Structural studies of the Escherichia coli 70S ribosome PDF Download
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Author: Barbara-S. Schuwirth
Publisher:
ISBN:
Category :
Languages : de
Pages :
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Author: Barbara-S. Schuwirth
Publisher:
ISBN:
Category :
Languages : de
Pages :
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Author: Leonard Charles Lutter
Publisher:
ISBN:
Category :
Languages : en
Pages : 344
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Author: Anders Liljas
Publisher: World Scientific
ISBN: 9814531804
Category : Science
Languages : en
Pages : 494
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Book Description
This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and cryo-EM forms part of an interactive framework that involves biochemistry and molecular computation. The book provides a comprehensive overview of translation in light of the structural results. It is a valuable resource for scientists in this and related fields, as well as for students taking courses with a focus on translation.There is no other book in this field currently except the previous edition of this book. The authors have for a long time worked in the field of structure and function of the translation system.
Author: Kan Zhang
Publisher:
ISBN: 9789171536013
Category :
Languages : en
Pages : 48
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Author: Anders Liljas
Publisher: World Scientific
ISBN: 9814482544
Category : Science
Languages : en
Pages : 339
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Book Description
This comprehensive and highly illustrated book provides a basic and up-to-date summary of translation on bacterial ribosomes, with emphasis on the structural insights. It is an attempt to present the ribosome and its functional activities in a coherent manner. Two types of illustrations are used to describe the translation field: simplified black-and-white illustrations to depict aspects of translation and color plates to give correct structural representations.The book presents essentially all aspects of the translation system, focusing on the relation between structure and function. Upper level undergraduates and graduate students with an interest in protein synthesis will find this lecture notes volume invaluable. The book is also an essential source of information for researchers who want to get an overview of translation.
Author: Marina V. Rodnina
Publisher: Springer Science & Business Media
ISBN: 3709102154
Category : Medical
Languages : en
Pages : 428
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Book Description
The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.
Author: Walter Ensign Hill
Publisher: ASM Press
ISBN:
Category : Science
Languages : en
Pages : 716
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Book Description
This book is recommended as a 'hitchhiker's guide to the ribosome' for everyone with an interest in translation, RNA-protein structures, and macromolecular structure-function relationships Science >.
Author: Eleanor Spicer Ward
Publisher:
ISBN:
Category : Ribosomes
Languages : en
Pages : 468
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Author: Raj Deepak Pai
Publisher:
ISBN:
Category :
Languages : en
Pages : 374
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Author: Michael Hons
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Life can be understood as the systematic collaborative action of several entities on molecular level reducing locally the entropy at the cost of the exterior environment. These entities are in great part macromolecular complexes composed of different proteins and ribonucleic acids. In a bottom-up approach, structural studies on macromolecular complexes can help to understand the principles of life. In this work, the structures of two very different macromolecular complexes, the human cohesin and the E. coli 70S ribosome, are studied by single particle electron microscopy. Structural studies ...
