplantable lines, growth characteristics and tumor markers. Special attention is given to new approaches in the fields of chemotherapy, radiation therapy and immunotherapy. Various contributors consider in vitro methods as alternative models. In addition to current data, this publication contains useful technical and methodological information and is therefore valuable not only for specialists but also for scientists entering the field of experimental cancer research.
Author: Mice
Publisher:
ISBN: 9780895741547
Category :
Languages : en
Pages :
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Book Description
Author: Jørgen Rygaard
Publisher:
ISBN:
Category : Immune response
Languages : en
Pages : 52
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Book Description
443 numbered references to literature (mostly journal articles). "Bibliography is based on the questionnaire sent out by the Nude Mouse Secretariat in the autumn of 1975. To this is added references collected elsewhere." Alphabetical arrangement by primary authors. Entries include bibliographical information. Subject index.
