The Liquid Scintillation Counting of Tritium and C14-labeled Compounds PDF Download
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Author: Donald J. Rosenthal
Publisher:
ISBN:
Category : Beta rays
Languages : en
Pages : 20
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Author: Donald J. Rosenthal
Publisher:
ISBN:
Category : Beta rays
Languages : en
Pages : 20
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Author: Yutaka Kobayashi
Publisher: Elsevier
ISBN: 0323160220
Category : Science
Languages : en
Pages : 207
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Book Description
Biological Applications of Liquid Scintillation Counting, based on a series of lectures given at the Worcester Foundation for Experimental Biology, discusses the various biological applications of liquid scintillation counting and presents its principles in a manner that is simple, practical, and useful. This book explains the fundamentals of scintillators and the scintillation process, from sample preparation to testing and setting up a counter and the application of radiotracers. This text is organized into six chapters and begins with a historical overview of liquid scintillation counting, emphasizing two major events that stimulated its development: the discovery of organic compounds called ""scintillators"" and the introduction of photomultiplier tubes. This book considers the factors that affect the performance of photomultiplier tubes, including temperature and magnetic fields, and the use of liquid scintillation counting to measure radioactivity. The discussion then shifts to the factors that must be taken into account when choosing a method for preparing samples, including the physical and chemical characteristics of the sample, the isotope or isotopes of the sample, and the anticipated level of radioactivity. The following chapters look at the general considerations when installing a liquid scintillation counter, procedures for applying radiotracers, and practical aspects of sample preparation. This book is intended for physicists and experimental biologists.
Author: Donald Horrocks
Publisher: Elsevier
ISBN: 0323154131
Category : Science
Languages : en
Pages : 363
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Applications of Liquid Scintillation Counting deals with liquid scintillation counting and its applications in fields such as the biosciences, medicine, environmental and space sciences, chemistry, and physics. These applications include dual-labeled counting; Cerenkov counting; radioimmunoassay, chemiluminescence and bioluminescence; pulse shape discrimination; flow cell counting; and large-volume counters. This book is comprised of 18 chapters and begins with a historical overview of the liquid scintillation method, the first liquid scintillation counters, and early scintillator solutes. The following chapters focus on the theory of liquid scintillation counting; the components of the liquid scintillator solution; and the development of the liquid scintillation counter and multiplier phototubes. The discussion then turns to the detection and measurement of different types of particles produced by radionuclides using liquid scintillation techniques; the techniques and problems of sample preparations (homogeneous and heterogeneous); oxidation techniques; and importance and difference of several types of counting vials. The sources of quenching in counting samples and methods of monitoring and correction for variable quench within samples are also considered. Several special applications of liquid scintillation techniques are presented, including dual-labeled counting, radioimmunoassay, and flow cell counting. In conclusion, the statistical considerations involved in determining the reliability and accuracy of data obtained by nuclear counting techniques are highlighted. This monograph will serve as a reliable source of information for those who are already using or starting to use liquid scintillation counting techniques.
Author: Rolf Voges
Publisher: John Wiley & Sons
ISBN: 9780470743430
Category : Science
Languages : en
Pages : 682
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Book Description
Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.
Author: United States. Superintendent of Documents
Publisher:
ISBN:
Category : United States
Languages : en
Pages : 1366
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Author:
Publisher:
ISBN:
Category : Isotopes
Languages : en
Pages : 898
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Author:
Publisher:
ISBN:
Category : Nuclear energy
Languages : en
Pages : 744
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Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages :
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Author:
Publisher:
ISBN:
Category : Nuclear engineering
Languages : en
Pages : 750
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Author:
Publisher:
ISBN:
Category : Energy development
Languages : en
Pages : 274
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