Author: Kersten T. Hall
Publisher: OUP Oxford
ISBN: 019100989X
Category : Science
Languages : en
Pages : 334
Book Description
Sir Isaac Newton once declared that his momentous discoveries were only made thanks to having 'stood on the shoulders of giants'. The same might also be said of the scientists James Watson and Francis Crick. Their discovery of the structure of DNA was, without doubt, one of the biggest scientific landmarks in history and, thanks largely to the success of Watson's best-selling memoir 'The Double Helix', there might seem to be little new to say about this story. But much remains to be said about the particular 'giants' on whose shoulders Watson and Crick stood. Of these, the crystallographer Rosalind Franklin, whose famous X-ray diffraction photograph known as 'Photo 51' provided Watson and Crick with a vital clue, is now well recognised. Far less well known is the physicist William T. Astbury who, working at Leeds in the 1930s on the structure of wool for the local textile industry, pioneered the use of X-ray crystallography to study biological fibres. In so doing, he not only made the very first studies of the structure of DNA culminating in a photo almost identical to Franklin's 'Photo 51', but also founded the new science of 'molecular biology'. Yet whilst Watson and Crick won the Nobel Prize, Astbury has largely been forgotten. The Man in the Monkeynut Coat tells the story of this neglected pioneer, showing not only how it was thanks to him that Watson and Crick were not left empty-handed, but also how his ideas transformed biology leaving a legacy which is still felt today.
The Man in the Monkeynut Coat
Author: Kersten T. Hall
Publisher: OUP Oxford
ISBN: 019100989X
Category : Science
Languages : en
Pages : 334
Book Description
Sir Isaac Newton once declared that his momentous discoveries were only made thanks to having 'stood on the shoulders of giants'. The same might also be said of the scientists James Watson and Francis Crick. Their discovery of the structure of DNA was, without doubt, one of the biggest scientific landmarks in history and, thanks largely to the success of Watson's best-selling memoir 'The Double Helix', there might seem to be little new to say about this story. But much remains to be said about the particular 'giants' on whose shoulders Watson and Crick stood. Of these, the crystallographer Rosalind Franklin, whose famous X-ray diffraction photograph known as 'Photo 51' provided Watson and Crick with a vital clue, is now well recognised. Far less well known is the physicist William T. Astbury who, working at Leeds in the 1930s on the structure of wool for the local textile industry, pioneered the use of X-ray crystallography to study biological fibres. In so doing, he not only made the very first studies of the structure of DNA culminating in a photo almost identical to Franklin's 'Photo 51', but also founded the new science of 'molecular biology'. Yet whilst Watson and Crick won the Nobel Prize, Astbury has largely been forgotten. The Man in the Monkeynut Coat tells the story of this neglected pioneer, showing not only how it was thanks to him that Watson and Crick were not left empty-handed, but also how his ideas transformed biology leaving a legacy which is still felt today.
Publisher: OUP Oxford
ISBN: 019100989X
Category : Science
Languages : en
Pages : 334
Book Description
Sir Isaac Newton once declared that his momentous discoveries were only made thanks to having 'stood on the shoulders of giants'. The same might also be said of the scientists James Watson and Francis Crick. Their discovery of the structure of DNA was, without doubt, one of the biggest scientific landmarks in history and, thanks largely to the success of Watson's best-selling memoir 'The Double Helix', there might seem to be little new to say about this story. But much remains to be said about the particular 'giants' on whose shoulders Watson and Crick stood. Of these, the crystallographer Rosalind Franklin, whose famous X-ray diffraction photograph known as 'Photo 51' provided Watson and Crick with a vital clue, is now well recognised. Far less well known is the physicist William T. Astbury who, working at Leeds in the 1930s on the structure of wool for the local textile industry, pioneered the use of X-ray crystallography to study biological fibres. In so doing, he not only made the very first studies of the structure of DNA culminating in a photo almost identical to Franklin's 'Photo 51', but also founded the new science of 'molecular biology'. Yet whilst Watson and Crick won the Nobel Prize, Astbury has largely been forgotten. The Man in the Monkeynut Coat tells the story of this neglected pioneer, showing not only how it was thanks to him that Watson and Crick were not left empty-handed, but also how his ideas transformed biology leaving a legacy which is still felt today.
