Silicone Adhesives in Medical Applications PDF Download
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Author: Gerald K. Schalau
Publisher:
ISBN:
Category : Technology
Languages : en
Pages :
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Book Description
This chapter will review silicone based adhesive technologies, applications and characterization, emphasizing those self-adhesive materials often used in skin contact applications including transdermal drug delivery and wound care device attachment. The silicone pressure sensitive adhesives used in transdermal applications today are thermoplastic and based on silicone polymer and silicate resin chemistries. Previous research has suggested that some drugs readily diffuse through silicone adhesives, prompting their use in transdermal patches. A recently developed silicone acrylate hybrid adhesive technology combines polyacrylate and silicone molecular structures to form a stable, semi-interpenetrated network. This technology provides ease in formulating transdermal drug delivery systems through improved physical stability over simple blends of acrylate and silicone adhesives. The ability of some silicone adhesives to affix bandages without disrupting the wound bed upon removal has led to the wide acceptance of a third type of silicone adhesive technology that unlike the aforementioned thermoplastic materials is thermoset. This adhesive form is based on a platinum catalyzed, cross-linking reaction between vinyl functional and silicon-hydride functional silicone polymers. The various silicone adhesive types have been characterized via classical measurements of physical performances. Rheological techniques elucidated herein provide further understanding of the structure-property relationships previously unavailable using classical characterization approaches.
Author: Gerald K. Schalau
Publisher:
ISBN:
Category : Technology
Languages : en
Pages :
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Book Description
This chapter will review silicone based adhesive technologies, applications and characterization, emphasizing those self-adhesive materials often used in skin contact applications including transdermal drug delivery and wound care device attachment. The silicone pressure sensitive adhesives used in transdermal applications today are thermoplastic and based on silicone polymer and silicate resin chemistries. Previous research has suggested that some drugs readily diffuse through silicone adhesives, prompting their use in transdermal patches. A recently developed silicone acrylate hybrid adhesive technology combines polyacrylate and silicone molecular structures to form a stable, semi-interpenetrated network. This technology provides ease in formulating transdermal drug delivery systems through improved physical stability over simple blends of acrylate and silicone adhesives. The ability of some silicone adhesives to affix bandages without disrupting the wound bed upon removal has led to the wide acceptance of a third type of silicone adhesive technology that unlike the aforementioned thermoplastic materials is thermoset. This adhesive form is based on a platinum catalyzed, cross-linking reaction between vinyl functional and silicon-hydride functional silicone polymers. The various silicone adhesive types have been characterized via classical measurements of physical performances. Rheological techniques elucidated herein provide further understanding of the structure-property relationships previously unavailable using classical characterization approaches.
Author: André Colas
Publisher: Elsevier Inc. Chapters
ISBN: 0128076690
Category : Technology & Engineering
Languages : en
Pages : 35
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Book Description
Silicone materials have been widely used in medicine for over 60 years. Available in a variety of material types, they have unique chemical and physical properties that manifest in excellent biocompatibility and biodurability for many applications. Silicone elastomers have remarkably low glass-transition temperatures and maintain their flexibility over a wide temperature range, enabling them to withstand conditions from cold storage to steam autoclaving. They have high permeability to gases and many drugs, advantageous respectively in wound care or in transdermal drug delivery. They have low surface tension and remarkable chemical stability, enabling biocompatibility and biodurability in many long-term implant applications.
Author: Halil Ozer
Publisher: BoD – Books on Demand
ISBN: 9535138391
Category : Technology & Engineering
Languages : en
Pages : 146
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Book Description
This book brings together scientists and provides the reader with a comprehensive overview of some recent developments in the field of adhesive bonding with the contributions of internationally recognized authors. This book is divided into three sections: "Structural Adhesive Bonding," "Wood Adhesive Bonding," and "Adhesive Bonding in Medical Applications." Each section presents an important review and some applications of the adhesive bonding in various different disciplines. I hope that the book published in open access will help researchers to benefit from it.
Author: Sina Ebnesajjad
Publisher: Elsevier Inc. Chapters
ISBN: 0128076682
Category : Technology & Engineering
Languages : en
Pages : 61
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Book Description
This chapter focuses on adhesives used in direct physiological contact in dental and medical procedures. Activity in both areas has been quite extensive outside the United States for decades. In contrast, adhesive use in medical devices, patches, and plasters has been ongoing in the United States for a long time. In the case of medical devices, adhesion is concerned with the joining of materials such as plastics, elastomers, textiles, metals, and ceramics, which are examined in other chapters of the present volume and are covered in various references [1–6], The coverage of this chapter is devoted to applications where to adhesives are in direct contact with tissues and other live organs.
