Author: Pieter Steyn
Publisher: Elsevier
ISBN: 0323149936
Category : Science
Languages : en
Pages : 449
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Book Description
The Biosynthesis of Mycotoxins: A Study in Secondary Metabolism focuses on the biosynthetic analysis of mycotoxins, which are inherently a heterogeneous group of metabolites that are formed along the terpene route and the route polyketide, as well as from amino acids. This book discusses the unique biological properties and structural complexity of the highly specialized secondary microbial metabolites. Organized into 12 chapters, this book starts with an overview of the characteristics of secondary metabolites, including their problematic function and the combination of their structural diversity with their restricted biological occurrence. This text then explains the sporadic occurrence of the mycotoxins as fungal metabolites. Other chapters explore ergochromes, which are a group of light yellow mycotoxins that are isolated from ergot, mold fungi, and lichens. The final chapter discusses the biosynthesis of several unrelated fungal metabolites for which toxicological data are reported. Biochemists, organic chemists, mycologists, enzymologists, plant pathologists, toxicologists, and graduate students will find this book useful.
Author: Mahendra Rai
Publisher: Springer Science & Business Media
ISBN: 3642007252
Category : Science
Languages : en
Pages : 407
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Book Description
Mycotoxins are made by different biosynthetic pathways, and they have an extremely wide range of pharmacological effects. This book will update readers on several cutting-edge aspects of mycotoxin research, including topics such as: new analytical methods for detection; the adoption of an ancient Mexican process for detoxification of aflatoxins; mycotoxin management in Ireland, Lithuania and South America; mycotoxin reduction through plant breeding and integrated management practices; and natural aflatoxin inhibitors from medicinal plants. Further contributions examine ochratoxins, selected trichothecenes, zearalenone, and aflatoxin-like gene clusters, as well as sclerotial development in Aspergillus flavus and A. parasiticus. Of particular interest are the chapters on the potential use of mycotoxins as bioweapons. This book will stimulate new thinking on the need to develop therapeutic as well as preventative interventions to reduce the toxicological threat of mycotoxins.
Author: Solomon Kadis
Publisher: Elsevier
ISBN: 1483259684
Category : Medical
Languages : en
Pages : 419
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Book Description
Microbial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields. The text is divided into three sections. Section A covers coumarins — its isolation, identification, biological action, natural occurrence, and uses. Section B deals with the epizootiology, clinical characteristics, and pathological findings of Stachybotryotoxicosis. Section C talks about phytopathogenic and helminthosporium toxins, toxic peptides found in Amanita species as well as other mushroom toxins, compounds accumulating in plants after an infection, and ergot. The book is recommended for microbiologists and toxicologists, especially those who would like to know more about the toxins produced by algae and fungi and their effects.
Author: Andreas Vogel
Publisher: John Wiley & Sons
ISBN: 3527343857
Category : Science
Languages : en
Pages : 430
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Book Description
This reference is a "must-read": It explains how an effective and economically viable enzymatic process in industry is developed and presents numerous successful examples which underline the efficiency of biocatalysis.
Author: Anne E. Desjardins
Publisher: American Phytopathological Society
ISBN:
Category : Science
Languages : en
Pages : 280
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Book Description
Also included is a thorough review of the molecular genetics of both trichothecene and fumonisin biosynthesis, presenting more than 15 years of molecular biological research in an accessible form. Part one then reviews the natural occurrence and toxicity of agriculturally important mycotoxins, with historical case studies of suspected mycotoxicoses in humans and animals. These chapters also contain updates on the molecular genetics of additional mycotoxins and the importance of mycotoxins in plant diseases. This useful reference presents concise descriptions of mycotoxin-producing Fusarium species, as defined by the most recent concepts of fungal species biology and evolution. Each species' report includes a risk assessment based on its mycotoxin profile, occurrence in food and feed crops, and association with human and animal mycotoxicoses. Data on species distribution, mycotoxin profiles, and animal toxicity facilitate risk assessment for food and feed safety.
Author: Chiara Dall'Asta
Publisher: Royal Society of Chemistry
ISBN: 1782622578
Category : Medical
Languages : en
Pages : 222
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Book Description
The first book to cover this fast developing field, Masked Mycotoxins in Food will provide a full overview of the issues relating to the toxicology of masked mycotoxins present in food products. Mycotoxins are naturally occurring chemicals produced by moulds that can grow on crops and foodstuffs. Masked mycotoxins are modified mycotoxins, due to this modification many cannot be detected using standard analytical techniques, for example HPLC and ELISA, and further research is needed to understand the health risks and threats from these modified compounds.Masked mycotoxin research is an area of toxicological research that has gained significant interest and momentum in recent years. The aim of this book is to provide a full picture of the topic, from the masked mycotoxin formation in plants to their catabolic fate in humans. The book also provides new insights and will highlight possible gaps in the knowledge base of this relatively new area. Edited and written by World renowned experts working within the field, this book is of interest to toxicologists and biochemists, but also food scientists and agricultural researchers working in industry and academia.
Author: Daniel Porter
Publisher:
ISBN: 9781634837156
Category : MEDICAL
Languages : en
Pages : 127
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Book Description
The mycotoxin ochratoxin A (OTA) is a secondary metabolite of certain fungi that may be present in food and feed. Consumption of contaminated food or feed may be harmful for humans and animals. This book aims at giving an overview of several aspects of OTA and the public and economic benefits of reducing OTA contamination in food. Other chapters focus on the use of plant extracts, essential oils and substances isolated from them for the control of ochratoxigenic fungi and ochratoxin production and its carcinogenic effects on animals.
Author: David L. Eaton
Publisher: Elsevier
ISBN: 1483288455
Category : Medical
Languages : en
Pages : 571
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Book Description
Aflatoxins, natural fungal toxins found in foods and animal feeds, have great public health significance. This book presents the basic and applied toxicology of aflatoxins, including analytical identification, agricultural and veterinary implications, toxicology and carcinogenesis in humans, and economic and regulatory problems associated with aflatoxin contamination and control. - Molecular mechanisms of aflatoxin toxicity - Analytical issues in sampling and analysis - Regulatory and economic issues associated with aflatoxin contamination of food and feed - Presentation of human and animal toxicology, veterinary, and agricultural issues related to aflatoxin contamination
Author: Jean-Michel Mérillon
Publisher:
ISBN: 9783319194561
Category : Fungi
Languages : en
Pages :
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Book Description
Author: Antonio Moretti
Publisher: Humana
ISBN: 9781493967056
Category : Science
Languages : en
Pages : 0
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Book Description
This thorough volume explores the possibility of detecting and identifying toxigenic fungi, able to produce secondary metabolites known as mycotoxins, which cause severe health problems in humans and animals after exposure to contaminated food and feed, having a broad range of toxic effects, including carcinogenicity, neurotoxicity, and reproductive and developmental toxicity. Beginning with a section on fungal genera and species of major significance along with their associated mycotoxins, the book continues with sections on Polymerase Chain Reaction (PCR)-based methods for the detection and identification of mycotoxigenic fungi, PCR-based methods for multiplex detection of mycotoxigenic fungi, as well as sections on combined approaches and new methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mycotoxigenic Fungi: Methods and Protocols will aid researchers working in this vital field to provide insight into possible actions to reduce mycotoxin contamination of crop plants and the food/feed byproducts.