The Man in the Monkeynut Coat
Author: Kersten T. Hall
Publisher: Oxford University Press (UK)
ISBN: 0198704593
Category : Biography & Autobiography
Languages : en
Pages : 255
Book Description
Tells the story of the English physicist and molecular biologist William T. Astbury and how his work forms a previously untold chapter in the story of the discovery of the structure of DNA.
Publisher: Oxford University Press (UK)
ISBN: 0198704593
Category : Biography & Autobiography
Languages : en
Pages : 255
Book Description
Tells the story of the English physicist and molecular biologist William T. Astbury and how his work forms a previously untold chapter in the story of the discovery of the structure of DNA.
The Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the Discovery of DNA's Double Helix
Author: Howard Markel
Publisher: W. W. Norton & Company
ISBN: 1324002247
Category : Science
Languages : en
Pages : 526
Book Description
An NPR Best Book of the Year An authoritative history of the race to unravel DNA’s structure, by one of our most prominent medical historians. James Watson and Francis Crick’s 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it—and why were they the ones who succeeded? In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel. The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised. A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.
Publisher: W. W. Norton & Company
ISBN: 1324002247
Category : Science
Languages : en
Pages : 526
Book Description
An NPR Best Book of the Year An authoritative history of the race to unravel DNA’s structure, by one of our most prominent medical historians. James Watson and Francis Crick’s 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it—and why were they the ones who succeeded? In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel. The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised. A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.
Strange Glow
Author: Timothy J. Jorgensen
Publisher: Princeton University Press
ISBN: 0691178348
Category : Science
Languages : en
Pages : 506
Book Description
The fascinating science and history of radiation More than ever before, radiation is a part of our modern daily lives. We own radiation-emitting phones, regularly get diagnostic x-rays, such as mammograms, and submit to full-body security scans at airports. We worry and debate about the proliferation of nuclear weapons and the safety of nuclear power plants. But how much do we really know about radiation? And what are its actual dangers? An accessible blend of narrative history and science, Strange Glow describes mankind's extraordinary, thorny relationship with radiation, including the hard-won lessons of how radiation helps and harms our health. Timothy Jorgensen explores how our knowledge of and experiences with radiation in the last century can lead us to smarter personal decisions about radiation exposures today. Jorgensen introduces key figures in the story of radiation—from Wilhelm Roentgen, the discoverer of x-rays, and pioneering radioactivity researchers Marie and Pierre Curie, to Thomas Edison and the victims of the recent Fukushima Daiichi nuclear power plant accident. Tracing the most important events in the evolution of radiation, Jorgensen explains exactly what radiation is, how it produces certain health consequences, and how we can protect ourselves from harm. He also considers a range of practical scenarios such as the risks of radon in our basements, radiation levels in the fish we eat, questions about cell-phone use, and radiation's link to cancer. Jorgensen empowers us to make informed choices while offering a clearer understanding of broader societal issues. Investigating radiation's benefits and risks, Strange Glow takes a remarkable look at how, for better or worse, radiation has transformed our society.
Publisher: Princeton University Press
ISBN: 0691178348
Category : Science
Languages : en
Pages : 506
Book Description
The fascinating science and history of radiation More than ever before, radiation is a part of our modern daily lives. We own radiation-emitting phones, regularly get diagnostic x-rays, such as mammograms, and submit to full-body security scans at airports. We worry and debate about the proliferation of nuclear weapons and the safety of nuclear power plants. But how much do we really know about radiation? And what are its actual dangers? An accessible blend of narrative history and science, Strange Glow describes mankind's extraordinary, thorny relationship with radiation, including the hard-won lessons of how radiation helps and harms our health. Timothy Jorgensen explores how our knowledge of and experiences with radiation in the last century can lead us to smarter personal decisions about radiation exposures today. Jorgensen introduces key figures in the story of radiation—from Wilhelm Roentgen, the discoverer of x-rays, and pioneering radioactivity researchers Marie and Pierre Curie, to Thomas Edison and the victims of the recent Fukushima Daiichi nuclear power plant accident. Tracing the most important events in the evolution of radiation, Jorgensen explains exactly what radiation is, how it produces certain health consequences, and how we can protect ourselves from harm. He also considers a range of practical scenarios such as the risks of radon in our basements, radiation levels in the fish we eat, questions about cell-phone use, and radiation's link to cancer. Jorgensen empowers us to make informed choices while offering a clearer understanding of broader societal issues. Investigating radiation's benefits and risks, Strange Glow takes a remarkable look at how, for better or worse, radiation has transformed our society.
