Author: Michel Morange
Publisher: Harvard University Press
ISBN: 0674281365
Category : Science
Languages : en
Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
The Black Box of Biology
Author: Michel Morange
Publisher: Harvard University Press
ISBN: 0674281365
Category : Science
Languages : en
Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Publisher: Harvard University Press
ISBN: 0674281365
Category : Science
Languages : en
Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Darwin's Black Box
Author: Michael J. Behe
Publisher: Simon and Schuster
ISBN: 9780684827544
Category : Evolution (Biology)
Languages : en
Pages : 353
Book Description
Behe argues that the complexity of cellular biochemistry argues against Darwin's gradual evolution.
Publisher: Simon and Schuster
ISBN: 9780684827544
Category : Evolution (Biology)
Languages : en
Pages : 353
Book Description
Behe argues that the complexity of cellular biochemistry argues against Darwin's gradual evolution.
A History of Molecular Biology
Author: Michel Morange
Publisher: Harvard University Press
ISBN: 9780674001695
Category : History
Languages : en
Pages : 350
Book Description
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Publisher: Harvard University Press
ISBN: 9780674001695
Category : History
Languages : en
Pages : 350
Book Description
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Black Boxes
Author: Marco J. Nathan
Publisher: Oxford University Press
ISBN: 0190095482
Category : Philosophy
Languages : en
Pages : 313
Book Description
Bricks and boxes -- Between Scylla and Charybdis -- Lessons from the history of science -- Placeholders -- Black-boxing 101 -- History of science 'black-boxing style' -- Diet mechanistic philosophy -- Emergence reframed -- The fuel of scientific progress -- Sailing through the strait.
Publisher: Oxford University Press
ISBN: 0190095482
Category : Philosophy
Languages : en
Pages : 313
Book Description
Bricks and boxes -- Between Scylla and Charybdis -- Lessons from the history of science -- Placeholders -- Black-boxing 101 -- History of science 'black-boxing style' -- Diet mechanistic philosophy -- Emergence reframed -- The fuel of scientific progress -- Sailing through the strait.
A History of Biology
Author: Michel Morange
Publisher: Princeton University Press
ISBN: 0691253927
Category : Science
Languages : en
Pages : 448
Book Description
A comprehensive history of the biological sciences from antiquity to the modern era This book presents a global history of the biological sciences from ancient times to today, providing needed perspective on the development of biological thought while shedding light on the field's upheavals and key breakthroughs through the ages. Michel Morange brings to life the dynamic interplay of science, society, and biology’s many subdisciplines, enabling readers to better appreciate the interdisciplinary exchanges that have shaped the field over the centuries. Each chapter of this incisive book focuses on a specific period in the history of biology, describing the major transformations that occurred, the enduring scientific concerns behind these changes, and the implications of yesterday's science for today's. Morange covers everything from the first cell theory to the origins of the concept of ecosystems, and offers perspectives on areas that are often neglected by historians of biology, such as ecology, ethology, and plant biology. Along the way, he highlights the contributions of technology, the important role of hypothesis and experimentation, and the cultural contexts in which some of the most breathtaking discoveries in biology were made. Unrivaled in scope and written by a world-renowned historian of science, A History of Biology is an ideal introduction for students and experts alike, and essential reading for anyone seeking to understand the present state of biological knowledge.
Publisher: Princeton University Press
ISBN: 0691253927
Category : Science
Languages : en
Pages : 448
Book Description
A comprehensive history of the biological sciences from antiquity to the modern era This book presents a global history of the biological sciences from ancient times to today, providing needed perspective on the development of biological thought while shedding light on the field's upheavals and key breakthroughs through the ages. Michel Morange brings to life the dynamic interplay of science, society, and biology’s many subdisciplines, enabling readers to better appreciate the interdisciplinary exchanges that have shaped the field over the centuries. Each chapter of this incisive book focuses on a specific period in the history of biology, describing the major transformations that occurred, the enduring scientific concerns behind these changes, and the implications of yesterday's science for today's. Morange covers everything from the first cell theory to the origins of the concept of ecosystems, and offers perspectives on areas that are often neglected by historians of biology, such as ecology, ethology, and plant biology. Along the way, he highlights the contributions of technology, the important role of hypothesis and experimentation, and the cultural contexts in which some of the most breathtaking discoveries in biology were made. Unrivaled in scope and written by a world-renowned historian of science, A History of Biology is an ideal introduction for students and experts alike, and essential reading for anyone seeking to understand the present state of biological knowledge.
Gene Sharing and Evolution
Author: Joram Piatigorsky
Publisher: Harvard University Press
ISBN: 9780674023413
Category : Science
Languages : en
Pages : 434
Book Description
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
Publisher: Harvard University Press
ISBN: 9780674023413
Category : Science
Languages : en
Pages : 434
Book Description
In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
The Black Box Society
Author: Frank Pasquale
Publisher: Harvard University Press
ISBN: 0674967100
Category : Law
Languages : en
Pages : 320
Book Description
Every day, corporations are connecting the dots about our personal behavior—silently scrutinizing clues left behind by our work habits and Internet use. The data compiled and portraits created are incredibly detailed, to the point of being invasive. But who connects the dots about what firms are doing with this information? The Black Box Society argues that we all need to be able to do so—and to set limits on how big data affects our lives. Hidden algorithms can make (or ruin) reputations, decide the destiny of entrepreneurs, or even devastate an entire economy. Shrouded in secrecy and complexity, decisions at major Silicon Valley and Wall Street firms were long assumed to be neutral and technical. But leaks, whistleblowers, and legal disputes have shed new light on automated judgment. Self-serving and reckless behavior is surprisingly common, and easy to hide in code protected by legal and real secrecy. Even after billions of dollars of fines have been levied, underfunded regulators may have only scratched the surface of this troubling behavior. Frank Pasquale exposes how powerful interests abuse secrecy for profit and explains ways to rein them in. Demanding transparency is only the first step. An intelligible society would assure that key decisions of its most important firms are fair, nondiscriminatory, and open to criticism. Silicon Valley and Wall Street need to accept as much accountability as they impose on others.
