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Author: [Anonymus AC08468611]
Publisher:
ISBN: 9783527600410
Category : Industrial toxicology
Languages : de
Pages :
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Book Description
The online edition of the MAK-Collection includes the publications of four serial publications in two languages, English and German: (1) MAK Value Documentations / Gesundheitsschädliche Arbeitsstoffe. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten und Einstufungen; (2) BAT Value Documentations / Biologische Arbeitsstoff-Toleranz-Werte, Expositionsäquivalente für krebserzeugende Arbeitsstoffe, Biologische Leitwerte und Biologische Arbeitsstoff-Referenzwerte. Arbeitsmedizinisch-toxikologische Begründungen; (3) Air Monitoring Methods / Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe. Luftanalysen; (4) Biomonitoring Methods / Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe. Analysen in biologischem Material. - "The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) supports global open access to the online editions of the complete publications of the MAK Commission in English and in German language on Wiley Online Library, including all future updates and additions."
![[The MAK collection for occupational health and safety / 1 ] ; The MAK collection for occupational health and safety. Pt. 1, MAK value documentations PDF](https://books.google.com/books/content/images/frontcover/q5oWzQEACAAJ?fife=w80-h100)
Author: [Anonymus AC08468611]
Publisher:
ISBN: 9783527600410
Category : Industrial toxicology
Languages : de
Pages :
Get Book Here
Book Description
The online edition of the MAK-Collection includes the publications of four serial publications in two languages, English and German: (1) MAK Value Documentations / Gesundheitsschädliche Arbeitsstoffe. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten und Einstufungen; (2) BAT Value Documentations / Biologische Arbeitsstoff-Toleranz-Werte, Expositionsäquivalente für krebserzeugende Arbeitsstoffe, Biologische Leitwerte und Biologische Arbeitsstoff-Referenzwerte. Arbeitsmedizinisch-toxikologische Begründungen; (3) Air Monitoring Methods / Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe. Luftanalysen; (4) Biomonitoring Methods / Analytische Methoden zur Prüfung gesundheitsschädlicher Arbeitsstoffe. Analysen in biologischem Material. - "The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) supports global open access to the online editions of the complete publications of the MAK Commission in English and in German language on Wiley Online Library, including all future updates and additions."
Author: Andrea Hartwig
Publisher: John Wiley & Sons
ISBN: 3527323082
Category : Technology & Engineering
Languages : en
Pages : 318
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Book Description
This volume provides documentations for the established MAK values (maximum workplace concentrations) of selected occupational toxicants, including an authoritative review of the available toxicological studies and data. For each substance, the toxic effects, mechanisms and modes of action, toxicogenetics and metabolism, effects in man and animals are described. In addition, the carcinogenic, germ-cell mutagenic, sensitizing or skin-resorptive effects as well as their toxicity to the reproductive system are evaluated, plus basic physico-chemical data are provided. The documentations are thus not only essential for the application of MAK values but also provide a concise toxicological overview for each substance.
Author: Hans Drexler
Publisher: Wiley-VCH
ISBN:
Category : Medical
Languages : en
Pages : 256
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Book Description
This volume provides the documentations for the established BAT values and EKA, as well as for further biological exposure values, including an authoritative review of the available toxicological studies and data. For each substance, the metabolism and pharmacokinetics, critical toxicity, exposure and effects, suitable indicators of internal exposure, the evaluation of the BAT value and the correct interpretation of data are described. The basic physico-chemical data are also provided, making the documentations not only essential for the application of BAT values and EKA, but also provide a concise overview of biological monitoring for each substance.
