Protein-Nucleic Acid Interactions PDF Download
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Author: Phoebe A. Rice
Publisher: Royal Society of Chemistry
ISBN: 0854042725
Category : Science
Languages : en
Pages : 417
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Book Description
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
Author: Phoebe A. Rice
Publisher: Royal Society of Chemistry
ISBN: 0854042725
Category : Science
Languages : en
Pages : 417
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Book Description
This book provides both in-depth background and up-to-date information in this area. The chapters are organized by general themes and principles, written by experts who illustrate topics with current findings. Topics covered include: - the role of ions and hydration in protein-nucleic acid interactions - transcription factors and combinatorial specificity - indirect readout of DNA sequence - single-stranded nucleic acid binding proteins - nucleic acid junctions and proteins, - RNA protein recognition - recognition of DNA damage. It will be a key reference for both advanced students and established scientists wishing to broaden their horizons.
Author: Hamid Bolouri
Publisher: World Scientific Publishing Company
ISBN: 1848168187
Category : Science
Languages : en
Pages : 341
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Book Description
This book serves as an introduction to the myriad computational approaches to gene regulatory modeling and analysis, and is written specifically with experimental biologists in mind. Mathematical jargon is avoided and explanations are given in intuitive terms. In cases where equations are unavoidable, they are derived from first principles or, at the very least, an intuitive description is provided. Extensive examples and a large number of model descriptions are provided for use in both classroom exercises as well as self-guided exploration and learning. As such, the book is ideal for self-learning and also as the basis of a semester-long course for undergraduate and graduate students in molecular biology, bioengineering, genome sciences, or systems biology./a
Author: Gary Stormo
Publisher:
ISBN: 9781936113491
Category : Science
Languages : en
Pages : 198
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Book Description
One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein-DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create unified view of the field and a fuller understanding of protein-DNA interactions.
Author: Gurbachan S. Miglani
Publisher: I K International Pvt Ltd
ISBN: 8197069549
Category : Science
Languages : en
Pages : 724
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Book Description
Epigenetics and Biological Processes deals with epigenetic control of various plant processes such as chromatin modification, biomacromolecule interactions, cell cycle, DNA replication, DNA recombination, DNA damage response, transcription, RNA processing and translation initiation, host restriction and modification, heterochromatin, euchromatin, centromere functions, telomeric maintenance, transposon activation, transposon silencing, transposon reactivation, photosynthesis, respiration, transpiration, polyploidisation, heterosis, homeostasis, cytoplasmic male sterility, self-incompatibility, circadian clocks, epigenetic imprinting, dosage compensation, somaclonal variation, plant stress response, plant-microbe interactions, disease responsive genes, and sustainable green revolution through epigenetics. Understanding epigenetics of these plant processes is essential for using science of epigenetics as a tool for crop improvement. This book is primarily designed as a textbook for senior/upper undergraduate (B.Sc. Agri.; B.Sc. Biotechnology and B.Tech. (Biotechnology) and graduate level (M.Sc. and Ph.D.) students studying epigenetics in conventional, agricultural and medical universities. Teachers and researchers in any discipline of life sciences, agricultural sciences, medicine, and biotechnology.
Author: Ron D Appel
Publisher: World Scientific
ISBN: 981446869X
Category : Science
Languages : en
Pages : 464
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Book Description
Biological research and recent technological advances have resulted in an enormous increase in research data that require large storage capacities, powerful computing resources, and accurate data analysis algorithms. Bioinformatics is the field that provides these resources to life science researchers.The Swiss Institute of Bioinformatics (SIB), which has celebrated its 10th anniversary in 2008, is an institution of national importance, recognized worldwide for its state-of-the-art work. Organized as a federation of bioinformatics research groups from Swiss universities and research institutes, the SIB provides services to the life science community that are highly appreciated worldwide, and coordinates research and education in bioinformatics nationwide. The SIB plays a central role in life science research both in Switzerland and abroad by developing extensive and high-quality bioinformatics resources that are essential for all life scientists. Knowledge developed by SIB members in areas such as genomics, proteomics, and systems biology is directly transformed by academia and industry into innovative solutions to improve global health. Such an astounding concentration of talent in a given field is unusual and unique in Switzerland.This book provides an insight into some of the key areas of activity in bioinformatics in Switzerland. With contributions from SIB members, it covers both research work and major infrastructure efforts in genome and gene expression analysis, investigations on proteins and proteomes, evolutionary bioinformatics, and modeling of biological systems.
