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Author: Harold Slavkin
Publisher: Academic Press
ISBN: 0323148220
Category : Science
Languages : en
Pages : 493
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Book Description
The Comparative Molecular Biology of Extracellular Matrices reviews and assesses the comparative molecular biology of extracellular matrices. It covers six areas that are advanced to supplement this study. These include the molecular biology of collagen, monopolysaccharides, proteoglycans, and structural glycoproteins; development process of extracellular matrices; cell surfaces and interactions; evolution of bone and some tissues; and biophysical properties of connective tissues.
Author: Harold Slavkin
Publisher: Academic Press
ISBN: 0323148220
Category : Science
Languages : en
Pages : 493
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Book Description
The Comparative Molecular Biology of Extracellular Matrices reviews and assesses the comparative molecular biology of extracellular matrices. It covers six areas that are advanced to supplement this study. These include the molecular biology of collagen, monopolysaccharides, proteoglycans, and structural glycoproteins; development process of extracellular matrices; cell surfaces and interactions; evolution of bone and some tissues; and biophysical properties of connective tissues.
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Category :
Languages : en
Pages :
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Languages : en
Pages : 0
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Author: Harold Slavkin
Publisher: Elsevier
ISBN: 0323142141
Category : Nature
Languages : en
Pages : 876
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Book Description
Extracellular Matrix Influences on Gene Expression emerged from the Second international Santa Catalina Island Colloquium that deals with the discussion on the advances in the molecular biology of extracellular matrices and the epigenetic influences on cell function. Topics discussed include morphological descriptions, genetics, teratology, collagen heterogeneity, and mineralization. The book's 12 chapters discuss the chromosomal and extrachromosomal influences upon transcription, translational and post-translational regulations during development, and regulation of extracellular matrix molecular biosynthesis. The book describes the regulation of tissue-specific collagen biosynthesis and the extracellular matrix macromolecules. It contains papers that explain the outer cell surface specificity and cell interactions. Because there are advances as well in other specific topics, such as the epithelial-masenchymal interactions and extracellular matrix influences on gene expression, this book contains papers that deal with these subject matters. Furthermore, it explains the matrix-cell and cell-matrix interactions and mineralization processes, as well as the aberrations in developmental processes. This book will be useful to those individuals who study the scientific advances in developmental biology.
Author: Charles Boyd
Publisher: Elsevier
ISBN: 0323157661
Category : Medical
Languages : en
Pages : 287
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Book Description
Extracellular Matrix Genes provides some of the interesting complexities of the structure of the entire family of extracellular matrix genes. This book illustrates the permanent role that molecular biology and molecular genetics play in the detailed understanding of the normal biology of extracellular matrix. Organized into 10 chapters, this book begins with an overview of the structural and sequence aspects of the entire family of genomic sequences with a view to establishing common functional domains among collagens and their genes. This text then examines the status of the literature concerning human types. III and V. Other chapters consider the FACIT collagen gene family. This book discusses as well the development in understanding the structure of small proteoglycan core proteins and their role in proteoglycan biosynthesis and function as a result of their molecular cloning and expression. The final chapter deals with mutations in collagen genes. This book is a valuable resource for biochemists.
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ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Author: W. Steven Adair
Publisher: Academic Press
ISBN: 0323153224
Category : Science
Languages : en
Pages : 381
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Book Description
Organization and Assembly of Plant and Animal Extracellular Matrix presents a state-of-the-art view of some of the experimental systems in plant and animal matrix biology. It discusses certain principles underlying establishment of complex three-dimensional architecture cross broad evolutionary boundaries. The opening chapter reviews studies on the cellular mechanisms responsible for storage, release, assembly, and function of extracellular matrices during early sea urchin development. The subsequent chapters describe the structure, assembly, disassembly, and molecular biology of the Chlamydomonas reinhardtii cell wall. The chapters also summarize the status of work on basement membrane assembly. Important insights into approaches to identify critical molecular domains and the complexity of relating defined molecular associations to establishment of matrix architecture are provided. A family of discovered cell wall genes that encode protein products containing up to 70% glycine is presented in Chapter 4. This is followed by a discussion on the role of alginate self-assembly in cell wall formation in Fucus. The book goes on to address the issue of protein-carbohydrate recognition with a detailed discussion of plant and animal lectins. Chapter 7 tackles a family of genes encoding higher plant hydroxyproline-rich glycoproteins (HRGPs) and the relationship between the HRGP genes cloned and their products. The final two chapters are devoted to one of the most important classes of protein modifying enzymes for extracellular matrix formation and function, the prolyl hydroxylases. This book will be of help to workers in plant and animal matrix in understanding information, approaches, and ideas that they may not normally encounter.
Author: Fred W. Keeley
Publisher: Springer Science & Business Media
ISBN: 3642360025
Category : Science
Languages : en
Pages : 297
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Book Description
The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
Author: Robert Mecham
Publisher: Springer Science & Business Media
ISBN: 3642165559
Category : Science
Languages : en
Pages : 429
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Book Description
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Author: Harold C. Slavkin
Publisher:
ISBN:
Category :
Languages : en
Pages : 468
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Book Description