Landmark Experiments in Molecular Biology
Author: Michael Fry
Publisher: Academic Press
ISBN: 012802108X
Category : Science
Languages : en
Pages : 572
Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. - Includes detailed analysis of classically designed and executed experiments - Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries - Provides critical analysis of the history of molecular biology to inform the future of scientific discovery - Examines the machinery of inheritance and biological information handling
Publisher: Academic Press
ISBN: 012802108X
Category : Science
Languages : en
Pages : 572
Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. - Includes detailed analysis of classically designed and executed experiments - Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries - Provides critical analysis of the history of molecular biology to inform the future of scientific discovery - Examines the machinery of inheritance and biological information handling
A Cultural History of Chemistry in the Modern Age
Author: Peter J. T. Morris
Publisher: Bloomsbury Publishing
ISBN: 1350251569
Category : History
Languages : en
Pages : 289
Book Description
A Cultural History of Chemistry in the Modern Age covers the period from 1914 to the present. The impact of chemistry and the chemical industry on science, war, society, and the economy has made this era the “Chemical Age”. Having prospered in the West, chemical science spread across the globe and slowly became more diversified in terms of its ethnic and gendered mix. After flourishing for sixty years, the chemical industry was impacted by the Oil Crisis of the 1970s and became almost invisible in the West. While the industry has clearly delivered many benefits to society-such as new materials and better drugs-it has been excoriated by critics for its impact on the environment. The 6 volume set of the Cultural History of Chemistry presents the first comprehensive history from the Bronze Age to today, covering all forms and aspects of chemistry and its ever-changing social context. The themes covered in each volume are theory and concepts; practice and experiment; laboratories and technology; culture and science; society and environment; trade and industry; learning and institutions; art and representation. Peter J. T. Morris is Honorary Research Associate at the Science Museum, London, and at University College London, UK Volume 6 in the Cultural History of Chemistry set. General Editors: Peter J. T. Morris, University College London, UK, and Alan Rocke, Case Western Reserve University, USA.
Publisher: Bloomsbury Publishing
ISBN: 1350251569
Category : History
Languages : en
Pages : 289
Book Description
A Cultural History of Chemistry in the Modern Age covers the period from 1914 to the present. The impact of chemistry and the chemical industry on science, war, society, and the economy has made this era the “Chemical Age”. Having prospered in the West, chemical science spread across the globe and slowly became more diversified in terms of its ethnic and gendered mix. After flourishing for sixty years, the chemical industry was impacted by the Oil Crisis of the 1970s and became almost invisible in the West. While the industry has clearly delivered many benefits to society-such as new materials and better drugs-it has been excoriated by critics for its impact on the environment. The 6 volume set of the Cultural History of Chemistry presents the first comprehensive history from the Bronze Age to today, covering all forms and aspects of chemistry and its ever-changing social context. The themes covered in each volume are theory and concepts; practice and experiment; laboratories and technology; culture and science; society and environment; trade and industry; learning and institutions; art and representation. Peter J. T. Morris is Honorary Research Associate at the Science Museum, London, and at University College London, UK Volume 6 in the Cultural History of Chemistry set. General Editors: Peter J. T. Morris, University College London, UK, and Alan Rocke, Case Western Reserve University, USA.
Women Who Changed the World [4 volumes]
Author: Candice Goucher
Publisher: Bloomsbury Publishing USA
ISBN: 1440868255
Category : History
Languages : en
Pages : 1379
Book Description
This indispensable reference work provides readers with the tools to reimagine world history through the lens of women's lived experiences. Learning how women changed the world will change the ways the world looks at the past. Women Who Changed the World: Their Lives, Challenges, and Accomplishments through History features 200 biographies of notable women and offers readers an opportunity to explore the global past from a gendered perspective. The women featured in this four-volume set cover the full sweep of history, from our ancestral forbearer "Lucy" to today's tennis phenoms Venus and Serena Williams. Every walk of life is represented in these pages, from powerful monarchs and politicians to talented artists and writers, from inquisitive scientists to outspoken activists. Each biography follows a standardized format, recounting the woman's life and accomplishments, discussing the challenges she faced within her particular time and place in history, and exploring the lasting legacy she left. A chronological listing of biographies makes it easy for readers to zero in on particular time periods, while a further reading list at the end of each essay serves as a gateway to further exploration and study. High-interest sidebars accompany many of the biographies, offering more nuanced glimpses into the lives of these fascinating women.