Publisher: Harvard University Press
ISBN: 0674967100
Category : Law
Languages : en
Pages : 320
Book Description
Every day, corporations are connecting the dots about our personal behavior—silently scrutinizing clues left behind by our work habits and Internet use. The data compiled and portraits created are incredibly detailed, to the point of being invasive. But who connects the dots about what firms are doing with this information? The Black Box Society argues that we all need to be able to do so—and to set limits on how big data affects our lives. Hidden algorithms can make (or ruin) reputations, decide the destiny of entrepreneurs, or even devastate an entire economy. Shrouded in secrecy and complexity, decisions at major Silicon Valley and Wall Street firms were long assumed to be neutral and technical. But leaks, whistleblowers, and legal disputes have shed new light on automated judgment. Self-serving and reckless behavior is surprisingly common, and easy to hide in code protected by legal and real secrecy. Even after billions of dollars of fines have been levied, underfunded regulators may have only scratched the surface of this troubling behavior. Frank Pasquale exposes how powerful interests abuse secrecy for profit and explains ways to rein them in. Demanding transparency is only the first step. An intelligible society would assure that key decisions of its most important firms are fair, nondiscriminatory, and open to criticism. Silicon Valley and Wall Street need to accept as much accountability as they impose on others.
Inside the black box
Author: Paul Black
Publisher: Granada Learning
ISBN: 9780708713815
Category : Education
Languages : en
Pages : 24
Book Description
Offers practical advice on using and improving assessment for learning in the classroom.
Publisher: Granada Learning
ISBN: 9780708713815
Category : Education
Languages : en
Pages : 24
Book Description
Offers practical advice on using and improving assessment for learning in the classroom.
Darwin Devolves
Author: Michael J. Behe
Publisher: HarperCollins
ISBN: 0062842684
Category : Science
Languages : en
Pages : 396
Book Description
The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator. In his controversial bestseller Darwin’s Black Box, biochemist Michael Behe challenged Darwin’s theory of evolution, arguing that science itself has proven that intelligent design is a better explanation for the origin of life. In Darwin Devolves, Behe advances his argument, presenting new research that offers a startling reconsideration of how Darwin’s mechanism works, weakening the theory’s validity even more. A system of natural selection acting on random mutation, evolution can help make something look and act differently. But evolution never creates something organically. Behe contends that Darwinism actually works by a process of devolution—damaging cells in DNA in order to create something new at the lowest biological levels. This is important, he makes clear, because it shows the Darwinian process cannot explain the creation of life itself. “A process that so easily tears down sophisticated machinery is not one which will build complex, functional systems,” he writes. In addition to disputing the methodology of Darwinism and how it conflicts with the concept of creation, Behe reveals that what makes Intelligent Design unique—and right—is that it acknowledges causation. Evolution proposes that organisms living today are descended with modification from organisms that lived in the distant past. But Intelligent Design goes a step further asking, what caused such astounding changes to take place? What is the reason or mechanism for evolution? For Behe, this is what makes Intelligent Design so important.
Publisher: HarperCollins
ISBN: 0062842684
Category : Science
Languages : en
Pages : 396
Book Description
The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator. In his controversial bestseller Darwin’s Black Box, biochemist Michael Behe challenged Darwin’s theory of evolution, arguing that science itself has proven that intelligent design is a better explanation for the origin of life. In Darwin Devolves, Behe advances his argument, presenting new research that offers a startling reconsideration of how Darwin’s mechanism works, weakening the theory’s validity even more. A system of natural selection acting on random mutation, evolution can help make something look and act differently. But evolution never creates something organically. Behe contends that Darwinism actually works by a process of devolution—damaging cells in DNA in order to create something new at the lowest biological levels. This is important, he makes clear, because it shows the Darwinian process cannot explain the creation of life itself. “A process that so easily tears down sophisticated machinery is not one which will build complex, functional systems,” he writes. In addition to disputing the methodology of Darwinism and how it conflicts with the concept of creation, Behe reveals that what makes Intelligent Design unique—and right—is that it acknowledges causation. Evolution proposes that organisms living today are descended with modification from organisms that lived in the distant past. But Intelligent Design goes a step further asking, what caused such astounding changes to take place? What is the reason or mechanism for evolution? For Behe, this is what makes Intelligent Design so important.
Science in Action
Author: Bruno Latour
Publisher: Harvard University Press
ISBN: 9780674792913
Category : History
Languages : en
Pages : 292
Book Description
From weaker to stronger rhetoric : literature - Laboratories - From weak points to strongholds : machines - Insiders out - From short to longer networks : tribunals of reason - Centres of calculation.
Publisher: Harvard University Press
ISBN: 9780674792913
Category : History
Languages : en
Pages : 292
Book Description
From weaker to stronger rhetoric : literature - Laboratories - From weak points to strongholds : machines - Insiders out - From short to longer networks : tribunals of reason - Centres of calculation.