This Won't Hurt a Bit

This Won't Hurt a Bit PDF Author: Michelle Au
Publisher: Grand Central Publishing
ISBN: 0446574414
Category : Biography & Autobiography
Languages : en
Pages : 180

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Book Description
If Atul Gawande were funny--or Jerome Groopman were a working mother--they might sound something like Michelle Au, M.D., author of this hilarious and poignant memoir of a medical residency. Michelle Au started medical school armed only with a surfeit of idealism, a handful of old ER episodes for reference, and some vague notion about "helping people." This Won't Hurt a Bit is the story of how she grew up and became a real doctor. It's a no-holds-barred account of what a modern medical education feels like, from the grim to the ridiculous, from the heartwarming to the obscene. Unlike most medical memoirs, however, this one details the author's struggles to maintain a life outside of the hospital, in the small amount of free time she had to live it. And, after she and her husband have a baby early in both their medical residencies, Au explores the demands of being a parent with those of a physician, two all-consuming jobs in which the lives of others are very literally in her hands. Au's stories range from hilarious to heartbreaking and hit every note in between, proving more than anything that the creation of a new doctor (and a new parent) is far messier, far more uncertain, and far more gratifying than one could ever expect.

This Won't Hurt a Bit

This Won't Hurt a Bit PDF Author: Michelle Au
Publisher: Grand Central Publishing
ISBN: 0446574414
Category : Biography & Autobiography
Languages : en
Pages : 180

Get Book

Book Description
If Atul Gawande were funny--or Jerome Groopman were a working mother--they might sound something like Michelle Au, M.D., author of this hilarious and poignant memoir of a medical residency. Michelle Au started medical school armed only with a surfeit of idealism, a handful of old ER episodes for reference, and some vague notion about "helping people." This Won't Hurt a Bit is the story of how she grew up and became a real doctor. It's a no-holds-barred account of what a modern medical education feels like, from the grim to the ridiculous, from the heartwarming to the obscene. Unlike most medical memoirs, however, this one details the author's struggles to maintain a life outside of the hospital, in the small amount of free time she had to live it. And, after she and her husband have a baby early in both their medical residencies, Au explores the demands of being a parent with those of a physician, two all-consuming jobs in which the lives of others are very literally in her hands. Au's stories range from hilarious to heartbreaking and hit every note in between, proving more than anything that the creation of a new doctor (and a new parent) is far messier, far more uncertain, and far more gratifying than one could ever expect.

The Healing of America

The Healing of America PDF Author: T. R. Reid
Publisher: Penguin
ISBN: 0143118218
Category : Health & Fitness
Languages : en
Pages : 306

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Book Description
A New York Times Bestseller, with an updated explanation of the 2010 Health Reform Bill "Important and powerful . . . a rich tour of health care around the world." —Nicholas Kristof, The New York Times Bringing to bear his talent for explaining complex issues in a clear, engaging way, New York Times bestselling author T. R. Reid visits industrialized democracies around the world--France, Britain, Germany, Japan, and beyond--to provide a revelatory tour of successful, affordable universal health care systems. Now updated with new statistics and a plain-English explanation of the 2010 health care reform bill, The Healing of America is required reading for all those hoping to understand the state of health care in our country, and around the world. T. R. Reid's latest book, A Fine Mess: A Global Quest for a Simpler, Fairer, and More Efficient Tax System, is also available from Penguin Press.

Homocysteine in Health and Disease

Homocysteine in Health and Disease PDF Author: Ralph Carmel
Publisher: Cambridge University Press
ISBN: 9780521653190
Category : Medical
Languages : en
Pages : 558

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Book Description
This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.

Splendid Solution

Splendid Solution PDF Author: Jeffrey Kluger
Publisher: National Geographic Books
ISBN: 0425205703
Category : Medical
Languages : en
Pages : 0

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Book Description
The compelling true story of Dr. Jonas Salk's quest to develop a vaccine for polio. In 1916, the United States was hit with one of the worst polio epidemics in history. The disease was a terrifying enigma: striking out of nowhere, it afflicted tens of thousands of children and left them—literally overnight—paralyzed. Others it simply killed. At the same time, a child named Jonas Salk was born.... When Franklin Delano Roosevelt was diagnosed with polio shortly before assuming the Presidency, Salk was given an impetus to study this deadly illness. After assisting in the creation of an influenza vaccine, Salk took up the challenge. His progress in combating the virus was hindered by the politics of medicine and by a rival researcher determined to discredit his proposed solution. But Salk's perseverance made history—and for close to seventy years his vaccine has saved countless lives, bringing humanity close to eradicating polio throughout the world. Splendid Solution chronicles Dr. Salk's race against time to achieve an unparalleled breakthrough that made him a cultural hero and icon of modern medicine.

