Structural Interfaces and Attachments in Biology

Structural Interfaces and Attachments in Biology PDF Author: Stavros Thomopoulos
Publisher: Springer Science & Business Media
ISBN: 1461433177
Category : Technology & Engineering
Languages : en
Pages : 385

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Book Description
Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.

Structural Interfaces and Attachments in Biology

Structural Interfaces and Attachments in Biology PDF Author: Stavros Thomopoulos
Publisher: Springer Science & Business Media
ISBN: 1461433177
Category : Technology & Engineering
Languages : en
Pages : 385

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Book Description
Attachment of dissimilar materials in engineering and surgical practice is a perennial challenge. Bimaterial attachment sites are common locations for injury, repeated injury, and mechanical failure. Nature presents several highly effective solutions to the challenge of bimaterial attachment that differ from those found in engineering practice. Structural Interfaces and Attachments in Biology describes the attachment of dissimilar materials from multiple perspectives. The text will simultaneously elucidate natural bimaterial attachments and outline engineering principles underlying successful attachments to the communities of tissue engineers and surgeons. Included an in-depth analysis of the biology of attachments in the body and mechanisms by which robust attachments are formed, a review of current concepts of attaching dissimilar materials in surgical practice and a discussion of bioengineering approaches that are currently being developed.

Textbook Of Structural Biology (Second Edition)

Textbook Of Structural Biology (Second Edition) PDF Author: Anders Liljas
Publisher: World Scientific
ISBN: 9813142499
Category : Science
Languages : en
Pages : 610

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Book Description
This book provides a comprehensive coverage of the basic principles of structural biology, as well as an up-to-date summary of some main directions of research in the field. The relationship between structure and function is described in detail for soluble proteins, membrane proteins, membranes, and nucleic acids.There are several books covering protein structure and function, but none that give a complete picture, including nucleic acids, lipids, membranes and carbohydrates, all being of central importance in structural biology.The book covers state-of-the-art research in various areas. It is unique for its breadth of coverage by experts in the fields. The book is richly illustrated with more than 400 color figures to highlight the wide range of structures.

Osseointegration of Orthopaedic Implants

Osseointegration of Orthopaedic Implants PDF Author: Amirhossein Goharian
Publisher: Academic Press
ISBN: 0128133953
Category : Technology & Engineering
Languages : en
Pages : 214

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Book Description
Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. - Reviews and discusses all aspects of orthopedic implant osseointegration - Provides conceptual implants for bone fracture fixation and joint replacement - Offers novel ideas for the development of orthopedic implants with superior osseointegration

Mechanics of Functionally Graded Material Structures

Mechanics of Functionally Graded Material Structures PDF Author: Isaac E. T. Al ELISHAKOFF
Publisher: World Scientific
ISBN: 9814656593
Category : Technology & Engineering
Languages : en
Pages : 340

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Book Description
Mechanics of Functionally Graded Material Structures is an authoritative and fresh look at various functionally graded materials, customizing them with various structures. The book is devoted to tailoring material properties to the needed structural performance. The authors pair materials with the appropriate structures based upon their purpose and use.Material grading of structures depending upon thickness, axial and polar directions are discussed. Three dimensional analysis of rectangular plates made of functional graded materials and vibrational tailoring of inhomogeneous beams and circular plates are both covered in great detail. The authors derive novel closed form solutions that can serve as benchmarks that numerical solutions can be compared to. These are published for the first time in the literature. This is a unique book that gives the first exposition of the effects of various grading mechanisms on the structural behavior as well as taking into account vibrations and buckling.

Algorithms in Structural Molecular Biology

Algorithms in Structural Molecular Biology PDF Author: Bruce R. Donald
Publisher: MIT Press
ISBN: 0262548798
Category : Science
Languages : en
Pages : 497

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Book Description
An overview of algorithms important to computational structural biology that addresses such topics as NMR and design and analysis of proteins.Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering. This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including NMR (nuclear magnetic resonance); X-ray crystallography; and the design and analysis of proteins, peptides, and small molecules. Each chapter offers a concise overview of important concepts, focusing on a key topic in the field. Four chapters offer a short course in algorithmic and computational issues related to NMR structural biology, giving the reader a useful toolkit with which to approach the fascinating yet thorny computational problems in this area. A recurrent theme is understanding the interplay between biophysical experiments and computational algorithms. The text emphasizes the mathematical foundations of structural biology while maintaining a balance between algorithms and a nuanced understanding of experimental data. Three emerging areas, particularly fertile ground for research students, are highlighted: NMR methodology, design of proteins and other molecules, and the modeling of protein flexibility. The next generation of computational structural biologists will need training in geometric algorithms, provably good approximation algorithms, scientific computation, and an array of techniques for handling noise and uncertainty in combinatorial geometry and computational biophysics. This book is an essential guide for young scientists on their way to research success in this exciting field.

Hierarchical Composite Materials

Hierarchical Composite Materials PDF Author: Kaushik Kumar
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110544024
Category : Technology & Engineering
Languages : en
Pages : 215

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Book Description
Hierarchical Composite Materials provides an in-depth analysis of a class of advanced composites that have properties that are anisotropic due to structural organization at different length scales. Chapters address how ordering occurs from the atomic-scale up to the microstructure and how control of these factors leads to the final materials' properties. Manufacturing procedures, properties, and applications of different functionally graded materials are discussed in detail. This book is ideal for materials scientists, mechanical engineers, chemists and physicists.

Biological Adhesives

Biological Adhesives PDF Author: Andrew M. Smith
Publisher: Springer
ISBN: 331946082X
Category : Science
Languages : en
Pages : 380

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Book Description
Many creatures use adhesive polymers and structures to attach to inert substrates, to each other, or to other organisms. This is the first major review that brings together research on many of the well-known biological adhesives dealing with bacteria, fungi, algae, and marine and terrestrial animals. As we learn more about their molecular and mechanical properties we begin to understand why they adhere so well and with this comes broad applications in areas such as medicine, dentistry, and biotechnology.

Ligament Reconstructions

Ligament Reconstructions PDF Author: L'hocine Yahia
Publisher: World Scientific
ISBN: 9811204640
Category : Medical
Languages : en
Pages : 403

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Book Description
The ACL or anterior cruciate ligament is the most important ligament in the knee. When it is completely torn, it can lead to instability or buckling of the knee. There are several options to choose from when selecting a graft for ACL reconstruction such as using autografts including patellar tendon, hamstring tendon, and quadriceps tendon, and allografts (also known as donor tissue or cadaver tissue). Artificial ligaments are also discussed since they are still used in Europe and Asia. This book summarizes the pros and cons of each graft option in detail.

Composite Materials

Composite Materials PDF Author: Kamal K. Kar
Publisher: Springer
ISBN: 3662495147
Category : Technology & Engineering
Languages : en
Pages : 694

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Book Description
Composite materials are used as substitutions of metals/traditional materials in aerospace, automotive, civil, mechanical and other industries. The present book collects the current knowledge and recent developments in the characterization and application of composite materials. To this purpose the volume describes the outstanding properties of this class of advanced material which recommend it for various industrial applications.

Structural Biology in Immunology

Structural Biology in Immunology PDF Author: Chaim Putterman
Publisher: Academic Press
ISBN: 0128033703
Category : Medical
Languages : en
Pages : 192

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Book Description
Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. - Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules - Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship - Features a collaborative editorial effort, involving clinical immunologists and structural biologists - Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology - Gives interested parties a bridge to learn about computer modeling and structure based design principles