Studies on the Regulation of Transcriptional Initiation by Human RNA Polymerase II PDF Download
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Author: Xiaoqing Sun
Publisher:
ISBN:
Category :
Languages : en
Pages : 298
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Author: Xiaoqing Sun
Publisher:
ISBN:
Category :
Languages : en
Pages : 298
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Author: Michael Justin Blau
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Jason Nicholas Kuehner
Publisher:
ISBN:
Category :
Languages : en
Pages : 188
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Author: Maud Forsberg
Publisher:
ISBN: 9789155436599
Category : Genetic transcription
Languages : en
Pages : 73
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Author: Ronald C. Conaway
Publisher: Raven Press (ID)
ISBN:
Category : Science
Languages : en
Pages : 600
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Presents a coherent account of many productive lines of investigation, organized as a series of mini-reviews that focus on major research areas including studies on the structure and mechanisms of action of bacterial, viral, and eukaryotic RNA polymerases, and the transcription factors that control their activities. Each review provides a brief but up-to-date account of the progress of research in a particular area, a discussion of the major issues and questions driving that research, and a brief description of the evolving approaches and technologies used to address those questions. Annotation copyright by Book News, Inc., Portland, OR
Author: Martin Josef Seizl
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Author: Haini Cai
Publisher:
ISBN:
Category :
Languages : en
Pages : 280
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Author: Rachel Imoberdorf
Publisher:
ISBN:
Category :
Languages : en
Pages : 130
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Transcription occurs in a repressive chromatin context. Chromatin modifications are therefore often required to allow transcriptional activation. Here, we addressed the question whether global histone acetylation is involved in the regulation of transcriptional activation of class II promoters. We show that global histone acetylation has a role in activation of RNA polymerase II dependent transcription by modulating the inherent inhibitory effects of chromatin on the formation of the pre-initiation complex. In a second project we have developed a chromatin immunoprecipitation based assay that allows the study of transcriptional reinitiation "in vivo". Our results suggest the formation of a reinitiation scaffold on the GAL1, but not the ACT1 promoter. In a third project assessed whether TFIIB reaches promoters in the form of the holoenzyme "in vivo". Our data indicate that TFIIB does not assemble in a holoenzyme but associates with another, yet unidentified, factor(s) prior to promoter binding.
Author: Helen Cho
Publisher:
ISBN:
Category :
Languages : en
Pages : 346
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Author: Tae-Kyung Kim
Publisher:
ISBN:
Category :
Languages : en
Pages : 292
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