Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition PDF Author: Shan S. Wong
Publisher: CRC Press
ISBN: 084937491X
Category : Medical
Languages : en
Pages : 624

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Book Description
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivity and resolution have facilitated the analysis of cross-linked products. Updated to reflect the advances of the 21st century, this book offers: An overview of the chemical principles underlying the processes of cross-linking and conjugation A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition

Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation, Second Edition PDF Author: Shan S. Wong
Publisher: CRC Press
ISBN: 084937491X
Category : Medical
Languages : en
Pages : 624

Get Book Here

Book Description
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross-linking reagents, and advances have also been made in the area of biosensors and microarray biochips for the detection and analysis of genes, proteins, and carbohydrates. In addition, developments in physical techniques with unprecedented sensitivity and resolution have facilitated the analysis of cross-linked products. Updated to reflect the advances of the 21st century, this book offers: An overview of the chemical principles underlying the processes of cross-linking and conjugation A thorough list of cross-linking reagents published in the literature since the first edition, covering monofunctional, homobifunctional, heterobifunctional, multifunctional, and zero-length cross-linkers Reviews of the use of these reagents in studying protein tertiary structures, geometric arrangements of subunits within complex proteins and nucleic acids, near-neighbor analysis, protein-to-protein or ligand–receptor interactions, and conformational changes of biomolecules Discusses the application of immunoconjugation for immunoassays, immunotoxins for targeted therapy, microarray technology for analysis of various biomolecules, and solid state chemistry for immobilizations

Chemistry of Protein Conjugation and Cross-Linking

Chemistry of Protein Conjugation and Cross-Linking PDF Author: Shan S. Wong
Publisher: CRC Press
ISBN: 9780849358869
Category : Medical
Languages : en
Pages : 360

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Book Description
Chemical cross-linking reagents have attained great practical use in industry as well as in basic research, and an understanding of their fundamental principles of reaction is paramount to their applications. With broad coverage of the development and application of these reagents, Chemistry of Protein Conjugation and Cross-Linking discusses the mechanism of reaction and allows you to put the theory into practice. The book offers an explanation of the underlying mechanism of chemical modification, surveys all the bifunctional reagents used in bioconjugation and cross-linking, and provides a review of practical applications of these reagents in various areas of biochemistry, molecular biology, biotechnology, nucleic acid chemistry, immunochemistry, and diagnostic and biomedical disciplines. It contains numerous examples and illustrations, plus step-by-step explanations to reaction procedures. It is an excellent introduction and a comprehensive reference about chemical modification.

Peer-to-Peer Computing

Peer-to-Peer Computing PDF Author: Yu-Kwong Ricky Kwok
Publisher: CRC Press
ISBN: 1439809348
Category : Computers
Languages : en
Pages : 218

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Book Description
While people are now using peer-to-peer (P2P) applications for various processes, such as file sharing and video streaming, many research and engineering issues still need to be tackled in order to further advance P2P technologies. Peer-to-Peer Computing: Applications, Architecture, Protocols, and Challenges provides comprehensive theoretical and practical coverage of the major features of contemporary P2P systems and examines the obstacles to further success. Setting the stage for understanding important research issues in P2P systems, the book first introduces various P2P network architectures. It then details the topology control research problem as well as existing technologies for handling topology control issues. The author describes novel and interesting incentive schemes for enticing peers to cooperate and explores recent innovations on trust issues. He also examines security problems in a P2P network. The final chapter addresses the future of the field. Throughout the text, the highly popular P2P IPTV application, PPLive, is used as a case study to illustrate the practical aspects of the concepts covered. Addressing the unique challenges of P2P systems, this book presents practical applications of recent theoretical results in P2P computing. It also stimulates further research on critical issues, including performance and security problems.

Watermarking Systems Engineering

Watermarking Systems Engineering PDF Author: Mauro Barni
Publisher: CRC Press
ISBN: 9780203913512
Category : Computers
Languages : en
Pages : 496

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Book Description
The growth of the Internet has fueled the demand for enhanced watermarking and data hiding technologies and has stimulated research into new ways to implement watermarking systems in the real world. This book presents the principles of watermarking system design and discusses technologies in information concealment and recovery. It highlights the requirements and challenges of applications in security, image/video indexing, hidden communications, image captioning, and transmission error recovery and concealment. It explains digital watermarking technologies and offers an understanding of new approaches and applications, laying the groundwork for further developments in the field.

Introduction to Privacy-Preserving Data Publishing

Introduction to Privacy-Preserving Data Publishing PDF Author: Benjamin C.M. Fung
Publisher: CRC Press
ISBN: 1420091506
Category : Computers
Languages : en
Pages : 374

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Book Description
Gaining access to high-quality data is a vital necessity in knowledge-based decision making. But data in its raw form often contains sensitive information about individuals. Providing solutions to this problem, the methods and tools of privacy-preserving data publishing enable the publication of useful information while protecting data privacy. Int

Distributed Multimedia Database Technologies Supported by MPEG-7 and MPEG-21

Distributed Multimedia Database Technologies Supported by MPEG-7 and MPEG-21 PDF Author: Harald Kosch
Publisher: CRC Press
ISBN: 0203009339
Category : Computers
Languages : en
Pages : 276

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Book Description
A multimedia system needs a mechanism to communicate with its environment, the Internet, clients, and applications. MPEG-7 provides a standard metadata format for global communication, but lacks the framework to let the various players in a system interact. MPEG-21 closes this gap by establishing an infrastructure for a distributed multimedia frame

Strategic Software Engineering

Strategic Software Engineering PDF Author: Fadi P. Deek
Publisher: CRC Press
ISBN: 1420031112
Category : Computers
Languages : en
Pages : 361

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Book Description
The pervasiveness of software in business makes it crucial that software engineers and developers understand how software development impacts an entire organization. Strategic Software Engineering: An Interdisciplinary Approach presents software engineering as a strategic, business-oriented, interdisciplinary endeavor, rather than simply a technica

Software Requirements

Software Requirements PDF Author: Rick Lutowski
Publisher: CRC Press
ISBN: 9781420031317
Category : Computers
Languages : en
Pages : 274

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Book Description
Software Requirements: Encapsulation, Quality, and Reuse describes how to make requirements easy to change by using encapsulation. It introduces the Freedom methodology that shows how to encapsulate requirements thereby promoting reuse and quality. Encapsulating requirements reduces software life cycle costs by making requirements and the code that

Privacy-Aware Knowledge Discovery

Privacy-Aware Knowledge Discovery PDF Author: Francesco Bonchi
Publisher: CRC Press
ISBN: 1439803668
Category : Computers
Languages : en
Pages : 527

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Book Description
Covering research at the frontier of this field, Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques presents state-of-the-art privacy-preserving data mining techniques for application domains, such as medicine and social networks, that face the increasing heterogeneity and complexity of new forms of data. Renowned authorities

Introduction to the Semantic Web and Semantic Web Services

Introduction to the Semantic Web and Semantic Web Services PDF Author: Liyang Yu
Publisher: CRC Press
ISBN: 1584889349
Category : Computers
Languages : en
Pages : 368

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Book Description
Even though the semantic Web is a relatively new and dynamic area of research, a whole suite of components, standards, and tools have already been developed around it. Using a concrete approach, Introduction to the Semantic Web and Semantic Web Services builds a firm foundation in the concept of the semantic Web, its principal technologies, its rea