Author: Stavros Thomopoulos
Publisher: Springer Science & Business Media
ISBN: 1461433177
Category : Technology & Engineering
Languages : en
Pages : 385
Book Description
Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.
Structural Interfaces and Attachments in Biology
Author: Stavros Thomopoulos
Publisher: Springer Science & Business Media
ISBN: 1461433177
Category : Technology & Engineering
Languages : en
Pages : 385
Book Description
Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.
Publisher: Springer Science & Business Media
ISBN: 1461433177
Category : Technology & Engineering
Languages : en
Pages : 385
Book Description
Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.
Biological Adhesives
Author: Andrew M. Smith
Publisher: Springer
ISBN: 331946082X
Category : Science
Languages : en
Pages : 380
Book Description
Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals. As we learn more about their molecular and mechanical properties we begin to understand why they adhere so well and with this comes broad applications in areas such as medicine, dentistry, and biotechnology.
Publisher: Springer
ISBN: 331946082X
Category : Science
Languages : en
Pages : 380
Book Description
Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals. As we learn more about their molecular and mechanical properties we begin to understand why they adhere so well and with this comes broad applications in areas such as medicine, dentistry, and biotechnology.
Proceedings of the American Society for Composites 2014-Twenty-ninth Technical Conference on Composite Materials
Author: Hyonny Kim
Publisher: DEStech Publications, Inc
ISBN: 1605951242
Category : Science
Languages : en
Pages : 3583
Book Description
New and not previously published U.S. and international research on composite and nanocomposite materialsFocus on health monitoring/diagnosis, multifunctionality, self-healing, crashworthiness, integrated computational materials engineering (ICME), and moreApplications to aircraft, armor, bridges, ships, and civil structures This fully searchable CD-ROM contains 270 original research papers on all phases of composite materials, presented by specialists from universities, NASA and private corporations such as Boeing. The document is divided into the following sections: Aviation Safety and Aircraft Structures; Armor and Protection; Multifunctional Composites; Effects of Defects; Out of Autoclave Processing; Sustainable Processing; Design and Manufacturing; Stability and Postbuckling; Crashworthiness; Impact and Dynamic Response; Natural, Biobased and Green; Integrated Computational Materials Engineering (ICME); Structural Optimization; Uncertainty Quantification; NDE and SHM Monitoring; Progressive Damage Modeling; Molecular Modeling; Marine Composites; Simulation Tools; Interlaminar Properties; Civil Structures; Textiles. The CD-ROM displays figures and illustrations in articles in full color along with a title screen and main menu screen. Each user can link to all papers from the Table of Contents and Author Index and also link to papers and front matter by using the global bookmarks which allow navigation of the entire CD-ROM from every article. Search features on the CD-ROM can be by full text including all key words, article title, author name, and session title. The CD-ROM has Autorun feature for Windows 2000 or higher products and can also be used with Macintosh computers. The CD includes the program for Adobe Acrobat Reader with Search 11.0. One year of technical support is included with your purchase of this product.
Publisher: DEStech Publications, Inc
ISBN: 1605951242
Category : Science
Languages : en
Pages : 3583
Book Description
New and not previously published U.S. and international research on composite and nanocomposite materialsFocus on health monitoring/diagnosis, multifunctionality, self-healing, crashworthiness, integrated computational materials engineering (ICME), and moreApplications to aircraft, armor, bridges, ships, and civil structures This fully searchable CD-ROM contains 270 original research papers on all phases of composite materials, presented by specialists from universities, NASA and private corporations such as Boeing. The document is divided into the following sections: Aviation Safety and Aircraft Structures; Armor and Protection; Multifunctional Composites; Effects of Defects; Out of Autoclave Processing; Sustainable Processing; Design and Manufacturing; Stability and Postbuckling; Crashworthiness; Impact and Dynamic Response; Natural, Biobased and Green; Integrated Computational Materials Engineering (ICME); Structural Optimization; Uncertainty Quantification; NDE and SHM Monitoring; Progressive Damage Modeling; Molecular Modeling; Marine Composites; Simulation Tools; Interlaminar Properties; Civil Structures; Textiles. The CD-ROM displays figures and illustrations in articles in full color along with a title screen and main menu screen. Each user can link to all papers from the Table of Contents and Author Index and also link to papers and front matter by using the global bookmarks which allow navigation of the entire CD-ROM from every article. Search features on the CD-ROM can be by full text including all key words, article title, author name, and session title. The CD-ROM has Autorun feature for Windows 2000 or higher products and can also be used with Macintosh computers. The CD includes the program for Adobe Acrobat Reader with Search 11.0. One year of technical support is included with your purchase of this product.
