Sex-Specific Reporting of Scientific Research

Sex-Specific Reporting of Scientific Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309225248
Category : Medical
Languages : en
Pages : 72

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Book Description
The number of women participating in clinical trials has increased during the last two decades, but women are still underrepresented in clinical trials in general. Some of the overall increase can be attributed to the greater number of women-only trials (of therapies for diseases that affect only women). Even when women are included in clinical trials, the results are often not analyzed separately by sex. On August 30, 2011, the Institute of Medicine (IOM) Board on Population Health and Public Health Practice hosted the workshop Sex-Specific Reporting of Scientific Research. The workshop explored the need for sex-specific reporting of scientific results; potential barriers and unintended consequences of sex-specific reporting of scientific results; experiences of journals that have implemented sex-specific requirements, including the challenges and benefits of such editorial policies; and steps to facilitate the reporting of sex-specific results. Presenters and participants included current and former editors of scientific journals, researchers, and scientists and policymakers from government, industry, and nonprofit organizations. Presentations and discussions highlighted the importance to both women and men of having sex-specific data, the problems with sample size and financial constraints for conducting the research, the appropriateness of sex-specific analyses, and the limitations of journal policies to change experimental designs. Sex-Specific Reporting of Scientific Research summarizes the presentations and discussions by the expert panelists during the IOM workshop. The workshop's first session focused on why sex-specific reporting is important. Panelists highlighted historical and current events that have hindered or helped to advance the study of women. In the next session, panelists in academe discussed the challenges of collecting, analyzing, and reporting sex-specific data from the researcher's perspective. That was followed by two panels of leading journal editors who shared their experiences in developing and implementing editorial policies and the implications of sex-specific reporting policies for journals.

Sex-Specific Reporting of Scientific Research

Sex-Specific Reporting of Scientific Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309225248
Category : Medical
Languages : en
Pages : 72

Get Book

Book Description
The number of women participating in clinical trials has increased during the last two decades, but women are still underrepresented in clinical trials in general. Some of the overall increase can be attributed to the greater number of women-only trials (of therapies for diseases that affect only women). Even when women are included in clinical trials, the results are often not analyzed separately by sex. On August 30, 2011, the Institute of Medicine (IOM) Board on Population Health and Public Health Practice hosted the workshop Sex-Specific Reporting of Scientific Research. The workshop explored the need for sex-specific reporting of scientific results; potential barriers and unintended consequences of sex-specific reporting of scientific results; experiences of journals that have implemented sex-specific requirements, including the challenges and benefits of such editorial policies; and steps to facilitate the reporting of sex-specific results. Presenters and participants included current and former editors of scientific journals, researchers, and scientists and policymakers from government, industry, and nonprofit organizations. Presentations and discussions highlighted the importance to both women and men of having sex-specific data, the problems with sample size and financial constraints for conducting the research, the appropriateness of sex-specific analyses, and the limitations of journal policies to change experimental designs. Sex-Specific Reporting of Scientific Research summarizes the presentations and discussions by the expert panelists during the IOM workshop. The workshop's first session focused on why sex-specific reporting is important. Panelists highlighted historical and current events that have hindered or helped to advance the study of women. In the next session, panelists in academe discussed the challenges of collecting, analyzing, and reporting sex-specific data from the researcher's perspective. That was followed by two panels of leading journal editors who shared their experiences in developing and implementing editorial policies and the implications of sex-specific reporting policies for journals.

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309132975
Category : Medical
Languages : en
Pages : 287

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Book Description
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Sex-Specific Reporting of Scientific Research

Sex-Specific Reporting of Scientific Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309225272
Category : Medical
Languages : en
Pages : 72

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Book Description
The number of women participating in clinical trials has increased during the last two decades, but women are still underrepresented in clinical trials in general. Some of the overall increase can be attributed to the greater number of women-only trials (of therapies for diseases that affect only women). Even when women are included in clinical trials, the results are often not analyzed separately by sex. On August 30, 2011, the Institute of Medicine (IOM) Board on Population Health and Public Health Practice hosted the workshop Sex-Specific Reporting of Scientific Research. The workshop explored the need for sex-specific reporting of scientific results; potential barriers and unintended consequences of sex-specific reporting of scientific results; experiences of journals that have implemented sex-specific requirements, including the challenges and benefits of such editorial policies; and steps to facilitate the reporting of sex-specific results. Presenters and participants included current and former editors of scientific journals, researchers, and scientists and policymakers from government, industry, and nonprofit organizations. Presentations and discussions highlighted the importance to both women and men of having sex-specific data, the problems with sample size and financial constraints for conducting the research, the appropriateness of sex-specific analyses, and the limitations of journal policies to change experimental designs. Sex-Specific Reporting of Scientific Research summarizes the presentations and discussions by the expert panelists during the IOM workshop. The workshop's first session focused on why sex-specific reporting is important. Panelists highlighted historical and current events that have hindered or helped to advance the study of women. In the next session, panelists in academe discussed the challenges of collecting, analyzing, and reporting sex-specific data from the researcher's perspective. That was followed by two panels of leading journal editors who shared their experiences in developing and implementing editorial policies and the implications of sex-specific reporting policies for journals.

