Author:
Publisher:
ISBN:
Category : Heraldry
Languages : en
Pages : 284
Book Description
The Ancestor
Author:
Publisher:
ISBN:
Category : Heraldry
Languages : en
Pages : 284
Book Description
Publisher:
ISBN:
Category : Heraldry
Languages : en
Pages : 284
Book Description
Compilation of History of the Barner Family: Family history and family trees
Author: Konrad von Barner
Publisher:
ISBN:
Category :
Languages : en
Pages : 396
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 396
Book Description
Cruel and Unusual
Author: Brian Jarvis
Publisher: Pluto Press (UK)
ISBN:
Category : History
Languages : en
Pages : 304
Book Description
Explores who -- and why -- American society punishes, using examples from literature and film.
Publisher: Pluto Press (UK)
ISBN:
Category : History
Languages : en
Pages : 304
Book Description
Explores who -- and why -- American society punishes, using examples from literature and film.
Forbidden Thirteen
Author: Erin Richards
Publisher: Midnight Muse Publishing
ISBN: 1943800081
Category : Fiction
Languages : en
Pages : 360
Book Description
Publisher: Midnight Muse Publishing
ISBN: 1943800081
Category : Fiction
Languages : en
Pages : 360
Book Description
Promiscuous Functions of the Prion Protein Gene Family
Author: Sophie Mouillet-Richard
Publisher: Frontiers Media SA
ISBN: 2889196054
Category : Biology (General)
Languages : en
Pages : 115
Book Description
The cellular prion protein PrPC is a ubiquitous GPI-anchored protein. While PrPC has been the focus of intense research for its involvement in a group of neurodegenerative disorders known as transmissible spongiform encephalopathies (TSE), much less attention has been devoted to its physiological function. This notably relates to the lack of obvious abnormalities of mice, goat or cattle lacking PrPC. This apparently normal phenotype in these PrPC-deficient animals however contrasts with the very high degree of conservation of the prion protein gene (Prnp) in mammalian species (over 80%), and the presence of genes with similarities to Prnp in birds, reptiles, amphibians and fish. This high conservation together with its ubiquitous expression, - albeit at highest levels in the brain-, suggest that PrPC has major physiological functions. Dissecting PrPC function is further complicated by the occurrence, in mammals, of two potentially partially redundant homologues, Doppel, and Shadoo. The biological overlaps between members of the prion protein family are still under investigation and much debated. Similarly, although in vitro analyses have suggested various functions for PrPC, notably in cell death and survival processes, some have yielded conflicting results and/or discrepancies with in vivo studies. This Research Topic brings together the accumulated knowledge regarding the biological roles of the prion protein family, from the animal to the molecular scale.
Publisher: Frontiers Media SA
ISBN: 2889196054
Category : Biology (General)
Languages : en
Pages : 115
Book Description
The cellular prion protein PrPC is a ubiquitous GPI-anchored protein. While PrPC has been the focus of intense research for its involvement in a group of neurodegenerative disorders known as transmissible spongiform encephalopathies (TSE), much less attention has been devoted to its physiological function. This notably relates to the lack of obvious abnormalities of mice, goat or cattle lacking PrPC. This apparently normal phenotype in these PrPC-deficient animals however contrasts with the very high degree of conservation of the prion protein gene (Prnp) in mammalian species (over 80%), and the presence of genes with similarities to Prnp in birds, reptiles, amphibians and fish. This high conservation together with its ubiquitous expression, - albeit at highest levels in the brain-, suggest that PrPC has major physiological functions. Dissecting PrPC function is further complicated by the occurrence, in mammals, of two potentially partially redundant homologues, Doppel, and Shadoo. The biological overlaps between members of the prion protein family are still under investigation and much debated. Similarly, although in vitro analyses have suggested various functions for PrPC, notably in cell death and survival processes, some have yielded conflicting results and/or discrepancies with in vivo studies. This Research Topic brings together the accumulated knowledge regarding the biological roles of the prion protein family, from the animal to the molecular scale.
A Stranger at My Table
Author: Ivo de Figueiredo
Publisher: Doppelhouse Press
ISBN: 9780999754474
Category : Biography & Autobiography
Languages : en
Pages : 336
Book Description
A biracial son of a subcontinental, migrant family searches for his estranged father's story and ultimately rewrites his own.
Publisher: Doppelhouse Press
ISBN: 9780999754474
Category : Biography & Autobiography
Languages : en
Pages : 336
Book Description
A biracial son of a subcontinental, migrant family searches for his estranged father's story and ultimately rewrites his own.
Brungardt Genealogy
Author: Helen Linenberger Hall
Publisher:
ISBN:
Category :
Languages : en
Pages : 678
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 678
Book Description
Belgravia
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 686
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 686
Book Description
History of America
Author: William Robertson
Publisher:
ISBN:
Category :
Languages : en
Pages : 294
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 294
Book Description
Weigel Genealogy
Author: Amy Brungardt Toepfer
Publisher:
ISBN:
Category :
Languages : en
Pages : 652
Book Description
Dr. Thomas Weigel was born at Becherbach, Germany about 1730. He and his wife died in 1766 and were buried in Kostroma, Russia.
Publisher:
ISBN:
Category :
Languages : en
Pages : 652
Book Description
Dr. Thomas Weigel was born at Becherbach, Germany about 1730. He and his wife died in 1766 and were buried in Kostroma, Russia.