Author: Helmut Greim
Publisher: Wiley-VCH
ISBN: 9783527319589
Category : Science
Languages : en
Pages : 336
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Book Description
This volume provides documentations for the established MAK values (maximum workplace concentrations) of selected occupational toxicants, including an authoritative review of the available toxicological studies and data. For each substance, the toxic effects, mechanisms and modes of action, toxicogenetics and metabolism, effects in man and animals are described. In addition, the carcinogenic, germ-cell mutagenic, sensitizing or skin-resorptive effects as well as their toxicity to the reproductive system are evaluated, plus basic physico-chemical data are provided. The documentations are thus not only essential for the application of MAK values but also provide a concise toxicological overview for each substance.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309267366
Category : Medical
Languages : en
Pages : 199
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Book Description
Lead is a ubiquitous metal in the environment, and its adverse effects on human health are well documented. Lead interacts at multiple cellular sites and can alter protein function in part through binding to amino acid sulfhydryl and carboxyl groups on a wide variety of structural and functional proteins. In addition, lead mimics calcium and other divalent cations, and it induces the increased production of cytotoxic reactive oxygen species. Adverse effects associated with lead exposure can be observed in multiple body systems, including the nervous, cardiovascular, renal, hematologic, immunologic, and reproductive systems. Lead exposure is also known to induce adverse developmental effects in utero and in the developing neonate. Lead poses an occupational health hazard, and the Occupational Safety and Health Administration (OSHA) developed a lead standard for general industry that regulates many workplace exposures to this metal. The standard was promulgated in 1978 and encompasses several approaches for reducing exposure to lead, including the establishment of a permissible exposure limit (PEL) of 50 μg/m3 in air (an 8-hour time-weighted average [TWA]), exposure guidelines for instituting medical surveillance, guidelines for removal from and return to work, and other risk-management strategies. An action level of 30 μg/m3 (an 8-hour TWA) for lead was established to trigger medical surveillance in employees exposed above that level for more than 30 days per year. Another provision is that any employee who has a blood lead level (BLL) of 60 μg/dL or higher or three consecutive BLLs averaging 50 μg/dL or higher must be removed from work involving lead exposure. An employee may resume work associated with lead exposure only after two BLLs are lower than 40 μg/dL. Thus, maintaining BLLs lower than 40 μg/dL was judged by OSHA to protect workers from adverse health effects. The OSHA standard also includes a recommendation that BLLs of workers who are planning a pregnancy be under 30μg/dL. In light of knowledge about the hazards posed by occupational lead exposure, the Department of Defense (DOD) asked the National Research Council to evaluate potential health risks from recurrent lead exposure of firing-range personnel. Specifically, DOD asked the National Research Council to determine whether current exposure standards for lead on DOD firing ranges protect its workers adequately.The committee also considered measures of cumulative lead dose. Potential Health Risks to DOD Firing-Range Personnel from Recurrent Lead Exposure will help to inform decisions about setting new air exposure limits for lead on firing ranges, about whether to implement limits for surface contamination, and about how to design lead-surveillance programs for range personnel appropriately.
Author:
Publisher: World Health Organization
ISBN: 9240009523
Category : Nature
Languages : en
Pages : 188
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Book Description
Author: Helmut Greim
Publisher: John Wiley & Sons
ISBN: 1119135931
Category : Science
Languages : en
Pages : 862
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Book Description
Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.