Sharing Clinical Trial Data

Sharing Clinical Trial Data PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309316324
Category : Medical
Languages : en
Pages : 304

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Book Description
Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research--from funders, to researchers, to journals, to physicians, and ultimately, to patients.

Overdiagnosed

Overdiagnosed PDF Author: H. Gilbert Welch
Publisher: Beacon Press
ISBN: 0807021997
Category : Medical
Languages : en
Pages : 249

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Book Description
An exposé on Big Pharma and the American healthcare system’s zeal for excessive medical testing, from a nationally recognized expert More screening doesn’t lead to better health—but can turn healthy people into patients. Going against the conventional wisdom reinforced by the medical establishment and Big Pharma that more screening is the best preventative medicine, Dr. Gilbert Welch builds a compelling counterargument that what we need are fewer, not more, diagnoses. Documenting the excesses of American medical practice that labels far too many of us as sick, Welch examines the social, ethical, and economic ramifications of a health-care system that unnecessarily diagnoses and treats patients, most of whom will not benefit from treatment, might be harmed by it, and would arguably be better off without screening. Drawing on 25 years of medical practice and research on the effects of medical testing, Welch explains in a straightforward, jargon-free style how the cutoffs for treating a person with “abnormal” test results have been drastically lowered just when technological advances have allowed us to see more and more “abnormalities,” many of which will pose fewer health complications than the procedures that ostensibly cure them. Citing studies that show that 10% of 2,000 healthy people were found to have had silent strokes, and that well over half of men over age sixty have traces of prostate cancer but no impairment, Welch reveals overdiagnosis to be rampant for numerous conditions and diseases, including diabetes, high cholesterol, osteoporosis, gallstones, abdominal aortic aneuryisms, blood clots, as well as skin, prostate, breast, and lung cancers. With genetic and prenatal screening now common, patients are being diagnosed not with disease but with “pre-disease” or for being at “high risk” of developing disease. Revealing the economic and medical forces that contribute to overdiagnosis, Welch makes a reasoned call for change that would save us from countless unneeded surgeries, excessive worry, and exorbitant costs, all while maintaining a balanced view of both the potential benefits and harms of diagnosis. Drawing on data, clinical studies, and anecdotes from his own practice, Welch builds a solid, accessible case against the belief that more screening always improves health care.

Statistics Applied to Clinical Trials

Statistics Applied to Clinical Trials PDF Author: Ton J. Cleophas
Publisher: Springer Science & Business Media
ISBN: 1402095236
Category : Mathematics
Languages : en
Pages : 550

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Book Description
In clinical medicine appropriate statistics has become indispensable to evaluate treatment effects. Randomized controlled trials are currently the only trials that truly provide evidence-based medicine. Evidence based medicine has become crucial to optimal treatment of patients. We can define randomized controlled trials by using Christopher J. Bulpitt’s definition “a carefully and ethically designed experiment which includes the provision of adequate and appropriate controls by a process of randomization, so that precisely framed questions can be answered”. The answers given by randomized controlled trials constitute at present the way how patients should be clinically managed. In the setup of such randomized trial one of the most important issues is the statistical basis. The randomized trial will never work when the statistical grounds and analyses have not been clearly defined beforehand. All endpoints should be clearly defined in order to perform appropriate power calculations. Based on these power calculations the exact number of available patients can be calculated in order to have a sufficient quantity of individuals to have the predefined questions answered. Therefore, every clinical physician should be capable to understand the statistical basis of well performed clinical trials. It is therefore a great pleasure that Drs. T. J. Cleophas, A. H. Zwinderman, and T. F. Cleophas have published a book on statistical analysis of clinical trials. The book entitled “Statistics Applied to Clinical Trials” is clearly written and makes complex issues in statistical analysis transparant.

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research PDF Author: John I. Gallin
Publisher: Elsevier
ISBN: 9780080489568
Category : Medical
Languages : en
Pages : 448

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Book Description
The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government

The Journal of Clinical Investigation

The Journal of Clinical Investigation PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1196

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Book Description


French's Index of Differential Diagnosis An A-Z 1

French's Index of Differential Diagnosis An A-Z 1 PDF Author: Mark T. Kinirons
Publisher: CRC Press
ISBN: 0429585853
Category : Medical
Languages : en
Pages : 1608

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Book Description
First published in 1912, French's Index of Differential Diagnosis helps clinicians in the differential diagnosis of any condition which may be seen in hospital or general practice. Arranged alphabetically by symptom, the text helps readers identify each presentation, describes the different diagnoses that it could represent, and explains the tests