Smart Nanomaterials Targeting Pathological Hypoxia

Smart Nanomaterials Targeting Pathological Hypoxia PDF Author: Sonam Chawla
Publisher: Springer Nature
ISBN: 9819917182
Category : Science
Languages : en
Pages : 418

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Book Description
The book showcases the newest research on smart nanoplatforms responding to “hypoxia”; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse pathological settings presented in chapters contributed by various experts in the field. The themes in the book touch upon critical facets to address pathological hypoxia such as nanomaterials enhancing oxygenation, hypoxia responsive nanoformulations which deliver the drug directly to the hypoxic site, limited toxicity and enhanced efficacy of smart nanoformulations to counter molecular consequences of hypoxia, and theranostics combining hypoxia detection systems with drug delivery systems. This book disseminates the current implications of smart nanomaterials in disease management that can be exploited by scholars, researchers, and pharma industries to develop, manufacture, and commercialize hypoxia targeted diagnostics and therapeutics.

Smart Nanomaterials Targeting Pathological Hypoxia

Smart Nanomaterials Targeting Pathological Hypoxia PDF Author: Sonam Chawla
Publisher: Springer Nature
ISBN: 9819917182
Category : Science
Languages : en
Pages : 418

Get Book Here

Book Description
The book showcases the newest research on smart nanoplatforms responding to “hypoxia”; an omnipresent pathological feature of many modern-day diseases and its potential applications. The book demonstrates the versatility of hypoxia targeted smart nanoplatforms in disease management in diverse pathological settings presented in chapters contributed by various experts in the field. The themes in the book touch upon critical facets to address pathological hypoxia such as nanomaterials enhancing oxygenation, hypoxia responsive nanoformulations which deliver the drug directly to the hypoxic site, limited toxicity and enhanced efficacy of smart nanoformulations to counter molecular consequences of hypoxia, and theranostics combining hypoxia detection systems with drug delivery systems. This book disseminates the current implications of smart nanomaterials in disease management that can be exploited by scholars, researchers, and pharma industries to develop, manufacture, and commercialize hypoxia targeted diagnostics and therapeutics.

Smart Nanomaterials in Biomedical Applications

Smart Nanomaterials in Biomedical Applications PDF Author: Jin-Chul Kim
Publisher: Springer Nature
ISBN: 3030842622
Category : Medical
Languages : en
Pages : 603

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Book Description
With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Functionalized Smart Nanomaterials for Point-of-Care Testing

Functionalized Smart Nanomaterials for Point-of-Care Testing PDF Author: Amit Kumar Mandal
Publisher: Springer Nature
ISBN: 9819957877
Category : Technology & Engineering
Languages : en
Pages : 260

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Book Description
This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing ‘smart’ nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of ‘smart’ nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices.

Carbon-Based Nanomaterials

Carbon-Based Nanomaterials PDF Author: Archana (Joshi) Bachheti
Publisher: Springer Nature
ISBN: 9819702402
Category :
Languages : en
Pages : 397

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Book Description


Nanotechnology in Drug Discovery

Nanotechnology in Drug Discovery PDF Author: Laksiri Weerasinghe
Publisher: Bentham Science Publishers
ISBN: 9815238825
Category : Medical
Languages : en
Pages : 222

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Book Description
This book provides a compressive overview of nanotechnology in modern drug discovery for students and researchers. The book starts with the fundamentals of nanotechnology followed by nanomaterials in pharmaceutical drug design, drug delivery applications, regulatory aspects, formulation and nanoparticle biotransformation. It provides a step by step guide through the drug development process while conveying information about the benefits of nanomaterials for therapy. The book concludes with perspective on the future of nanotechnology-based drug discovery, summarizing current knowledge on nanotherapeutics and translational medicine. Key Features - Explains the fundamentals of nanotechnology in drug discovery - Includes up-to-date information on modern nanopharmaceutical manufacturing, nanomaterials, and nanoparticle-based drug therapy - Practice questions for learners and a list of references for advanced readers for each chapter.

Metal and Metal-Oxide Based Nanomaterials

Metal and Metal-Oxide Based Nanomaterials PDF Author: Rakesh Kumar Bachheti
Publisher: Springer Nature
ISBN: 9819976731
Category : Technology & Engineering
Languages : en
Pages : 350

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Book Description
The book in hand, namely “Metal and Metal-Oxide Based Nanomaterials (Synthesis, Agricultural, Biomedical and Environmental Interventions”, focuses on the synthesis methods, characterization techniques, and diverse interventions utilizing these nanomaterials in the fields of agriculture, biomedicine, and environmental remediation. The specific applications discussed include food packaging, post-harvest disease management, crop production, drug delivery systems, other biomedical applications, photocatalytic degradation of environmental pollutants, and wastewater treatment. Additionally, it also addresses the potential risks associated with zinc nanoparticles in aquatic ecosystems and emphasizes the importance of further research and regulation in this field. Overall, the book provides valuable insights and serves as a comprehensive resource for researchers and scientists across various interdisciplinary subjects. It serves as a valuable resource for scientists, researchers, and students in nanotechnology, nanomedicine, environmental science, plant science, agriculture, chemistry, biotechnology, pharmacognosy, pharmaceuticals, industrial chemistry, and other interdisciplinary subjects. Moreover, this also inspires further research, innovation, and the development of sustainable solutions for a better future.

Hormonal Imbalance-Associated Oxidative Stress and Protective Benefits of Nutritional Antioxidants

Hormonal Imbalance-Associated Oxidative Stress and Protective Benefits of Nutritional Antioxidants PDF Author: Sutapa Mukherjee
Publisher: Frontiers Media SA
ISBN: 2832544940
Category : Medical
Languages : en
Pages : 203

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Book Description


Smart Nanomaterials for Bioencapsulation

Smart Nanomaterials for Bioencapsulation PDF Author: Guillermo R. Castro
Publisher: Elsevier
ISBN: 0323913970
Category : Technology & Engineering
Languages : en
Pages : 298

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Book Description
Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more. Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, and more help determine the in vivo performance of the bioencapsulated food and drug derivatives. Outlines the major design principles surrounding the encapsulation of drugs, drug release, food and nutraceuticals at the nanoscale Discusses the pros and cons of different bioencapsulation methods for different application areas Outlines the major challenges of applying nanobioencapsulation at an industrial scale

Target-Triggered Nanoparticles for Tumor Diagnosis and Therapy

Target-Triggered Nanoparticles for Tumor Diagnosis and Therapy PDF Author: Yi Hou
Publisher: Frontiers Media SA
ISBN: 288966855X
Category : Science
Languages : en
Pages : 90

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Book Description


Smart Micro- and Nanomaterials for Pharmaceutical Applications

Smart Micro- and Nanomaterials for Pharmaceutical Applications PDF Author: Ajit Behera
Publisher: CRC Press
ISBN: 1040033628
Category : Technology & Engineering
Languages : en
Pages : 348

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Book Description
Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control. This approach has several advantages, including maximizing the therapeutic effects of a drug while minimizing side effects. This book presents various stimuli-responsive micro- and nanomaterials for pharmaceutical industries. This volume: Covers the global market perspective of micro- and nano-smart materials in pharmaceutical industries. Details various processing routes. Discusses mechanisms for target release. Addresses applications in oral drug delivery, anticancer agents, anti-tumor drug delivery, and drugs for management of infection. This reference work is written to support researchers in the fields of materials engineering and biotechnology with the goal of improving the diagnosis and treatment of disease and patient quality of life.