Author: Nader Rifai
Publisher: Elsevier Health Sciences
ISBN: 0323548482
Category : Medical
Languages : en
Pages : 1888
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Book Description
The Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 6th Edition provides the most current and authoritative guidance on selecting, performing, and evaluating the results of new and established laboratory tests. This classic clinical chemistry reference offers encyclopedic coverage detailing everything you need to know, including: analytical criteria for the medical usefulness of laboratory tests, variables that affect tests and results, laboratory medicine, applications of statistical methods, and most importantly clinical utility and interpretation of laboratory tests. It is THE definitive reference in clinical chemistry and molecular diagnostics, now fully searchable and with quarterly content updates, podcasts, clinical cases, animations, and extended content online through Expert Consult. Analytical criteria focus on the medical usefulness of laboratory procedures. Reference ranges show new approaches for establishing these ranges — and provide the latest information on this topic. Lab management and costs gives students and chemists the practical information they need to assess costs, allowing them to do their job more efficiently and effectively. Statistical methods coverage provides you with information critical to the practice of clinical chemistry. Internationally recognized chapter authors are considered among the best in their field. Two-color design highlights important features, illustrations, and content to help you find information easier and faster. NEW! Internationally recognized chapter authors are considered among the best in their field. NEW! Expert Consult features fully searchable text, quarterly content updates, clinical case studies, animations, podcasts, atlases, biochemical calculations, multiple-choice questions, links to Medline, an image collection, and audio interviews. You will now enjoy an online version making utility of this book even greater. UPDATED! Expanded Molecular Diagnostics section with 12 chapters that focus on emerging issues and techniques in the rapidly evolving and important field of molecular diagnostics and genetics ensures this text is on the cutting edge and of the most value. NEW! Comprehensive list of Reference Intervals for children and adults with graphic displays developed using contemporary instrumentation. NEW! Standard and international units of measure make this text appropriate for any user — anywhere in the world. NEW! 22 new chapters that focus on applications of mass spectrometry, hematology, transfusion medicine, microbiology, biobanking, biomarker utility in the pharmaceutical industry and more! NEW! Expert senior editors, Nader Rifai, Carl Wittwer and Rita Horvath, bring fresh perspectives and help ensure the most current information is presented. UPDATED! Thoroughly revised and peer-reviewed chapters provide you with the most current information possible.
Author: Mahendra Rai
Publisher: Springer
ISBN: 3030051447
Category : Medical
Languages : en
Pages : 370
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Book Description
The environment is prone to suffer pollution and toxic insult from generations of nanomaterials as well from accidental releases during production, transportation, and disposal operations. The NMs could interact with and cause adverse biological effects at cellular, subcellular, and molecular levels. Assessing potential environmental/ecological risks requires quality information on transport and fate of nanoparticles in the environment, exposures and vulnerabilities of organisms to the nanomaterials and standard methods for assessing toxicity for aquatic or terrestrial organisms and human health. The systematic risk characterization and evaluation of the safety of nanomaterials require a multidisciplinary approach and convergence of knowledge and efforts from researchers and experts from toxicology, biotechnology, materials science, chemistry, physics, engineering, and other branches of life sciences. Although studies are beginning to appear in the literature addressing the toxicity of various nanomaterials and their potential for exposure, at this stage definitive statements regarding the impacts of nanomaterials on human health and the environment remain sketchy requiring an increased level of precautions with regard to nanomaterials, as has happened with other emerging contaminants and technologies (e.g., biotechnology). The need for an increased level of understanding the perception of risk and of benefits will vary and is likely to influence public, regulatory, and non-governmental activities regarding risk and benefit evaluations. Systematic identification and assessment of the risks posed by any new technology are essential. A prudent, integrated, and holistic approach is required to develop best practices based on the scientific understanding about what we know and what we don’t know but need to know. Nanomaterials addresses key issues of ecotoxicological actions and effects of nanomaterials on life and environment, their threats, vulnerability, risks, and public perception. The readers learn to read bad news objectively and think about and search for ecological ‘green’ solutions to current environmental and ecological problems with blue, grey, brown, and red shades for building a sustainable ecosystem. It shows how this molecular terrain is a common ground for interdisciplinary research and education that will be an essential component of science, engineering and technology in the future. The book is divided into three sections. Section I includes general topics related to ecotoxicity of nanomaterials to microbes, plants, human and environment. Section 2 incorporates risks generated by the use of nanomaterials. Section 3 discusss safety issues and the public.
Author: Harun Parlar
Publisher: Wiley-VCH
ISBN: 9783527319596
Category : Science
Languages : en
Pages : 208
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Book Description
This volume provides detailed, ready-to-use protocols for air monitoring methods, developed to monitor concentrations of occupational toxicants at the workplace, while they can also be used for environmental monitoring. All the methods are reliable, reproducible, adhere to quality assurance standards and cover all the required steps from sampling to the interpretation of results. This includes data on precision, accuracy, and detection limit, calibration procedures as well as potential sources of systematic errors. In addition, the advantages and disadvantages of each method are clearly outlined.
