The Evolution of Vertebrate Blood Clotting PDF Download
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Author: Russell F. Doolittle
Publisher: University Science Books
ISBN: 9781891389818
Category : Science
Languages : en
Pages : 0
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Book Description
llluminated by a great assortment of original illustrations, this remarkable book charts the step-by-step evolution of vertebrate blood coagulation. Intended for readers with a background in biological science, it is specifically targeted for those in the field of molecular evolution as well as for researchers in the area of blood clotting. After providing some general background in the areas of blood clotting, protein structure, animal systematics, and simple genomics, the book focusses in on the search for blood clotting genes in the genomes of non-mammalian vertebrates, including fish, amphibians, reptiles and birds. The inventory of genes found allows a reconstruction of events culminating in the complex clotting system observed in humans and other mammals. Also examined are the genomes of protochordates like the sea squirt, leading to conjecture about how blood clotting was first initiated. The orderly way in which gene duplications provided new genes for fine-tuning the system serves as a model for how complex physiological systems in general have evolved. The book ends with suggestions for specific genetic engineering experiments that can be done to illustrate how molecular evolution works. An extensive glossary and guide to the current literature combine to make this book ideal for course use as well as for self study.
Author: Russell F. Doolittle
Publisher: University Science Books
ISBN: 9781891389818
Category : Science
Languages : en
Pages : 0
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Book Description
llluminated by a great assortment of original illustrations, this remarkable book charts the step-by-step evolution of vertebrate blood coagulation. Intended for readers with a background in biological science, it is specifically targeted for those in the field of molecular evolution as well as for researchers in the area of blood clotting. After providing some general background in the areas of blood clotting, protein structure, animal systematics, and simple genomics, the book focusses in on the search for blood clotting genes in the genomes of non-mammalian vertebrates, including fish, amphibians, reptiles and birds. The inventory of genes found allows a reconstruction of events culminating in the complex clotting system observed in humans and other mammals. Also examined are the genomes of protochordates like the sea squirt, leading to conjecture about how blood clotting was first initiated. The orderly way in which gene duplications provided new genes for fine-tuning the system serves as a model for how complex physiological systems in general have evolved. The book ends with suggestions for specific genetic engineering experiments that can be done to illustrate how molecular evolution works. An extensive glossary and guide to the current literature combine to make this book ideal for course use as well as for self study.
Author: Julianne Zedalis
Publisher:
ISBN: 9781947172401
Category : Biology
Languages : en
Pages : 1923
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Book Description
Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Author: Michael J. Behe
Publisher: Simon and Schuster
ISBN: 0743296222
Category : Religion
Languages : en
Pages : 339
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Book Description
The author of Darwin's Black Box draws on new findings in genetics to pose an argument for intelligent design that refutes Darwinian beliefs about evolution while offering alternative analyses of such factors as disease, random mutations, and the human struggle for survival. Reprint. 40,000 first printing.
Author: Torben Halkier
Publisher: Cambridge University Press
ISBN: 9780521381871
Category : Medical
Languages : en
Pages : 488
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Book Description
This book provides a comprehensive account of the proteins involved in blood coagulation, fibrinolysis and the complement system. A major section of the book is devoted to each of these three systems, with separate chapters dealing in detail with structural aspects and different functional processes. Topics covered in the blood coagulation section include the activation of factors IX and X and prothrombin, and the formation and stabilisation of fibrin. The fibrinolysis section includes the activation of plasminogen, the degradation of fibrin and the regulation of fibrinolysis. The complement system itself is covered in chapters dealing with classical activation, alternative activation, the lytic complex and the regulatory processes involved. In addition, one section deals with special topics, including the kinin system, signal peptides, haemostasis, and the evolution of protein structure. This volume will be of use to researchers and advanced students in the fields of haematology, immunology and clinical chemistry.