Publisher: Bloomsbury Publishing USA
ISBN: 1440868255
Category : History
Languages : en
Pages : 1379
Book Description
This indispensable reference work provides readers with the tools to reimagine world history through the lens of women's lived experiences. Learning how women changed the world will change the ways the world looks at the past. Women Who Changed the World: Their Lives, Challenges, and Accomplishments through History features 200 biographies of notable women and offers readers an opportunity to explore the global past from a gendered perspective. The women featured in this four-volume set cover the full sweep of history, from our ancestral forbearer "Lucy" to today's tennis phenoms Venus and Serena Williams. Every walk of life is represented in these pages, from powerful monarchs and politicians to talented artists and writers, from inquisitive scientists to outspoken activists. Each biography follows a standardized format, recounting the woman's life and accomplishments, discussing the challenges she faced within her particular time and place in history, and exploring the lasting legacy she left. A chronological listing of biographies makes it easy for readers to zero in on particular time periods, while a further reading list at the end of each essay serves as a gateway to further exploration and study. High-interest sidebars accompany many of the biographies, offering more nuanced glimpses into the lives of these fascinating women.
Insulin - the Crooked Timber
Author: Kersten T. Hall
Publisher: Oxford University Press
ISBN: 0192855387
Category : Medical
Languages : en
Pages : 476
Book Description
Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.
Publisher: Oxford University Press
ISBN: 0192855387
Category : Medical
Languages : en
Pages : 476
Book Description
Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. To mark the centenary of this landmark in medicine, this book charts the journey of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, and which earned the founders of US biotech company Genentech a small fortune. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, Insulin - The Crooked Timber reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes and heroines. It discusses in detail the circumstances of Canadian scientist Frederick Banting whose award of the 1923 Nobel Prize for this life-saving discovery proved to be both a blessing and a curse for him and explores how the human story behind this discovery still remains one of ongoing political and scientific controversy. The book is the result of the author's own shocking diagnosis with Type 1 diabetes and its story reminds us all of what technology can - and cannot do - for us. As the world struggles to emerge from the COVID-19 pandemic and face future challenges such as climate change, the lessons that we can learn from the story of insulin have never been more important.
The Whys of a Scientific Life
Author: John R. Helliwell
Publisher: CRC Press
ISBN: 0429752792
Category : Medical
Languages : en
Pages : 96
Book Description
The first in the Focus Series on Global Science Education, The Whys of a Scientific Life examines why scientists do what they do. Working from a diverse background in scientific research, including academic departments of physics and chemistry, as well as the scientific civil service, the author describes the choices scientists make. Fundamentally, a scientist asks questions based on curiosity. In addition, the environment is very important. By influencing their elected governments, society itself shapes the scientific research that is undertaken by scientists. This book follows on naturally from the author’s last book, Skills for a Scientific Life, which is a how-to guide for scientists and those that aspire to engage in science as a career. Key Features: User friendly and concise, this text dissects the whys of science and discovery The author has outstanding experience in mentoring science students and staff, and also in outreach activities for the public and students of all ages including schools The final chapter emphasises the joys of the scientist in research
Publisher: CRC Press
ISBN: 0429752792
Category : Medical
Languages : en
Pages : 96
Book Description
The first in the Focus Series on Global Science Education, The Whys of a Scientific Life examines why scientists do what they do. Working from a diverse background in scientific research, including academic departments of physics and chemistry, as well as the scientific civil service, the author describes the choices scientists make. Fundamentally, a scientist asks questions based on curiosity. In addition, the environment is very important. By influencing their elected governments, society itself shapes the scientific research that is undertaken by scientists. This book follows on naturally from the author’s last book, Skills for a Scientific Life, which is a how-to guide for scientists and those that aspire to engage in science as a career. Key Features: User friendly and concise, this text dissects the whys of science and discovery The author has outstanding experience in mentoring science students and staff, and also in outreach activities for the public and students of all ages including schools The final chapter emphasises the joys of the scientist in research
The Black Box of Biology
Author: Michel Morange
Publisher: Harvard University Press
ISBN: 0674281365
Category : Science
Languages : en
Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Publisher: Harvard University Press
ISBN: 0674281365
Category : Science
Languages : en
Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.