The Alkali Metal Ions: Their Role for Life PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download The Alkali Metal Ions: Their Role for Life PDF full book. Access full book title The Alkali Metal Ions: Their Role for Life by Astrid Sigel. Download full books in PDF and EPUB format.
Author: Astrid Sigel
Publisher: Springer
ISBN: 3319217569
Category : Science
Languages : en
Pages : 663
Get Book Here
Book Description
MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.
Author: Astrid Sigel
Publisher: Springer
ISBN: 3319217569
Category : Science
Languages : en
Pages : 663
Get Book Here
Book Description
MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.
Author: Pierre Rousselot-pailley
Publisher: World Scientific
ISBN: 9811261679
Category : Science
Languages : en
Pages : 520
Get Book Here
Book Description
Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.
Author: Sangeeta Pandey
Publisher: John Wiley & Sons
ISBN: 1119688833
Category : Science
Languages : en
Pages : 405
Get Book Here
Book Description
BENEFICIAL CHEMICAL ELEMENTS OF PLANTS Understand beneficial elements and their role in the future of botany and agriculture Beneficial elements are those which, while not essential to plant life, can provide stimulation and enhance plant growth. Properly harnessed, these elements can bolster plant growth in the face of environmental conditions—including drought, nutrient deficiency, and excessive soil salinity—and biotic stresses like pathogens and animal activity. As climate change and population growth pose increasingly serious challenges to agriculture and essential plant production, it has never been more important to unleash the potential of beneficial elements. Beneficial Chemical Elements of Plants is an essential resource for researchers and industry specialists looking to enhance their understanding of these elements and the range and variety of their enhancements to plant growth. Written by leading scholars in the field of plant stress tolerance and nutrient enrichment, it discusses not only the rich possibilities of beneficial elements but their mechanisms of action at both biochemical and molecular levels. It details the precise potential roles played by each major beneficial element and surveys a range of elemental responses to specific environmental conditions and plant stresses. Beneficial Chemical Elements of Plants readers will also find: Chapters covering beneficial elements including aluminum, cobalt, sodium, selenium, and silicon Discussion of application methods and typical plant responses Treatment of beneficial elements in a wider environmental context Beneficial element applications to the field of sustainable agriculture Beneficial Chemical Elements of Plants is a fundamental starting point for researchers and students in the fields of plant physiology, crop science, agriculture, and botany, as well as for professionals in the biotechnology and agricultural industries.
Author: Irena Kostova
Publisher: Bentham Science Publishers
ISBN: 9815179012
Category : Medical
Languages : en
Pages : 351
Get Book Here
Book Description
Explore the fascinating interplay between chemical elements and biological life with Biological and Medical Significance of Chemical Elements. This comprehensive handbook delves into the pivotal role that various chemical elements from the periodic table play in the intricate web of life processes. Discover how these elements impact human health, influence drug development, and contribute to essential biological pathways. Key Features: - Provides information on the occurrence and classification of chemical elements in nature - Explains the biological functions of elements from different main groups (including s-, p-, d- and f-block elements) - Includes information about the biomedical significance of platinum metals, lanthanides, and actinides - Includes a list of references for further reading This book serves as an indispensable resource for anyone interested in the medical biochemistry of chemical elements
Author: Donna Geddes
Publisher: MDPI
ISBN: 3038979309
Category : Health & Fitness
Languages : en
Pages : 450
Get Book Here
Book Description
Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, body composition and geographic residence. An understanding of these changes will lead to unravelling the adaptation of milk to the environment and its impact on the infant. In terms of the promotion of breastfeeding, health economics and epidemiology is instrumental in shaping public health policy and identifying barriers to breastfeeding. Further, basic research is imperative in order to design evidence-based interventions to improve both breastfeeding duration and women’s breastfeeding experience.
Author: Susan Miller
Publisher: Elsevier
ISBN: 0128243058
Category : Medical
Languages : en
Pages : 684
Get Book Here
Book Description
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Author: Azamal Husen
Publisher: Elsevier
ISBN: 044316083X
Category : Science
Languages : en
Pages : 497
Get Book Here
Book Description
Essential Minerals in Plant-Soil Systems: Coordination, Signaling and Interaction Under Adverse Conditions is the first book to encompass these key aspects of plant science, biochemistry, soil science and fertilizer development in a single volume. Describing the micro- and macronutrients in the plant-soil system with the help of suitable illustrations, the book connects all the pieces enabling comprehensive and connected understanding. Terrestrial plants are sessile in nature. They face various adverse environmental conditions including soil nutrient-deficiency signals, which influence overall plant growth and development. Some of the essential nutrients are unreachable to roots due to their low solubility and relative immobilization. Thus, the soil-plant system has evolved signaling, communication and coordination responses for survival under multiple adverse situations. By evolving highly sophisticated mechanisms at the cellular as well as whole-plant scale, these plants have developed ways to co-regulate these stresses in order to maintain homeostasis. Essential Minerals in Plant-Soil Systems covers recent advances in the understanding of how plants coordinate the acquisition, transport, signaling, and interaction, cross-talks between macro- and micro-nutrients in adverse environmental situations. These points are key to understanding the significance of essential, as well as beneficial, elements for sustainable plant growth and production. This book is a valuable reference for those putting research into practice in addressing stress situations, as well as providing important foundational insights for further research. - Provides a comprehensive overview of micro- and macronutrients and their interaction with phytohormones under stress conditions - Explores proteomic and genomic research into deficiencies and toxicities in plant systems - Highlights the use of nanobiotechnology for controlled release of micro- and macronutrients in the plant-soil systems
Author: Bruce Averill
Publisher:
ISBN: 9780321413703
Category : Chemistry
Languages : en
Pages : 1233
Get Book Here
Book Description
Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681087472
Category : Science
Languages : en
Pages : 317
Get Book Here
Book Description
Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following reviews: o Recent Progress on Asymmetric Synthesis of Chiral Flavanones, Chromanones, and Chromenes o Supramolecular Chemistry of Modified Amino Acids and Short Peptides o The Use of Nanocatalysts in the Synthesis of Heterocycles: A Contemporary Approach o Synthesis and Applications of 1,2,3-Triazoles o Ring C–H Functionalization of Aromatic N-Oxides.
Author: Uwe Schneider
Publisher: Royal Society of Chemistry
ISBN: 1839160217
Category : Science
Languages : en
Pages : 431
Get Book Here
Book Description
Catalysis remains a key technology in a huge number of industrial processes in the 21st century. The catalytic properties of precious metals such as platinum and palladium are well understood. However, these metals are expensive and their supply is limited. Earth-abundant elements such as iron and nickel are, as the name suggests, in plentiful supply and much cheaper to use, but research on their use in catalysis has, historically, lagged behind. As researchers and companies increasingly look for ways to reduce costs and improve the sustainability of their processes there has been a renewed interest in these earth-abundant elements. This book presents a detailed overview of current research on the catalytic uses of the most Earth-abundant elements. Highlighting the top ten most Earth-abundant elements and their various roles in modern synthetic chemistry: s-block metals (Na, K, Mg, Ca), first-row transition metals (Ti, Mn, Fe), and p-block elements (Al, Si, P). The significant stoichiometric use of these elements, and their use as acid, base, dual, and/or redox catalysts will be discussed. It will be of use to industrial and academic researchers as well as graduate students with an interest in catalysis and sustainability.
