Fundamentals of Biomechanics

Fundamentals of Biomechanics PDF Author: Duane Knudson
Publisher: Springer Science & Business Media
ISBN: 1475752989
Category : Medical
Languages : en
Pages : 332

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Book Description
Fundamentals of Biomechanics introduces the exciting world of how human movement is created and how it can be improved. Teachers, coaches and physical therapists all use biomechanics to help people improve movement and decrease the risk of injury. The book presents a comprehensive review of the major concepts of biomechanics and summarizes them in nine principles of biomechanics. Fundamentals of Biomechanics concludes by showing how these principles can be used by movement professionals to improve human movement. Specific case studies are presented in physical education, coaching, strength and conditioning, and sports medicine.

Fundamentals of Biomechanics

Fundamentals of Biomechanics PDF Author: Duane Knudson
Publisher: Springer Science & Business Media
ISBN: 1475752989
Category : Medical
Languages : en
Pages : 332

Get Book Here

Book Description
Fundamentals of Biomechanics introduces the exciting world of how human movement is created and how it can be improved. Teachers, coaches and physical therapists all use biomechanics to help people improve movement and decrease the risk of injury. The book presents a comprehensive review of the major concepts of biomechanics and summarizes them in nine principles of biomechanics. Fundamentals of Biomechanics concludes by showing how these principles can be used by movement professionals to improve human movement. Specific case studies are presented in physical education, coaching, strength and conditioning, and sports medicine.

Transgenic Models in Pharmacology

Transgenic Models in Pharmacology PDF Author: Lutz Hein
Publisher: Springer Science & Business Media
ISBN: 9783540001096
Category : Medical
Languages : en
Pages : 692

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Book Description
Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.

The Extracellular Matrix: an Overview

The Extracellular Matrix: an Overview PDF Author: Robert Mecham
Publisher: Springer Science & Business Media
ISBN: 3642165559
Category : Science
Languages : en
Pages : 429

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Book Description
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Signaling and the Cytoskeleton

Signaling and the Cytoskeleton PDF Author: Kermit L. Carraway
Publisher: Springer Science & Business Media
ISBN: 3662129930
Category : Science
Languages : en
Pages : 293

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Book Description
This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

Gene Therapy

Gene Therapy PDF Author: Mauro Giacca
Publisher: Springer Science & Business Media
ISBN: 8847016436
Category : Medical
Languages : en
Pages : 318

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Book Description
I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.

Industrial Pharmaceutical Biotechnology

Industrial Pharmaceutical Biotechnology PDF Author: Heinrich Klefenz
Publisher: Wiley-VCH
ISBN:
Category : Medical
Languages : de
Pages : 328

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Book Description
This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Histone Deacetylases: the Biology and Clinical Implication

Histone Deacetylases: the Biology and Clinical Implication PDF Author: Tso-Pang Yao
Publisher: Springer Science & Business Media
ISBN: 3642216315
Category : Medical
Languages : en
Pages : 269

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Book Description
The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune dysfunctions, heart disease, cancer, memory impairment, aging, and metabolic disorders.

Biomechanics of Feeding in Vertebrates

Biomechanics of Feeding in Vertebrates PDF Author: V.L. Bels
Publisher: Springer Science & Business Media
ISBN: 364257906X
Category : Science
Languages : en
Pages : 372

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Book Description
Although feeding is not yet been thoroughly studied in many vertebrates taxa, and different conceptual and methodological approaches of the concerned scientists make a synthesis difficult, the aim of the editors is to provide a comprehensive overview of the feeding design in aquatic and terrestrial vertebrates with a detailed description of its functional properties. The book emphasizes the constant interaction between function and form, behaviour and morphology in the course of evolution of the feeding apparatus and way of feeding both complementary and basically related to survival interspecific competition, adaptation to environmental changes and adaptive radiations. Special stress is drawn onquantification of the observational and experimental data on the morphology and biomechanics of the feeding design and its element jaws, teeth, hyoidean apparatus, tongue, in order to allow present and further comparisons in an evolutionary perspective.

Stem Cell Engineering

Stem Cell Engineering PDF Author: Gerhard M. Artmann
Publisher: Springer Science & Business Media
ISBN: 3642118658
Category : Technology & Engineering
Languages : en
Pages : 566

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Book Description
The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.

Practical Methods in Cardiovascular Research

Practical Methods in Cardiovascular Research PDF Author: Stefan Dhein
Publisher: Springer
ISBN: 3540265740
Category : Medical
Languages : en
Pages : 1011

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Book Description
Scientists working or planning to work in the field of cardiovascular research will welcome Methods in Cardiovascular Research as the reference book they have been waiting for. Not only general aspects of cardiovascular research are well presented but also detailed descriptions of methods, protocols and practical examples. Written by leading scientists in their field, chapters cover classical methods such as the Langendorff heart or working heart models as well as numerous new techniques and methods. Newcomers and experienced researchers alike will benefit from the troubleshooting guide in each chapter, the extensive reference lists for advanced reading and the great practical experience of the authors. Methods in Cardiovascular Research is a "must have" for anybody with an interest in cardiovascular research.