Author: Salvatore V. Pizzo
Publisher: Academic Press
ISBN: 0128123524
Category : Science
Languages : en
Pages : 144
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Book Description
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease Provides four-color illustrations that facilitate the narrative
Author: Carl-Henrik Heldin
Publisher: Garland Science
ISBN: 9780748740741
Category : Cell physiology
Languages : en
Pages : 404
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Book Description
Signal Transduction was published in association with The International Union of Biochemistry and Molecular Biology. In a series of twenty-three short chapters, leading researchers provide cutting-edge reviews of signal transduction, and form cell membrane receptors through to gene regulation. Written for those with a basic understanding of molecular and cell biology, the book will be of particular interest to graduate students and researchers who need to grasp the principles of signal transduction.
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: E. Wagner
Publisher: Springer
ISBN: 9783642729126
Category : Science
Languages : en
Pages : 243
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Book Description
This volume deals with the significance of the apoblast and the intracellular matrix in cell to cell signaling in plants and animals. Researchers working on human, animal and plant systems discuss their own specific problems. The dynamics of the cell surface as related to both growth and development, as well as to the transduction of environmental signals and the feed-back from genetic information to the cell surface are comprehensively covered. Special emphasis is laid on experimental models, their applicability and discussion of possible directions for future research.
Author: Bastien D. Gomperts
Publisher: Gulf Professional Publishing
ISBN: 9780122896323
Category : Medical
Languages : en
Pages : 444
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Book Description
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Author: Krishna C. Persaud
Publisher: CRC Press
ISBN: 1439871728
Category : Medical
Languages : en
Pages : 237
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Book Description
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Author: E. Wagner
Publisher:
ISBN: 9780387181981
Category :
Languages : en
Pages : 243
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Book Description
Author: ljsbrand M. Kramer
Publisher: Academic Press
ISBN: 0123948193
Category : Science
Languages : en
Pages : 1126
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Book Description
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Author: Lisa Bartee
Publisher:
ISBN: 9781636350417
Category :
Languages : en
Pages :
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Book Description
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.
Author: A.E. Evangelopoulos
Publisher: Springer Science & Business Media
ISBN: 3642742009
Category : Science
Languages : en
Pages : 398
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Book Description
A NATO Advanced study Institute on "Receptors, Membrane Trans port and Signal Transduction", was held on the Island of Spet sai, Greece, from August 16-27, 1988, in order to consider re cent developments in membrane receptor research, membrane trans port and signal transduction mechanisms. These topics were put in the larger context of current knowledge on the structure and function of membranes; connections between different fields of research were established by in-depth dis cussions of energy transduction and transport mechanisms. The general principles of regulation by signal transduction and protein phosphorylation/dephosphorylation were presented in the context of specific cellular processes. Discussions included al so the role of protein tyrosine kinases which are structurally related to oncogene products and, therefore, implicated in va rious aspects of cell development and transformation. This book presents the content of the major lectures and a se lection of the most relevant posters presented during the course of the Institute. The book is intended to make the proceedings of the Institute accessible to a larger audience and to offer a comprehensive account of those topics on receptors, membrane transport and signal transduction that were discussed extensive ly during the course of the Institute. February 1989 The Editors CONTENTS I. G-PROTEINS, ADENYLATE CYCLASE AND PROTEIN PHOSPHORYLATION Selective regulation of G proteins by Cell surface receptors ......... .