The Enantioselective Synthesis of 3-polyenoyltetramic Acids PDF Download
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Author: Brodyck James Lachlan Royles
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages : 0
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Book Description
Abstract: The total synthesis of the 3-polyenoyltetramic acid antibiotic altamycin A has been attempted via a novel method of preparing enantiometrically pure tetramic acids. ...
Author: Brodyck James Lachlan Royles
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages : 0
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Book Description
Abstract: The total synthesis of the 3-polyenoyltetramic acid antibiotic altamycin A has been attempted via a novel method of preparing enantiometrically pure tetramic acids. ...
Author: Brodyck James Lachlan Royles
Publisher:
ISBN:
Category : Antibiotics
Languages : en
Pages :
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Book Description
Abstract: The total synthesis of the 3-polyenoyltetramic acid antibiotic altamycin A has been attempted via a novel method of preparing enantiometrically pure tetramic acids. ...
Author: Eusebio Juaristi
Publisher: Wiley-VCH
ISBN: 0471698474
Category : Science
Languages : en
Pages : 600
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Book Description
Covers all facets of the synthesis of ?-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ?-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ?-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ?-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ?-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ?-amino acid targets and salient ?-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ?-amino acids * Includes general and practical procedures for the preparation of ?-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ?-amino acids * Includes a report on the preparation of libraries of enantiopure ?-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ?-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.
Author: James Guy Breitenbucher
Publisher:
ISBN:
Category : Amino acids
Languages : en
Pages : 358
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Book Description
Author: Erick M. Carreira
Publisher: John Wiley & Sons
ISBN: 9783527324521
Category : Science
Languages : en
Pages : 664
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Book Description
Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.
Author: Elias J. Corey
Publisher: Elsevier
ISBN: 0128001518
Category : Science
Languages : en
Pages : 334
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Book Description
Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field's progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. - In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. - Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. - Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules - Clearly explains stereochemical synthesis in theory and practice - Provides a handy tool box for scientists wishing to understand and apply chiral chemical synthesis - Describes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages
Author: Maria Elizabeth Tiritan
Publisher: MDPI
ISBN: 3039362380
Category : Technology & Engineering
Languages : en
Pages : 346
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Book Description
This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities.
Author: Eusebio Juaristi
Publisher: Wiley
ISBN: 9780471186274
Category : Science
Languages : en
Pages : 0
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Book Description
This book presents an overview of the importance of ß-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing ß-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including ß-lacatams.
Author: Otakar Červinka
Publisher:
ISBN:
Category : Optical isomers
Languages : en
Pages : 212
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Book Description
Author: Hélène Pellissier
Publisher: John Wiley & Sons
ISBN: 3527341145
Category : Science
Languages : en
Pages : 606
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Book Description
The first handbook to focus on the asymmetric synthesis of different types of three-membered rings. The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings. With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.
