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Author:
Publisher: Academic Press
ISBN: 0128167610
Category : Science
Languages : en
Pages : 454
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Book Description
CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the CRISPR-Cas Enzymes
Author:
Publisher: Academic Press
ISBN: 0128167610
Category : Science
Languages : en
Pages : 454
Get Book Here
Book Description
CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the CRISPR-Cas Enzymes
Author:
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 828
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Book Description
Vols. 36- include Proceedings of the Biochemical Society.
Author:
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 816
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Book Description
Author: D. Hardie
Publisher: Springer Science & Business Media
ISBN: 9401131082
Category : Science
Languages : en
Pages : 313
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Book Description
The central theme of this book is that systems of cell-cell signalling via nerves, hormones, local mediators and growth factors are not distinct phenomena, but branches of one general mechanism. These topics therefore can and should be discussed in an integrated manner, and the division of cell signalling studies into separate pigeonholes such as neuroscience, endocrinology or cancer biology is unnecessary, if not counterproductive. I also believe it to be unfortunate that there is not a collective term to describe neurotransmitters, hormones, local mediators and growth factors, other than clumsy phrases such as "extracellular signal molecule". The lack of a short and distinctive word for these entities genuinely hampers people from thinking about them in an integrated way. Having decided that it was presumptuous to invent a new term, I have chosen in this book the term first messenger to cover all types of extracellular signal molecule, because of the widespread acceptance of the term second messenger to represent the intracellular signal molecules that are produced in response to many of them. I have given the book the title "biochemical messengers", which is a global term to cover both first and second messengers. The impetus for writing the book came, as must often be the case, when I had to put together a course on cell-cell signalling for biochemistry students at the University of Dundee.
Author: Thomas Scheper
Publisher: Springer Science & Business Media
ISBN: 9783540403791
Category : Science
Languages : en
Pages : 328
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Book Description
With contributions by numerous experts
Author: Pater W. Hochachka
Publisher: Princeton University Press
ISBN: 1400855411
Category : Science
Languages : en
Pages : 559
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Book Description
This book discusses biochemical adaptation to environments from freezing polar oceans to boiling hot springs, and under hydrostatic pressures up to 1,000 times that at sea level. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Author: R. Gandour
Publisher: Springer Science & Business Media
ISBN: 1468499785
Category : Science
Languages : en
Pages : 625
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Book Description
The transItIOn-state theory has been, from the point of its inception, the most influential principle in the development of our knowledge of reaction mechanisms in solution. It is natural that as the field of biochemical dynamics has achieved new levels of refinement its students have increasingly adopted the concepts and methods of transition-state theory. Indeed, every dynamical problem of biochemistry finds its most elegant and economical statement in the terms of this theory. Enzyme catalytic power, for example, derives from the interaction of enzyme and substrate structures in the transition state, so that an understanding of this power must grow from a knowledge of these structures and interactions. Similarly, transition-state interactions, and the way in which they change as protein structure is altered, constitute the pivotal feature upon which molecular evolution must turn. The complete, coupled dynamical system of the organism, incorporating the transport of matter and energy as well as local chemical processes, will eventually have to yield to a description of its component transition-state structures and their energetic response characteristics, even if the form of the description goes beyond present-day transition-state theory. Finally, the importance of biochemical effectors in medicine and agriculture carries the subject into the world of practical affairs, in the use of transition-state information for the construction of ultra potent biological agents.
Author: Gerhard Michal
Publisher: John Wiley & Sons
ISBN: 1118656881
Category : Science
Languages : en
Pages : 420
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Book Description
The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “... highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)
Author: R. Freedland
Publisher: Springer Science & Business Media
ISBN: 9400957327
Category : Science
Languages : en
Pages : 63
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Book Description
Though the major emphasis of this book will be references to several basic texts are given at the to provide the nutritionist with a biochemical end of the introduction. approach to his experimental and practical To facilitate easy reference, the book has problems, it is hoped that the book will also be been divided into chapters according to the of use to the biochemist and physiologist to roles of the basic nutrients in metabolism. demonstrate how dietary nutrition manipula Within chapters, discussion will include such tion can be used as a powerful tool in solving topics as the effects of nutrients on metabolism, problems in both physiology and biochemistry. the fate of nutrien ts, the roles of various tissues There will be no attempt to write an all-encom and interaction of tissues in utilizing nutrients, passing treatise on the relationship between and the biochernical mechanisms involved. biochemistry and nutrition; rather, it is hoped Toward the end of the book, several example that the suggestions and partial answers offered problems will be presented, which we hope will here will provide the reader with a basis for provide the reader with the opportunity to approaching problems and designing experi form testable hypotheses and design experi ments.
Author: Eberhard O. Voit
Publisher: Cambridge University Press
ISBN: 9780521785792
Category : Medical
Languages : en
Pages : 556
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Book Description
Teaches the use of modern computational methods for the analysis of biomedical systems using case studies and accompanying software.