Author: Ronny C. Woodruff
Publisher: Springer Science & Business Media
ISBN: 9401152101
Category : Science
Languages : en
Pages : 561
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Book Description
Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-to-date reviews, the authors provide an insightful overview of each topic and then share their newest ideas and explore controversial aspects of mutation and the evolutionary process. From topics like gonadal mosaicism and mutation clusters to adaptive mutagenesis, mutation in cell organelles, and the level and distribution of DNA molecular changes, the foundation is set for continuing the debate about the role of mutation, fitness, and adaptability. It is a debate that will have profound consequences for our understanding of evolution.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Robert F. Shedinger
Publisher: Wipf and Stock Publishers
ISBN: 1532658338
Category : Science
Languages : en
Pages : 303
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Book Description
Is Darwinian evolution really the most successful scientific theory ever proposed—or even the best idea anyone has ever had, as Daniel Dennett once put it? The Mystery of Evolutionary Mechanisms provides a comprehensive critical reading of the literature of evolutionary biology from Darwin to Dobzhansky to Dawkins, revealing this popular account of evolution to be a grand narrative of Darwinian triumph that greatly overstates the empirical validity of modern evolutionary theory. The mechanisms driving the evolutionary process truly remain a mystery more than one hundred fifty years after Origin of Species, a fact that can free religion scholars to think in more creative ways about the positive contributions religious reflection might make to our understanding of life’s origin and diversity. The Mystery of Evolutionary Mechanisms calls for an embrace of mystery, understood not as an abdication of the scientific quest for truth but as a courageous and humble acknowledgment of the limits of human reason and an openness to a fundamentally religious orientation toward life.
Author: Mike Lehane
Publisher: Springer Science & Business Media
ISBN: 9401179530
Category : Science
Languages : en
Pages : 301
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Book Description
Blood-sucking insects are the vectors of many of the most debilitating parasites of man and his domesticated animals. In addition they are of considerable direct cost to the agricultural industry through losses in milk and meat yields, and through damage to hides and wool, etc. So, not surprisingly, many books of medical and veterinary entomology have been written. Most of these texts are organized taxonomically giving the details of the life-cycles, bionomics, relationship to disease and economic importance of each of the insect groups in turn. I have taken a different approach. This book is topic led and aims to discuss the biological themes which are common in the lives of blood-sucking insects. To do this I have concentrated on those aspects of the biology of these fascinating insects which have been clearly modified in some way to suit the blood-sucking habit. For example, I have discussed feeding and digestion in some detail because feeding on blood presents insects with special problems, but I have not discussed respiration because it is not affected in any particular way by haematophagy. Naturally there is a subjective element in the choice of topics for discussion and the weight given to each. I hope that I have not let my enthusiasm for particular subjects get the better of me on too many occasions and that the subject material achieves an overall balance.
Author: Kenneth R. Miller
Publisher: Harper Perennial
ISBN: 9780061233500
Category : Science
Languages : en
Pages : 368
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Book Description
From a leading authority on the evolution debates comes this critically acclaimed investigation into one of the most controversial topics of our times
Author: Francisco J. Ayala
Publisher: Academic Press
ISBN: 0128037318
Category : Science
Languages : en
Pages : 424
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Book Description
Evolution, Explanation, Ethics and Aesthetics: Towards a Philosophy of Biology focuses on the dominant biological topic of evolution. It deals with the prevailing philosophical themes of how to explain the adaptation of organisms, the interplay of chance and necessity, and the recurrent topics of emergence, reductionism, and progress. In addition, the extensively treated topic of how to explain human nature as a result of natural processes and the encompassed issues of the foundations of morality and the brain-to-mind transformation is discussed. The philosophy of biology is a rapidly expanding field, not more than half a century old at most, and to a large extent is replacing the interest in the philosophy of physics that prevailed in the first two-thirds of the twentieth century. Few texts available have the benefit of being written by an eminent biologist who happens to be also a philosopher, as in this work. This book is a useful resource for seminar courses and college courses on the philosophy of biology. Researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity will also be interested in this work, as will those in human biology and issues such as ethics, religion, and the human mind, along with professional philosophers of science and those concerned with such issues as whether evolution is compatible with religion and/or where morality comes from. - Presents the unique perspective of a distinguished biologist with extensive experience in the field who has published much about the subject in a wide variety of journals and edited volumes - Covers the philosophical issues related to evolution and biology in an approachable and readable style - Includes the most up-to-date treatment of this burgeoning, exciting field within biology - Provides the ideal guide for researchers, academics, and students in evolutionary biology, behavior, genetics, and biodiversity