Osseointegration of Orthopaedic Implants
Author: Amirhossein Goharian
Publisher: Academic Press
ISBN: 0128133953
Category : Technology & Engineering
Languages : en
Pages : 214
Book Description
Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. - Reviews and discusses all aspects of orthopedic implant osseointegration - Provides conceptual implants for bone fracture fixation and joint replacement - Offers novel ideas for the development of orthopedic implants with superior osseointegration
Publisher: Academic Press
ISBN: 0128133953
Category : Technology & Engineering
Languages : en
Pages : 214
Book Description
Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. - Reviews and discusses all aspects of orthopedic implant osseointegration - Provides conceptual implants for bone fracture fixation and joint replacement - Offers novel ideas for the development of orthopedic implants with superior osseointegration
Advanced Materials Modelling for Structures
Author: Holm Altenbach
Publisher: Springer Science & Business Media
ISBN: 3642351670
Category : Technology & Engineering
Languages : en
Pages : 365
Book Description
This volume presents the major outcome of the IUTAM symposium on “Advanced Materials Modeling for Structures”. It discusses advances in high temperature materials research, and also to provides a discussion the new horizon of this fundamental field of applied mechanics. The topics cover a large domain of research but place a particular emphasis on multiscale approaches at several length scales applied to non linear and heterogeneous materials. Discussions of new approaches are emphasised from various related disciplines, including metal physics, micromechanics, mathematical and computational mechanics.
Publisher: Springer Science & Business Media
ISBN: 3642351670
Category : Technology & Engineering
Languages : en
Pages : 365
Book Description
This volume presents the major outcome of the IUTAM symposium on “Advanced Materials Modeling for Structures”. It discusses advances in high temperature materials research, and also to provides a discussion the new horizon of this fundamental field of applied mechanics. The topics cover a large domain of research but place a particular emphasis on multiscale approaches at several length scales applied to non linear and heterogeneous materials. Discussions of new approaches are emphasised from various related disciplines, including metal physics, micromechanics, mathematical and computational mechanics.
Advances in Protein Molecular and Structural Biology Methods
Author: Timir Tripathi
Publisher: Academic Press
ISBN: 0323902650
Category : Science
Languages : en
Pages : 716
Book Description
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Publisher: Academic Press
ISBN: 0323902650
Category : Science
Languages : en
Pages : 716
Book Description
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Structural Biology in Drug Discovery
Author: Jean-Paul Renaud
Publisher: John Wiley & Sons
ISBN: 1118900502
Category : Medical
Languages : en
Pages : 1437
Book Description
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Publisher: John Wiley & Sons
ISBN: 1118900502
Category : Medical
Languages : en
Pages : 1437
Book Description
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Catalyzing Inquiry at the Interface of Computing and Biology
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309164893
Category : Science
Languages : en
Pages : 468
Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Publisher: National Academies Press
ISBN: 0309164893
Category : Science
Languages : en
Pages : 468
Book Description
Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Structural Genomics and High Throughput Structural Biology
Author: Michael Sundstrom
Publisher: CRC Press
ISBN: 0849361435
Category : Medical
Languages : en
Pages : 304
Book Description
Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru
Publisher: CRC Press
ISBN: 0849361435
Category : Medical
Languages : en
Pages : 304
Book Description
Researchers in structural genomics continue to search for biochemical and cellular functions of proteins as well as the ways in which proteins assemble into functional pathways and networks using either experimental or computational approaches. Based on the experience of leading international experts, Structural Genomics and High Throughput Stru
Biomolecular Interfaces
Author: Ariel Fernández Stigliano
Publisher: Springer
ISBN: 3319168509
Category : Science
Languages : en
Pages : 380
Book Description
The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.
Publisher: Springer
ISBN: 3319168509
Category : Science
Languages : en
Pages : 380
Book Description
The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.