Advances in Artificial Pancreas Systems

Advances in Artificial Pancreas Systems PDF Author: Ali Cinar
Publisher: Springer
ISBN: 331972245X
Category : Technology & Engineering
Languages : en
Pages : 123

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Book Description
This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep. Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.

Advances in Artificial Pancreas Systems

Advances in Artificial Pancreas Systems PDF Author: Ali Cinar
Publisher: Springer
ISBN: 331972245X
Category : Technology & Engineering
Languages : en
Pages : 123

Get Book Here

Book Description
This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep. Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.

Automated Insulin Delivery

Automated Insulin Delivery PDF Author: Dana M Lewis
Publisher: Independently Published
ISBN: 9781797763699
Category :
Languages : en
Pages : 164

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Book Description
Automated insulin delivery goes by many names: hybrid or full closed loop; artificial pancreas system (APS); "looping" and more. They are not all the same, though. You have choices, ranging from the type of pump body and CGM you want to use, to the algorithm and controller, to the interoperability and remote monitoring options, and more. Like switching from multiple daily injections to an insulin pump, switching from manual diabetes to automated insulin delivery has a learning curve. It's certainly one you can tackle. After all, you're already tackling type 1 diabetes! You already have the base knowledge and experience you need to succeed with a closed loop system, if it's right for you. But you might be wondering how to get ahead of your learning curve before you start or even choose an APS, or you've started and want to dig even deeper into optimizing how an automated insulin delivery system fits into your lifestyle. This book was written for you! It leverages the collective knowledge of the early adopters of do-it-yourself and commercial systems from the past five years and packages it into easy, understandable guides and lessons learned.In this book, you'll find new analogies to help you understand - and explain - this new method of diabetes management, and tips on how to communicate with your healthcare provider(s) about it. You'll see stories and examples from real families and individuals living with type 1 diabetes and how they benefit from artificial pancreas systems, and why they chose and continue to choose to use them. You'll be empowered to understand the basic components of artificial pancreas systems, how they work, and what questions to ask as you peruse your choices now and in the future. This book also includes a foreword by Aaron Kowalski, President and CEO of JDRF, and co-founder of the JDRF Artificial Pancreas Project. "I will immediately recommend this book not just to people looking to use a DIY closed loop system, but also to anybody looking to improve their grasp on the management of type 1 diabetes, whether patient, caregiver, or healthcare provider." - Aaron Neinstein, MD (Endocrinologist, UCSF)

Technological Advances in the Treatment of Type 1 Diabetes

Technological Advances in the Treatment of Type 1 Diabetes PDF Author: D. Bruttomesso
Publisher: Karger Medical and Scientific Publishers
ISBN: 331802337X
Category : Medical
Languages : en
Pages : 274

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Book Description
The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.

Automated Reasoning for Systems Biology and Medicine

Automated Reasoning for Systems Biology and Medicine PDF Author: Pietro Liò
Publisher: Springer
ISBN: 303017297X
Category : Computers
Languages : en
Pages : 471

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Book Description
This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computational point of view. This has generated a wealth of new knowledge in the form of computational models, whose staggering complexity makes manual analysis methods infeasible. Sound, trusted, and automated means of analysing the models are thus required in order to be able to trust their conclusions. Above all, this is crucial to engineering safe biomedical devices and to reducing our reliance on wet-lab experiments and clinical trials, which will in turn produce lower economic and societal costs. Some examples of the questions addressed here include: Can we automatically adjust medications for patients with multiple chronic conditions? Can we verify that an artificial pancreas system delivers insulin in a way that ensures Type 1 diabetic patients never suffer from hyperglycaemia or hypoglycaemia? And lastly, can we predict what kind of mutations a cancer cell is likely to undergo? This book brings together leading researchers from a number of highly interdisciplinary areas, including: · Parameter inference from time series · Model selection · Network structure identification · Machine learning · Systems medicine · Hypothesis generation from experimental data · Systems biology, systems medicine, and digital pathology · Verification of biomedical devices “This book presents a comprehensive spectrum of model-focused analysis techniques for biological systems ...an essential resource for tracking the developments of a fast moving field that promises to revolutionize biology and medicine by the automated analysis of models and data.”Prof Luca Cardelli FRS, University of Oxford

The Diabetes Textbook

The Diabetes Textbook PDF Author: Joel Rodriguez-Saldana
Publisher: Springer
ISBN: 3030118150
Category : Medical
Languages : en
Pages : 1014

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Book Description
Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.

Understanding Automated Insulin Delivery

Understanding Automated Insulin Delivery PDF Author: Dana M Lewis
Publisher:
ISBN:
Category :
Languages : en
Pages : 26

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Book Description
Automated insulin delivery is a new type of technology that uses an algorithm (a set of rules) based on continuous glucose monitor data and insulin pump data to decide whether an insulin pump should give more or less insulin. This book explains the basics of scuba diving and uses it as an analogy for how an automated insulin delivery system makes small changes to manage blood glucose levels, similar to how a scuba diver makes small changes to manage their balance (called buoyancy) in the water. This book can be used to help explain diabetes technology to kids, their friends and schoolmates, and even your family members to help them understand how this technology helps make living with diabetes easier.

Handbook of Diabetes Technology

Handbook of Diabetes Technology PDF Author: Yves Reznik
Publisher: Springer
ISBN: 3319981196
Category : Medical
Languages : en
Pages : 125

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Book Description
This book covers the main fields of diabetes management through applied technologies. The different chapters include insulin therapy through basic insulin injection therapy, external and implantable insulin pumps and the more recent approaches such as sensor augmented pumps and close-loop systems. Islet transplantation is also described through its technical aspects and clinical evaluation. Glucose measurement through blood glucose meters and continuous glucose monitoring systems are comprehensively explained. Educational tools including videogames and software dedicated to diabetes management are depicted. Lastly, Telemedicine systems devoted to data transmission, telemonitoring and decision support systems are described and their use for supporting health systems are summarized. This book will help professionals involved in diabetes management understanding the contribution of diabetes technologies for promoting the optimization of glucose control and monitoring. This volume will be helpful in current clinical practice for diabetes management and also beneficial to students.

Psychosocial Care for People with Diabetes

Psychosocial Care for People with Diabetes PDF Author: Deborah Young-Hyman
Publisher: American Diabetes Association
ISBN: 1580404391
Category : Psychology
Languages : en
Pages : 330

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Book Description
Psychosocial Care for People with Diabetes describes the major psychosocial issues which impact living with and self-management of diabetes and its related diseases, and provides treatment recommendations based on proven interventions and expert opinion. The book is comprehensive and provides the practitioner with guidelines to access and prescribe treatment for psychosocial problems commonly associated with living with diabetes.

The Discovery of Insulin

The Discovery of Insulin PDF Author: Michael Bliss
Publisher: University of Toronto Press
ISBN: 1487529139
Category : Diabetes
Languages : en
Pages : 351

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Book Description
This special centenary edition of The Discovery of Insulin celebrates a path-breaking medical discovery that has changed lives around the world.

Glucose Sensing

Glucose Sensing PDF Author: Chris D. Geddes
Publisher: Springer Science & Business Media
ISBN: 0387330151
Category : Science
Languages : en
Pages : 460

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Book Description
An essential reference for any laboratory working in the analytical fluorescence glucose sensing field. The increasing importance of these techniques is typified in one emerging area by developing non-invasive and continuous approaches for physiological glucose monitoring. This volume incorporates analytical fluorescence-based glucose sensing reviews, specialized enough to be attractive to professional researchers, yet appealing to a wider audience of scientists in related disciplines of fluorescence.