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Author: A RobertYokel
Publisher: CRC Press
ISBN: 9781439805671
Category : Medical
Languages : en
Pages : 272
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Book Description
This work focuses primarily on identifying the research needs in this area of neurotoxicology. Based on papers presented for the International Symposium on Aluminium Toxicity, held in Vancouver in 1995, it reviews the knowledge and research required in each specific area.
Author: A RobertYokel
Publisher: CRC Press
ISBN: 9781439805671
Category : Medical
Languages : en
Pages : 272
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Book Description
This work focuses primarily on identifying the research needs in this area of neurotoxicology. Based on papers presented for the International Symposium on Aluminium Toxicity, held in Vancouver in 1995, it reviews the knowledge and research required in each specific area.
Author: Sung-Woo Cho
Publisher:
ISBN:
Category : Aluminum
Languages : en
Pages : 84
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Book Description
Author: Robert A. Yokel
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309171938
Category : Nature
Languages : en
Pages : 534
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Book Description
Ignition of upholstered furniture by small open flames from matches, cigarette lighters, and candles is one of the leading causes of residential-fire deaths in the United States. These fires accounted for about 16% of civilian fire deaths in 1996. On average, each year since 1990, about 90 deaths (primarily of children), 440 injuries, and property losses amounting to 50 million dollars have resulted from fires caused by the ignition of upholstered furniture by small open flames. Certain commercial seating products (such as aircraft and bus seats) are subject to flammability standards and sometimes incorporate FR-treated upholstery cover materials, but there is no federal-government requirement for residential upholstered furniture, and it is generally not treated with FR chemicals. It is estimated that less than 0.2% of all U.S. residential upholstery fabric is treated with flame-retardant (FR) chemicals. The Consumer Product Safety Act of 1972 created the U.S. Consumer Product Safety Commission (CPSC) as an independent federal regulatory agency whose mission is to protect the public from unreasonable risks of injury and death associated with consumer products. CPSC also administers the Flammable Fabrics Act, under which it regulates flammability hazards and the Federal Hazardous Substances Act (FHSA), which regulates hazardous substances including chemicals. In 1993, the National Association of State Fire Marshals petitioned CPSC to issue a performance-based flammability standard for upholstered furniture to reduce the risk of residential fires. The Commission granted that portion of the petition relating to small open flame ignition risks. In response to concerns regarding the safety of FR chemicals, Congress, in the fiscal year 1999 appropriations report for CPSC, requested that the National Research Council conduct an independent study of the health risks to consumers posed by exposure to FR chemicals that are likely to be used in residential upholstered furniture to meet a CPSC standard. The National Research Council assigned the project to the Committee on Toxicology (COT) of the Commission on Life Sciences' Board on Environmental Studies and Toxicology. COT convened the Subcommittee on Flame-Retardant Chemicals, which prepared this report. Subcommittee members were chosen for their recognized expertise in toxicology, pharmacology, epidemiology, chemistry, exposure assessment, risk assessment, and biostatistics. Toxicological Risks of Selected Flame-Retardant Chemicals is organized into 18 chapters and two appendices. Chapter 2 describes the risk assessment process used by the subcommittee in determining the risk associated with potential exposure to the various FR chemicals. Chapter 3 describes the method the subcommittee used to measure and estimate the intensity, frequency, extent, and duration of human exposure to FR chemicals. Chapters 4-19 provide the subcommittee's review and assessment of health risks posed by exposure to each of the 16 FR chemicals. Data gaps and research needs are provided at the end of these chapters.
Author: Qiao Niu
Publisher: Springer
ISBN: 9811313709
Category : Medical
Languages : en
Pages : 191
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Book Description
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
Author: Nabil Abdel-Maksoud Abdalla
Publisher:
ISBN:
Category : Aluminum in the body
Languages : en
Pages : 290
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Book Description
Author: T. Lewis
Publisher: CRC Press
ISBN: 9780873711944
Category : Science
Languages : en
Pages : 358
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Book Description
This valuable new book examines the sources, fate, transport, and health effects of aluminum in aquatic and terrestrial environments. Concisely written by leading experts, Environmental Chemistry and Toxicology of Aluminum bridges numerous scientific disciplines that are conducting research on this once-believed innocuous element. Included in this comprehensive publication are: the latest advances in the study of aluminum in the environment; toxicity research-aquatic and terrestrial biota; neurotoxicity and possible links to Alzheimer's disease; different forms of aluminum in soils and soil water; coordination chemistry; specification and analytical methods; mobilization into subsurface waters as a result of acidic deposition; aluminum chemistry in soils and plant toxicity; effects in aquatic and terrestrial ecosystems; and aluminum research in drinking and ground water. This is an ACS Environmental Chemistry Division book.
Author: Watson Harry Everhart
Publisher:
ISBN:
Category : Aquatic animals
Languages : en
Pages : 64
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Book Description
Author: C. Exley
Publisher: Elsevier
ISBN: 0080525504
Category : Science
Languages : en
Pages : 453
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Book Description
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to impact upon mammalian physiology and function and range from clinical studies, through animal models of disease to the detailed biochemistry of aluminium toxicity. Chapters are also included on epidemiology and other factors involved in the aetiology of Alzheimer's.This is the first time that this subject has been treated in such a comprehensive manner. The research detailed in each chapter, includes the latest research in the field, it has been critically appraised and this appraisal has been used by each author to present an informed opinion of its relevance to aluminium and Alzheimer's disease. The chapters are much more than reviews; they are a statement of the state of the art and of what the future may hold for research in this field. As a whole they show the high quality of research that has been carried out in our efforts to understand the toxicity of aluminium in man and that we are far away from discounting the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease.
Author: H. J. Gitelman
Publisher: CRC Press
ISBN: 9780824780265
Category : Technology & Engineering
Languages : en
Pages : 318
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Book Description
A hot topic. Contributors address: guidelines for sampling and analyzing aluminum levels in the body, how acid rain alters aluminum in the typical North American diet, the alleged link between aluminum and Alzheimer's disease, the role of aluminum in the dynamics of bone physiology, occupational exp
