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Author: Ponnusamy Rajeswaran
Publisher:
ISBN:
Category : Tranquilizing drugs
Languages : en
Pages : 272
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Book Description
Author: Ponnusamy Rajeswaran
Publisher:
ISBN:
Category : Tranquilizing drugs
Languages : en
Pages : 272
Get Book Here
Book Description
Author: Li Di
Publisher: Elsevier
ISBN: 0080557619
Category : Science
Languages : en
Pages : 549
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Book Description
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint
Author: Andrew G. Mtewa
Publisher: John Wiley & Sons
ISBN: 1119650232
Category : Science
Languages : en
Pages : 444
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Book Description
Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career
Author: Patrick Sullivan
Publisher: Elsevier
ISBN: 008045772X
Category : Technology & Engineering
Languages : en
Pages : 383
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Book Description
In today's chemically dependent society, environmental studies demonstrate that drinking water in developed countries contains numerous industrial chemicals, pesticides, pharmaceuticals and chemicals from water treatment processes. This poses a real threat. As a result of the ever-expanding list of chemical and biochemical products industry, current drinking water standards that serve to preserve our drinking water quality are grossly out of date. Environmental Science of Drinking Water demonstrates why we need to make a fundamental change in our approach toward protecting our drinking water. Factual and circumstantial evidence showing the failure of current drinking water standards to adequately protect human health is presented along with analysis of the extent of pollution in our water resources and drinking water. The authors also present detail of the currently available state-of-the-art technologies which, if fully employed, can move us toward a healthier future.* Addresses the international problems of outdated standards and the overwhelming onslaught of new contaminants. * Includes new monitoring data on non-regulated chemicals in water sources and drinking water.* Includes a summary of different bottled waters as well as consumer water purification technologies.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547693
Category : Medical
Languages : en
Pages : 80
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Book Description
This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalized anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.
Author: William W. Muir III
Publisher: Elsevier Health Sciences
ISBN: 1437710522
Category : Medical
Languages : en
Pages : 497
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Book Description
All veterinary team members involved in the everyday care of horses that require anesthesia or special emergency care will benefit from this reliable and inclusive resource. This text provides all of the information needed to prepare, conduct, and monitor the administration of drugs in order to produce safe and effective anesthesia, treat pain, respond to adverse effects, and perform and monitor emergency and critical care treatment. It is the most comprehensive and detailed book available on these subjects, addressing the needs and concerns of practitioners in both hospital and field settings. Discusses all aspects of equine anesthesia, including history, physiology, pharmacology, drug dosages, patient preparation, induction-maintenance-recovery of anesthesia management of potential complications, and more. Provides a detailed review of the respiratory and cardiovascular physiology of the horse. Provides thorough coverage of preoperative pain management in horses. Covers emergency medical care and managing anesthetic complications in both hospital and field situations. Includes information on the latest anesthetic drugs, including safe and effective protocols for different procedures, and the most up-to-date monitoring techniques. Each contributor is a recognized expert in his or her respective equine specialty, renowned for clinical as well as academic and research expertise. A complete update of all drug information and pain management techniques. The very latest research findings and clinical applications of anesthetic agents and techniques. The most recent developments in post-anesthetic care and monitoring. A chapter on intravenous anesthetic and analgesic adjuncts to inhalation anesthesia. A chapter on anesthesia and analgesia for donkeys and mules. A chapter on perioperative pain management. Many new illustrations as well as tables, graphs, boxes, key points, and summaries that make information instantly accessible.
Author: Rae Armantrout
Publisher: Wesleyan University Press
ISBN: 0819570915
Category : Poetry
Languages : en
Pages : 136
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Book Description
"A collection of poetry organized in two sections. The first section, "Versed," play with vice and versa, the perversity of human consciousness. They flirt with error and delusion, skating on a thin ice that inevitably cracks. The second section, "Dark Matter," alludes to more than the unseen substance thought to make up the majority of mass in the universe. The invisible and unknowable are confronted directly as the author's experience with cancer marks these poems with a new austerity, shot through with her signature wit and stark unsentimental thinking."--Résumé de l'éditeur.
Author: Alexandros Stefanakis
Publisher: Newnes
ISBN: 0124046878
Category : Technology & Engineering
Languages : en
Pages : 395
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Book Description
Vertical flow constructed wetlands for wastewater and sludge treatment represent a relatively new and still growing technology. Vertical Flow Constructed Wetlands is the first book to present the state-of-the-art knowledge regarding vertical flow constructed wetlands theory and applications. In this book, you will learn about vertical flow systems with information about application and performance. Vertical Flow Constructed Wetlands also includes information on how different countries are applying the technology, with design guidelines to illustrate best practices worldwide. A focus on water conservation through reuse of treated water showcases the benefit of vertical flow construction, which has greatly increased the attractiveness of the technology in recent years. - All state-of-the-art knowledge regarding vertical flow constructed wetlands gathered in one book - A review of various constructed wetland approaches, including information about applications and performance, helps clarify what is currently known about constructed wetland principles and design - Discussion of how to manage the treated wastewater leaving the vertical flow for increasing biodiversity, providing food and habitat for birds, and producing harvestable biomass or crops - Includes case studies of constructed wetlands in developing countries
Author: Satinder Ahuja
Publisher: Academic Press
ISBN: 0080921124
Category : Science
Languages : en
Pages : 457
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Book Description
This work provides those involved in water purification research and administration with a comprehensive resource of methods for analyzing water to assure its safety from contaminants, both natural and human caused. The book first provides an overview of major water-related issues in developing and developed countries, followed by a review of issues of sampling for water analysis, regulatory considerations and forensics in water quality and purity investigations. The subsequent chapters cover microbial as well chemical contaminations from inorganic compounds, radionuclides, volatile and semi-volatile compounds, disinfectants, herbicides, and pharmaceuticals, including endocrine disruptors, as well as potential terrorist-related contamination. The last chapter describes the Grainger prize-winning filter that can remove arsenic from water sources and sufficiently protect the health of a large number of people. - Covers the scope of water contamination problems on a worldwide scale - Provides a rich source of methods for analyzing water to assure its safety from natural and deliberate contaminants - Describes the filter that won the $1 million Grainger prize and thereby highlighting an important approach to remediation
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