General Considerations for the Clinical Evaluation of Drugs

General Considerations for the Clinical Evaluation of Drugs PDF Author: United States. Food and Drug Administration. Bureau of Drugs
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 20

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Book Description


Women's Health Research

Women's Health Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309163374
Category : Medical
Languages : en
Pages : 439

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Book Description
Even though slightly over half of the U.S. population is female, medical research historically has neglected the health needs of women. However, over the past two decades, there have been major changes in government support of women's health research-in policies, regulations, and the organization of research efforts. To assess the impact of these changes, Congress directed the Department of Health and Human Services (HHS) to ask the IOM to examine what has been learned from that research and how well it has been put into practice as well as communicated to both providers and women. Women's Health Research finds that women's health research has contributed to significant progress over the past 20 years in lessening the burden of disease and reducing deaths from some conditions, while other conditions have seen only moderate change or even little or no change. Gaps remain, both in research areas and in the application of results to benefit women in general and across multiple population groups. Given the many and significant roles women play in our society, maintaining support for women's health research and enhancing its impact are not only in the interest of women, they are in the interest of us all.

Research on Women's Health

Research on Women's Health PDF Author:
Publisher:
ISBN:
Category : Women
Languages : en
Pages : 84

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Book Description


Women and Health Research

Women and Health Research PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030904992X
Category : Medical
Languages : en
Pages : 286

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Book Description
In the nineteenth century some scientists argued that women should not be educated because thinking would use energy needed by the uterus for reproduction. The proof? Educated women had a lower birth rate. Today's researchers can only shake their heads at such reasoning. Yet professional journals and the popular press are increasingly criticizing medical research for ignoring women's health issues. Women and Health Research examines the facts behind the public's perceptions about women participating as subjects in medical research. With the goal of increasing researchers' awareness of this important topic, the book explores issues related to maintaining justice (in its ethical sense) in clinical studies. Leading experts present general principles for the ethical conduct of research on womenâ€"principles that are especially important in the light of recent changes in federal policy on the inclusion of women in clinical research. Women and Health Research documents the historical shift from a paternalistic approach by researchers toward women and a disproportionate reliance on certain groups for research to one that emphasizes proper access for women as subjects in clinical studies in order to ensure that women receive the benefits of research. The book addresses present-day challenges to equity in four areas: Scientificâ€"Do practical aspects of scientific research work at cross-purposes to gender equity? Focusing on drug trials, the authors identify rationales for excluding people from research based on demographics. Social and Ethicalâ€"The authors offer compelling discussions on subjectivity in science, the evidence for male bias, and issues related to race and ethnicity, as well as the recruitment, retention, and protection of research participants. Legalâ€"Women and Health Research reviews federal research policies that affect the inclusion of women and evaluates the basis for researchers' fears about liability, citing court cases. Riskâ€"The authors focus on risks to reproduction and offspring in clinical drug trials, exploring how risks can be identified for study participants, who should make the assessment of risk and benefit for participation in a clinical study, and how legal implications could be addressed. This landmark study will be of immediate use to the research community, policymakers, women's health advocates, attorneys, and individuals.

Evidence-Based Women's Oral Health, An Issue of Dental Clinics

Evidence-Based Women's Oral Health, An Issue of Dental Clinics PDF Author: Leslie R. Halpern
Publisher: Elsevier Health Sciences
ISBN: 1455771686
Category : Medical
Languages : en
Pages : 281

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Book Description
This issue of Dental Clinics features expert clinical reviews on Evidence-Based Women's Oral Health which includes current information on topics such as strategic planning for prioritizing oral health gender disparities, oral health gender disparities and systemic health, oral health gender disparities and reproductive health, oral cancer in women, risk assessment and management, tooth loss, dietary behaviors and oral health in women, enamel erosion, violence and abuse, temporomandibular joint disorder, gender differences and the aging and diseased jaw, patient-provider interactions, and pathways to assure evidence-based women’s oral health.

Gender Differences in the Pathogenesis and Management of Heart Disease

Gender Differences in the Pathogenesis and Management of Heart Disease PDF Author: Jawahar L. Mehta
Publisher: Springer
ISBN: 3319711350
Category : Medical
Languages : en
Pages : 361

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Book Description
This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

The Oxford Handbook of Research Ethics

The Oxford Handbook of Research Ethics PDF Author: Ana S. Iltis
Publisher: Oxford University Press
ISBN: 0190947756
Category : Business & Economics
Languages : en
Pages : 937

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Book Description
The development of new pharmaceutical products and behavioral interventions aimed at improving people's health, as well as research that assesses the efficacy and cost-effectiveness of public policies, such as policies designed to improve children's education or reduce poverty, depends on research conducted with human participants. It is imperative that research with human subjects is conducted in accordance with sound ethical principles and regulatory requirements. Featuring 45 original essays by leading research ethicists, The Oxford Handbook of Research Ethics offers a critical overview of the ethics of human subjects research within multiple disciplines and fields, including biomedicine, public health, psychiatry, sociology, political science, and public policy.