Author: Kayvon Modjarrad
Publisher: Elsevier
ISBN: 0323221696
Category : Medical
Languages : en
Pages : 365
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Book Description
While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they're creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. - Gathers discussions of a large number of applications of polymers in medicine in one place - Provides an insight into both the legal and clinical implications of device design - Relevant to industry, academic and medical professionals - Presents the latest developments in the field, including medical devices on a nano-scale
Author: Hyun Joong Yoon
Publisher:
ISBN:
Category :
Languages : en
Pages : 160
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Book Description
Author: Walter Noll
Publisher: Elsevier
ISBN: 0323141404
Category : Technology & Engineering
Languages : en
Pages : 716
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Book Description
Chemistry and Technology of Silicones retains the nature of a monograph despite its expanded scope, giving the reader in condensed form not only a wide-ranging but also a thorough review of this rapidly growing field. In contrast to some other monographs on organosilicon compounds that have appeared in the interim, the silicones occupy in this edition the central position, and the technological part of the work is entirely devoted to them. This book comprises 12 chapters, and begins with a general discussion of the chemistry and molecular structure of the silicones. The following chapters then discuss preparation of silanes with nonfunctional organic substituents; monomeric organosilicon compounds RnSiX4-n; and organosilanes with organofunctional groups. Other chapters cover preparation of polyorganosiloxanes; the polymeric organosiloxanes; other organosilicon polymers; production of technical silicone products from polyorganosiloxanes; properties of technical products; applications of technical silicone products in various branches of industry; esters of silicic acid; and analytical methods. This book will be of interest to practitioners in the fields of molecular chemistry.
Author: P. Vandereecken
Publisher:
ISBN:
Category : Adhesion
Languages : en
Pages : 10
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Book Description
Beyond their application as sealants, silicone formulations are used as adhesives in insulated glass and structural glazing applications. The adhesion durability of such assemblies is a function of both the adhesion at the glass-interface surfaces and the internal cohesion of the adhesive. Failure in the bulk of the adhesive will occur if external stresses exceed the ultimate strength of the adhesive or when the movement capability of the adhesive is lower than required by the application. The most often observed reasons for failure are, however, substrate-adhesive interface ruptures. If similar silicone adhesives are used in different building projects, the substrates can vary widely, leading to many different interfaces. Interface adhesion can be improved by modifying the substrate surface, modifying the adhesive formulation, or using a primer. In this work, improved adhesion durability on different substrates will be shown with an improved version of a two-part silicone adhesive used for insulated glass and structural glazing applications, which was introduced in Europe in 2010. Results without primer and with the use of either a wet primer or a dry SiOx (Pyrosil®) flame treatment will be shown. Adhesion durability after water immersion, UV irradiation, and high humidity will be reported for new low E insulated glass coatings, powder coated aluminum, stainless steel, and some other standard building substrates.
Author: Istvan Benedek
Publisher: CRC Press
ISBN: 9780203021163
Category : Science
Languages : en
Pages : 772
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Book Description
Pressure-Sensitive Adhesives and Applications, Second Edition explains how pressure-sensitive adhesives (PSAs) work, why they are used, and the technology used to manufacture them. This second edition features the latest developments in the field. Dr. Benedek discusses the factors that affect the rheology and special flow characteristics res
Author: Anna Rudawska
Publisher: BoD – Books on Demand
ISBN: 9535127837
Category : Science
Languages : en
Pages : 400
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Book Description
This book presents some information regarding adhesives which have applications in industry, medicine and dentistry. The book is divided into two parts: "Adhesives Applications in Medicine and Dentistry" and "Properties of Adhesive." The aim of such a presentation is to present the usage in very different aspects of application of the adhesives and present specific properties of adhesives. Adhesives' advantageous properties and relatively uncomplicated processing methods contribute to their increasing application and their growing popularity in the industry, medicine and other branches. Some adhesives represent properties superior to those of most adhesive materials, due to their excellent adhesion and chemical resistance. A wide variety of adhesives' considerable flexibility in modification of properties of adhesives allows adjusting the composition to particular applications.
