Technology and Application of 'hairy-root' Culture PDF Download
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Author: P. M. Doran
Publisher:
ISBN:
Category :
Languages : en
Pages : 9
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Book Description
Genetically-transformed hairy roots produce a wide range of valuable compounds in vitro at levels much greater than usually found in dedifferentiated tissue. Exploitation of hairy roots for large-scale production of plant chemicals depends on our understanding of their culture requirements and production characteristics, and our ability to develop appropriate bioreactors which provide adequate mixing, mass transfer and shear protection. This paper reviews recent findings about the stability, growth patterns, alkaloid synthesis and oxygen mass-transfer properties of dense hairy-root cultures.
Author: P. M. Doran
Publisher:
ISBN:
Category :
Languages : en
Pages : 9
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Book Description
Genetically-transformed hairy roots produce a wide range of valuable compounds in vitro at levels much greater than usually found in dedifferentiated tissue. Exploitation of hairy roots for large-scale production of plant chemicals depends on our understanding of their culture requirements and production characteristics, and our ability to develop appropriate bioreactors which provide adequate mixing, mass transfer and shear protection. This paper reviews recent findings about the stability, growth patterns, alkaloid synthesis and oxygen mass-transfer properties of dense hairy-root cultures.
Author: Vikas Srivastava
Publisher: Springer Nature
ISBN: 9811540551
Category : Medical
Languages : en
Pages : 247
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Book Description
The book discusses the various methods and protocols available in hairy root culture-based research. The utilization of Agrobacterium mediated genetic transformation and establishment of hairy root cultures has paved the way for large-scale secondary metabolite production in medicinal plants. Presenting recent research and offering insights from eminent research groups, the book covers a range of topics related to hairy root-based applications, including (i) establishment of hairy roots and native production of SM (ii) yield enhancement strategies for increased SM production, like elicitation (iii) hairy roots as a tool for value-added applications such as plant-microbe interaction, characterization of plant genes and root biology studies. As such it is an informative guide and experimental manual for researchers in diverse fields of plant biology.
Author: Pauline M. Doran
Publisher: CRC Press
ISBN: 1000725332
Category : Science
Languages : en
Pages : 304
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Book Description
Hairy roots are plant roots that have been genetically transformed and can be cultured on a large scale. They can replace the whole plant in many research projects, and offer a range of technical advantages over plant cell cultures. Hairy roots are now used in studies of plant secondary metabolism and its genetic manipulation, as hosts for the production of foreign proteins, for plant propagation in agriculture, in environmental research, and for the development of new engineering technology for large-scale production of plant chemicals. Hairy root culture is an interdisciplinary science, with important and expansive applications. This volume is the first to be dedicated solely to the many facets of hairy root culture. The number of papers dedicated to hairy roots is rising exponentially, and with the increasing amount of research already underway this forms a timely publication. It is written and edited by acknowledged experts in the areas of hairy root culture and product synthesis, plant propagation, bio-processing and environmental aspects of hairyroots.
Author: Sonia Malik
Publisher: Springer
ISBN: 3319697692
Category : Science
Languages : en
Pages : 225
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Book Description
This book provides the latest information about hairy root culture and its several applications, with special emphasis on potential of hairy roots for the production of bioactive compounds. Due to high growth rate as well as biochemical and genetic stability, it is possible to study the metabolic pathways related to production of bioactive compounds using hairy root culture. Chapters discuss the feasibility of hairy roots for plant derived natural compounds. Advantages and difficulties of hairy roots for up-scaling studies in bioreactors are included as well as successful examples of hairy root culture of plant species producing bioactive compounds used in food, flavors and pharmaceutical industry. This book is a valuable resource for researchers and students working on the area of plant natural products, phytochemistry, plant tissue culture, medicines, and drug discovery.
