Serotonin and Sleep: Molecular, Functional and Clinical Aspects

Serotonin and Sleep: Molecular, Functional and Clinical Aspects PDF Author: Jaime M. Monti
Publisher: Springer Science & Business Media
ISBN: 3764385618
Category : Medical
Languages : en
Pages : 627

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Book Description
This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.

Serotonin and Sleep: Molecular, Functional and Clinical Aspects

Serotonin and Sleep: Molecular, Functional and Clinical Aspects PDF Author: Jaime M. Monti
Publisher: Springer Science & Business Media
ISBN: 3764385618
Category : Medical
Languages : en
Pages : 627

Get Book Here

Book Description
This book focuses on the neuropsychopharmacology of serotonin and its role in sleep and wakefulness, presenting neurochemical, electrophysiological, and neuropharmacological approaches to understand the mechanisms of serotonin and related substances. Covering core and contemporary topics in the area, this volume is valuable for all researchers interested in interdisciplinary studies concerning drugs affecting the central nervous system.

Sleep Disorders and Sleep Deprivation

Sleep Disorders and Sleep Deprivation PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309101115
Category : Medical
Languages : en
Pages : 425

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Book Description
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

The Role of Protein and Amino Acids in Sustaining and Enhancing Performance

The Role of Protein and Amino Acids in Sustaining and Enhancing Performance PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309172810
Category : Technology & Engineering
Languages : en
Pages : 448

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Book Description
It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.

Inherited Metabolic Disease in Adults

Inherited Metabolic Disease in Adults PDF Author: Carla E. M. Hollak
Publisher: Oxford University Press
ISBN: 0199972133
Category : Medical
Languages : en
Pages : 657

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Book Description
As clinical management of inherited metabolic diseases (IMDs) has improved, more patients affected by these conditions are surviving into adulthood. This trend, coupled with the widespread recognition that IMDs can present differently and for the first time during adulthood, makes the need for a working knowledge of these diseases more important than ever. Inherited Metabolic Disease in Adults offers an authoritative clinical guide to the adult manifestations of these challenging and myriad conditions. These include both the classic pediatric-onset conditions and a number of new diseases that can manifest at any age. It is the first book to give a clear and concise overview of how this group of conditions affects adult patients, a that topic will become a growing imperative for physicians across primary and specialized care.

Sleep and Wakefulness

Sleep and Wakefulness PDF Author: Nathaniel Kleitman
Publisher: University of Chicago Press
ISBN: 9780226440736
Category : Medical
Languages : en
Pages : 566

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Book Description
For half a century, Sleep and Wakefulness has been a valuable reference work. It discusses phases of the sleep cycle, experimental work on sleep and wakefulness, sleep disorders and their treatment, and such sleep-like states as hypnosis and hibernation.

Sleep and Mental Illness

Sleep and Mental Illness PDF Author: S. R. Pandi-Perumal
Publisher: Cambridge University Press
ISBN: 1139483706
Category : Medical
Languages : en
Pages : 451

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Book Description
The diagnosis of mental illness is frequently accompanied by sleep problems; conversely, people experiencing sleep problems may subsequently develop mental illness. Sleep and Mental Illness looks at this close correlation and considers the implications of research findings that have emerged in the last few years. Additionally, it surveys the essential concepts and practical tools required to deal with sleep and co-morbid psychiatric problems. The volume is divided into three main sections: basic science, neuroendocrinology, and clinical science. Included are over 30 chapters on topics such as neuropharmacology, insomnia, depression, dementia, autism, and schizophrenia. Relevant questionnaires for the assessment of sleep disorders, including quality-of-life measurement tools, are provided. There is also a summary table of drugs for treating sleep disorders. This interdisciplinary text will be of interest to clinicians working in psychiatry, behavioral sleep medicine, neurology, pulmonary and critical care medicine.

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin PDF Author:
Publisher: Academic Press
ISBN: 0444641262
Category : Psychology
Languages : en
Pages : 1044

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Book Description
Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment. Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood. - Features two new sections on serotonin systems interactions and serotonin in neurological disorders - Focuses on ionotropic and metabotropic 5-HT receptor involvement in behavior - Maps receptors and receptor signaling pathways to neurochemical and behavioral outcomes - Covers the interactions between serotonin, melatonin and kynurenine pathways

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin PDF Author: Christian P. Muller
Publisher: Academic Press
ISBN: 0080878172
Category : Science
Languages : en
Pages : 849

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Book Description
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. - The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system - Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others - The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community - Of great value not only for researchers and experts, but also for students and clinicians as a background reference

Neurochemistry of Sleep and Wakefulness

Neurochemistry of Sleep and Wakefulness PDF Author: Jaime Monti
Publisher: Cambridge University Press
ISBN: 9780521864411
Category : Medical
Languages : en
Pages : 506

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Book Description
Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.

Rapid Eye Movement Sleep

Rapid Eye Movement Sleep PDF Author: MallIck/Inoue
Publisher: CRC Press
ISBN: 9780824703226
Category : Science
Languages : en
Pages : 450

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Book Description
This reference also includes nine color plates. Written by leading international scientists in the field, this comprehensive and up-to-date reference provides detailed coverage of various aspects of rapid eye movement sleep (REMS)-including phylogeny and evolution, ontogeny, neurophysiological and neurochemical phenomena, molecular processes, behavioral and physiological changes due to deprivation, and hypotheses on the neurodynamics of REMS. Examining the relationship between the neocortex in mammals and birds in the evolution of REM sleep, Rapid Eye Movement Sleep considers the roles of REMS in the maturation of the brain reveals a new theory that challenges the assumption that REM is solely initiated by bulbar mechanisms in intact animals explores experimental studies of REMS atonia and the mechanisms underlying tonic and phasic muscle atonia describes the cellular and molecular mechanisms and function of pontine ponto-geniculo-occipatal waves during REMS details the role of nitric oxide in the regulation of REMS summarizes new evidence on which neurotransmitters are responsible for the REMS generating mechanism presents an overview of several endogenous sleep substances that may positively or negatively regulate REMS and more. Rapid Eye Movement Sleep serves as essential reading for all researchers and clinicians in the study of sleep science, particularly physiologists and biologists; neurologists, neuropsychiatrists, psychiatrists, and psychologists; anesethiologists; and pharmacologists.