Author: Yuriy L. Orlov
Publisher: Frontiers Media SA
ISBN: 2889741427
Category : Science
Languages : en
Pages : 234
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Book Description
Publisher’s note: In this 2nd edition, the following article has been updated: Orlov YL, Tatarinova TV, Oparina NY, Galieva ER and Baranova AV (2021) Editorial: Bioinformatics of Genome Regulation, Volume I. Front. Genet. 12:803273. doi: 10.3389/fgene.2021.803273
Author: Tamar Schlick
Publisher: Royal Society of Chemistry
ISBN: 1849735042
Category : Science
Languages : en
Pages : 381
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Book Description
The chemical and biological sciences face unprecedented opportunities in the 21st century. A confluence of factors from parallel universes - advances in experimental techniques in biomolecular structure determination, progress in theoretical modeling and simulation for large biological systems, and breakthroughs in computer technology - has opened new avenues of opportunity as never before. Now, experimental data can be interpreted and further analysed by modeling, and predictions from any approach can be tested and advanced through companion methodologies and technologies. This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts. With contributions from experts in the field, the books describe progress and innovation in areas including: simulation algorithms for dynamics and enhanced configurational sampling, force field development, implicit solvation models, coarse-grained models, quantum-mechanical simulations, protein folding, DNA polymerase mechanisms, nucleic acid complexes and simulations, RNA structure analysis and design and other important topics in structural biology modeling. The books are aimed at graduate students and experts in structural biology and chemistry and the emphasis is on reporting innovative new approaches rather than providing comprehensive reviews on each subject.
Author:
Publisher: Academic Press
ISBN: 148329501X
Category : Science
Languages : en
Pages : 216
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Book Description
Footprinting of Nucleic Acid-Protein Complexes provides protocols for studying the stoichiometry, binding site size and location, and structural changes in nucleic acids caused by their interaction with proteins. The methods are central to studying key biological processes, such as transcription and translation. The techniques are important to experiments in vivoand in vitro, in eukaryotes and in prokaryotes, at qualitative and quantitative levels,and across many disciplines.This book is a laboratory manual of footprinting techniques for studying nucleic acid-protein interactions. It contains clear and concise descriptions of the most important methodologies, and includes in vivo as well as in vitro applications. It is aimed at bench scientists from graduate students on, and should be of value in industrial labs as well as in academic settings. Use of different footprinting approaches can provide unique insights into DNA-protein systems. The protocols containedin this handbook are written to be"user-friendly,"and thus should be conducive to extending the use of footprinting to new systems. The section on quantitative analysis of DNAse I footprints should prove especially useful for in depth evaluation of cooperative interactions.(For the End User)Provides clear exposition of footprinting techniques for characterizing DNA-protein interactionsCovers both protection methods for identifying sites of protein binding and interference methods for determining points of contact between DNA and proteinIncludes approaches for both in vitro and in vivo measurementsHigh quality, timely, and of lasting practical value in the laboratory
Author: D. Frishman
Publisher: Springer Science & Business Media
ISBN: 3211751238
Category : Science
Languages : en
Pages : 491
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Book Description
An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale protein annotation of function and structure, annotation and prediction of protein interactions, and the organization and annotation of molecular networks and biochemical pathways. Also covered is a technical framework to organize and represent genome data using the DAS technology and work in the annotation of two large genomic sets: HIV/HCV viral genomes and splicing alternatives potentially encoded in 1% of the human genome.
Author: Diana J Vincent
Publisher: World Scientific
ISBN: 9814548332
Category :
Languages : en
Pages : 1630
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Book Description
This three volume series represents a selected and refereed collection of papers contributed by the participants of the First World Congress on Computational Medicine, Public Health, and Biotechnology, held in 1994 at Austin, Texas. Over 500 individuals, from 30 countries attended this meeting. In addition, this collection contains a number of papers from the Australian CSIRO High Performance Computing Meeting held that same year.