Author: Kishan Gopal Ramawat
Publisher: Springer Science & Business Media
ISBN: 354074603X
Category : Science
Languages : en
Pages : 391
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Book Description
This book on medicinal plant biotechnology covers recent developments in this field. It includes a comprehensive up-to-date survey on established medicinal plants and on molecules which gained importance in recent years. No recently published book has covered these carefully selected topics. The contributing scientists have been selected on the basis of their involvement in the related plant material as evident by their internationally recognised published work.
Author: Vikas Srivastava
Publisher: Springer
ISBN: 9811325626
Category : Science
Languages : en
Pages : 342
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Book Description
The growing scale of plant-based chemicals for industrial use has generated considerable interest in developing methods to meet their desired production levels. Among various available strategies for their production, the development of Agrobacterium rhizogenes mediated hairy root cultures (HRCs) is generally considered the most feasible approach. Additionally, several proof-of-principle experiments have demonstrated the practical feasibility of HRCs in the plant-based remediation of environment pollutants, biotransformation of important compounds, and production of therapeutic proteins. Given that hairy root biotechnology has now been recognized as a promising and highly dynamic research area, this book offers a timely update on recent advances, and approaches hairy roots as a multifaceted biological tool for various applications. Further, it seeks to investigate the loopholes in existing methodologies, identify remaining challenges and find potential solutions by presenting well thought-out scientific discussions from various eminent research groups working on hairy root biotechnology. This book provides detailed conceptual and practical information on HRC-based research, along with relevant case studies. The content is divided into three broad sections, namely (i) Hairy Roots and Secondary Metabolism, (ii) Progressive Applications, and (iii) Novel Approaches and Future Prospects. By informing the research and teaching community about the major strides made in HRC-based interventions in plant biology and their applications, the book is sure to spark further research in this fascinating field.
Author: Saurabh Bhatia
Publisher: Academic Press
ISBN: 9780128022214
Category : Medical
Languages : en
Pages : 0
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Book Description
Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications.
Author:
Publisher:
ISBN: 9783319320045
Category :
Languages : en
Pages :
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Book Description
Author: Kee-Yoeup Paek
Publisher: Springer
ISBN: 9401792232
Category : Science
Languages : en
Pages : 708
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Book Description
The bioactive compounds of plants have world-wide applications in pharmaceutical, nutraceutical and food industry with a huge market. In this book, a group of active researchers have addressed on the most recent advances in plant cell and organ cultures for the production of biomass and bioactive compounds using bioreactors. Tremendous efforts have been made to commercialize the production of plant metabolites by employing plant cell and organ cultures in bioreactors. This book emphasizes on the fundamental topics like designing of bioreactors for plant cell and organ cultures, various types of bioreactors including stirred tank, airlift, photo-bioreactor, disposable bioreactor used for plant cell and organ cultures and the advantages and disadvantages of bioreactor cultures. Various strategies for biomass production and metabolite accumulation have been discussed in different plant systems including Korean/Chinese ginseng, Siberian ginseng, Indian ginseng, Echinacea, St. John’s wort, Noni, Chinese licorice, Caterpillar fungus and microalgae. Researches on the industrial application of plant cells and organs with future prospects as well as the biosafety of biomass produced in bioreactors are also described. The topics covered in this book, such as plant cell and organ cultures, hairy roots, bioreactors, bioprocess techniques, will be a valuable reference for plant biotechnologists, plant biologists, pharmacologists, pharmacists, food technologists, nutritionists, research investigators of healthcare industry, academia, faculty and students of biology and biomedical sciences. The multiple examples of large-scale applications of cell and organ cultures will be useful and significant to industrial transformation and real commercialization.
Author: Vijai G. Gupta
Publisher: Elsevier
ISBN: 0444635041
Category : Medical
Languages : en
Pages : 378
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Book Description
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. Compiles the latest developments in the area of microbial secondary metabolites Authored by the top international researchers in this area Includes information related to nearly all areas of a microbial secondary metabolites system
